Search Results - "Lopes, A Ross"

Role of the coinhibitory receptor cytotoxic T lymphocyte antigen‐4 on apoptosis‐Prone CD8 T cells in persistent hepatitis B virus infection by Schurich, Anna, Khanna, Pooja, Lopes, A. Ross, Han, Ki Jun, Peppa, Dimitra, Micco, Lorenzo, Nebbia, Gaia, Kennedy, Patrick T.F., Geretti, Anna‐Maria, Dusheiko, Geoffrey, Maini, Mala K.

“…An excess of coinhibitory signals has been proposed to drive the T‐cell exhaustion characteristic of persistent viral infections. In this study we examined the…”
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IL-10-producing regulatory B cells in the pathogenesis of chronic hepatitis B virus infection by Das, Abhishek, Ellis, Gidon, Pallant, Celeste, Lopes, A Ross, Khanna, Pooja, Peppa, Dimitra, Chen, Antony, Blair, Paul, Dusheiko, Geoffrey, Gill, Upkar, Kennedy, Patrick T, Brunetto, Maurizia, Lampertico, Pietro, Mauri, Claudia, Maini, Mala K

“…A regulatory subset of B cells has been found to modulate immune responses in autoimmunity, infection, and cancer, but it has not been investigated in the…”
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Cytokines induced during chronic hepatitis B virus infection promote a pathway for NK cell-mediated liver damage by Dunn, Claire, Brunetto, Maurizia, Reynolds, Gary, Christophides, Theodoros, Kennedy, Patrick T, Lampertico, Pietro, Das, Abhishek, Lopes, A Ross, Borrow, Persephone, Williams, Kevin, Humphreys, Elizabeth, Afford, Simon, Adams, David H, Bertoletti, Antonio, Maini, Mala K

“…Hepatitis B virus (HBV) causes chronic infection in more than 350 million people worldwide. It replicates in hepatocytes but is non-cytopathic; liver damage is…”
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Effect of HIV Infection and Antiretroviral Therapy on Hepatitis B Virus (HBV)–Specific T Cell Responses in Patients Who Have Resolved HBV Infection by Lascar, R. Monica, Lopes, A. Ross, Gilson, Richard J., Dunn, Claire, Johnstone, Ruth, Copas, Andrew, Reignat, Stephanie, Webster, George, Bertoletti, Antonio, Maini, Mala K.

“…Coinfection with hepatitis B virus (HBV) is a common occurrence in human immunodeficiency virus (HIV)–positive patients and an increasing cause of morbidity…”
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Bim-mediated deletion of antigen-specific CD8 T cells in patients unable to control HBV infection by Lopes, A Ross, Kellam, Paul, Das, Abhishek, Dunn, Claire, Kwan, Antonia, Turner, Joanna, Peppa, Dimitra, Gilson, Richard J, Gehring, Adam, Bertoletti, Antonio, Maini, Mala K

“…HBV-specific CD8(+) T cells are critical for a successful immune response to HBV infection. They are markedly diminished in number in patients who fail to…”
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Functional skewing of the global CD8 T cell population in chronic hepatitis B virus infection by Das, Abhishek, Hoare, Matthew, Davies, Nathan, Lopes, A Ross, Dunn, Claire, Kennedy, Patrick T F, Alexander, Graeme, Finney, Helene, Lawson, Alistair, Plunkett, Fiona J, Bertoletti, Antonio, Akbar, Arne N, Maini, Mala K

“…The inflamed liver in chronic hepatitis B virus (HBV) infection (CHB) is characterized by a large influx of non-virus-specific CD8 T cells. Little is known…”
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Reconstitution of Hepatitis B Virus (HBV)–Specific T Cell Responses with Treatment of Human Immunodeficiency Virus/HBV Coinfection by Lascar, R. Monica, Gilson, Richard J., Lopes, A. Ross, Bertoletti, Antonio, Maini, Mala K.

“…Liver-related mortality is an increasing problem in human immunodeficiency virus (HIV)/hepatitis B virus (HBV)–coinfected patients receiving highly active…”
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Greater CD8+ TCR Heterogeneity and Functional Flexibility in HIV-2 Compared to HIV-1 Infection by Lopes, A. Ross, Jaye, Assan, Dorrell, Lucy, Sabally, Sehu, Alabi, Abraham, Jones, Nicola A, Flower, Darren R, De Groot, Anne, Newton, Phillipa, Lascar, R. Monica, Williams, Ian, Whittle, Hilton, Bertoletti, Antonio, Borrow, Persephone, Maini, Mala K

“…Virus-specific CD8(+) T cells are known to play an important role in the control of HIV infection. In this study we investigated whether there may be…”
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HIV-1 Epitope-Specific CD8+ T Cell Responses Strongly Associated with Delayed Disease Progression Cross-Recognize Epitope Variants Efficiently by Turnbull, Emma L, Lopes, A. Ross, Jones, Nicola A, Cornforth, David, Newton, Phillipa, Aldam, Diana, Pellegrino, Pierre, Turner, Jo, Williams, Ian, Wilson, Craig M, Goepfert, Paul A, Maini, Mala K, Borrow, Persephone

“…The ability of HIV-1-specific CD8(+) T cell responses to recognize epitope variants resulting from viral sequence variation in vivo may affect the ease with…”
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IL-10 producing regulatory B cells in the pathogenesis of chronic HBV infection12 by Das, Abhishek, Ellis, Gidon, Pallant, Celeste, Lopes, A. Ross, Khanna, Pooja, Peppa, Dimitra, Chen, Antony, Blair, Paul, Dusheiko, Geoffrey, Gill, Upkar, Kennedy, Patrick T, Brunetto, Maurizia, Lampertico, Pietro, Mauri, Claudia, Maini, Mala K.

“…A regulatory subset of B cells has been found to modulate immune responses in autoimmunity, infection and cancer but has not been investigated in the setting…”
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Randomized trial of lamivudine versus hepatitis B immunoglobulin for long-term prophylaxis of hepatitis B recurrence after liver transplantation by Naoumov, Nikolai V, Lopes, A.Ross, Burra, Patrizia, Caccamo, Lucio, Iemmolo, Rosa M, de Man, Robert A, Bassendine, Margaret, O'Grady, John G, Portmann, Bernard C, Anschuetz, Gaya, Barrett, Catherine A, Williams, Roger, Atkins, Mark

“…Background/Aims : The long-term prophylaxis of hepatitis B after liver transplantation requires further optimization. In a randomized trial we investigated a…”
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Bim-mediated deletion of antigen-specific [CD8.sup.+] T cells in patients unable to control HBV infection by Lopes, A. Ross, Kellam, Paul, Das, Abhishek, Dunn, Claire, Kwan, Antonia, Turner, Joanna, Peppa, Dimitra, Gilson, Richard J, Gehring, Adam, Bertoletti, Antonio, Maini, Mala K

“…HBV-specific [CD8.sup.+] T cells are critical for a successful immune response to HBV infection. They are markedly diminished in number in patients who fail to…”
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Bim-mediated deletion of antigen-specific CD8^sup +^ T cells in patients unable to control HBV infection by Lopes, A Ross, Kellam, Paul, Das, Abhishek, Dunn, Claire, Kwan, Antonia, Turner, Joanna, Peppa, Dimitra, Gilson, Richard J, Gehring, Adam, Bertoletti, Antonio, Maini, Mala K

“…HBV-specific CD8(+) T cells are critical for a successful immune response to HBV infection. They are markedly diminished in number in patients who fail to…”
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Effect of HIV infection and antiretroviral therapy on hepatitis B virus (HBV)-spedfic T cell responses in patients who have resolved HBV infection by LASCAR, R. Monica, ROSS LOPES, A, GILSON, Richard J, DUNN, Claire, JOHNSTONE, Ruth, COPAS, Andrew, REIGNAT, Stephanie, WEBSTER, George, BERTOLETTI, Antonio, MAINI, Mala K

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CD8+ T cell attrition in chronic hepatitis B virus infection by Lopes, A Ross

“…Hepatitis B virus (HBV)-specific CD8+ T cells are critical for a successful immune response to HBV infection. These cells are markedly diminished in patients…”
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Erk-independent partial activation of AP-1 sites by the hepatitis B virus HBx protein by Henkler, F, Lopes, AR, Jones, M, Koshy, R

“…F Henkler, AR Lopes, M Jones and R Koshy Imperial College of Science, Technology and Medicine, Hammersmith Campus, Department of Infectious Diseases, London,…”
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Randomized trial of lamivudine versus hepatitis B immunoglobulin for long-term prophylaxis of hepatitis B recurrence after liver transplantation. Editorial by NAOUMOV, Nikolai V, LOPES, A. Ross, BARRETTE, Catherine A, WILLIAMS, Roger, ATKINS, Mark, SAMUEL, Didier, BURRA, Patrizia, CACCAMO, Lucio, IEMMOLO, Rosa M, DE MAN, Robert A, BASSENDINE, Margaret, O'GRADY, John G, PORTMANN, Bernard C, ANSCHUETZ, Gaya

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