Search Results - "Lopatár, Jan"

Pannexin-1-mediated ATP release from area CA3 drives mGlu5-dependent neuronal oscillations by Lopatář, Jan, Dale, Nicholas, Frenguelli, Bruno G.

“…The activation of Group I metabotropic glutamate receptors (GI mGluRs) in the hippocampus results in the appearance of persistent bursts of synchronised…”
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Synaptic Integration of Adult-Born Hippocampal Neurons Is Locally Controlled by Astrocytes by Sultan, Sébastien, Li, Liyi, Moss, Jonathan, Petrelli, Francesco, Cassé, Frédéric, Gebara, Elias, Lopatar, Jan, Pfrieger, Frank W., Bezzi, Paola, Bischofberger, Josef, Toni, Nicolas

“…Adult neurogenesis is regulated by the neurogenic niche, through mechanisms that remain poorly defined. Here, we investigated whether niche-constituting…”
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Homeostatic control of synaptic activity by endogenous adenosine is mediated by adenosine kinase by Diógenes, Maria José, Neves-Tomé, Raquel, Fucile, Sergio, Martinello, Katiuscia, Scianni, Maria, Theofilas, Panos, Lopatár, Jan, Ribeiro, Joaquim A, Maggi, Laura, Frenguelli, Bruno G, Limatola, Cristina, Boison, Detlev, Sebastião, Ana M

“…Extracellular adenosine, a key regulator of neuronal excitability, is metabolized by astrocyte-based enzyme adenosine kinase (ADK). We hypothesized that ADK…”
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G-Protein Coupled Receptor-Evoked Glutamate Exocytosis from Astrocytes: Role of Prostaglandins by Pucci, Luca, Petrelli, Francesco, Lopatar, Jan, Cali, Corrado, Bezzi, Paola

“…Astrocytes are highly secretory cells, participating in rapid brain communication by releasing glutamate. Recent evidences have suggested that this process is…”
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Homer1 Scaffold Proteins Govern Ca2+ Dynamics in Normal and Reactive Astrocytes by Buscemi, Lara, Ginet, Vanessa, Lopatar, Jan, Montana, Vedrana, Pucci, Luca, Spagnuolo, Paola, Zehnder, Tamara, Grubišić, Vladimir, Truttman, Anita, Sala, Carlo, Hirt, Lorenz, Parpura, Vladimir, Puyal, Julien, Bezzi, Paola

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The novel NTPDase inhibitor sodium polyoxotungstate (POM-1) inhibits ATP breakdown but also blocks central synaptic transmission, an action independent of NTPDase inhibition by Wall, Mark J., Wigmore, Geoffery, Lopatář, Ján, Frenguelli, Bruno G., Dale, Nicholas

“…Understanding the mechanisms and properties of purinergic signalling would be greatly assisted by the discovery of subtype selective and potent inhibitors of…”
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Minor contribution of ATP P2 receptors to electrically-evoked electrographic seizure activity in hippocampal slices: Evidence from purine biosensors and P2 receptor agonists and antagonists by Lopatář, Ján, Dale, Nicholas, Frenguelli, Bruno G.

“…While the position of adenosine as an endogenous anticonvulsant is well established, it is unclear to what extent its precursor, ATP, contributes to seizure…”
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Homer1 Scaffold Proteins Govern Ca2+ Dynamics in Normal and Reactive Astrocytes by Buscemi, Lara, Ginet, Vanessa, Lopatar, Jan, Montana, Vedrana, Pucci, Luca, Spagnuolo, Paola, Zehnder, Tamara, Grubišic, Vladimir, Truttman, Anita, Sala, Carlo, Hirt, Lorenz, Parpura, Vladimir, Puyal, Julien, Bezzi, Paola

“…In astrocytes, the intracellular calcium (Ca2+) signaling mediated by activation of metabotropic glutamate receptor 5 (mGlu5) is crucially involved in the…”
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Regulation of cortical excitability and seizure activity by purines by Lopatář, Ján

“…The purine nucleoside adenosine is considered an important endogenous anticonvulsant, which exerts its actions via adenosine receptors. Adenosine can be…”
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