Search Results - "Loosli, F"

Six3 overexpression initiates the formation of ectopic retina by Loosli, F, Winkler, S, Wittbrodt, J

“…The homeobox gene sine oculis (so) is essential for visual system formation in Drosophila. A vertebrate member of the so/Six gene family, Six3, is expressed in…”
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TRIM25 has a dual function in the p53/Mdm2 circuit by Zhang, P, Elabd, S, Hammer, S, Solozobova, V, Yan, H, Bartel, F, Inoue, S, Henrich, T, Wittbrodt, J, Loosli, F, Davidson, G, Blattner, C

“…P53 is an important tumor suppressor that, upon activation, induces growth arrest and cell death. Control of p53 is thus of prime importance for proliferating…”
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Medaka eyeless is the key factor linking retinal determination and eye growth by Loosli, F, Winkler, S, Burgtorf, C, Wurmbach, E, Ansorge, W, Henrich, T, Grabher, C, Arendt, D, Carl, M, Krone, A, Grzebisz, E, Wittbrodt, J

“…The complete absence of eyes in the medaka fish mutation eyeless is the result of defective optic vesicle evagination. We show that the eyeless mutation is…”
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The conditional medaka mutation eyeless uncouples patterning and morphogenesis of the eye by Winkler, S, Loosli, F, Henrich, T, Wakamatsu, Y, Wittbrodt, J

“…In early vertebrate eye development, the retinal anlage is specified in the anterior neuroectoderm. During neurulation, the optic vesicles evaginate from the…”
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Medaka spalt acts as a target gene of hedgehog signaling by Koster, R, Stick, R, Loosli, F, Wittbrodt, J

“…In vertebrates, pattern formation in the eye, central nervous system, somites, and limb depends on hedgehog activity, but a general target gene controlled by…”
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Isolation of a Pax-6 Homolog from the Ribbonworm Lineus sanguineus by Loosli, F, Kmita-Cunisse, M, Gehring, W J

“…The Pax-6 genes of vertebrates and Drosophila encode transcription factors with highly conserved paired-and homeodomains. They are expressed in the nervous…”
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Viscoelasticity of model surfactant solutions determined by rotational magnetic spectroscopy by Loosli, F., Najm, M., Berret, Jean-Francois

“…Being able to reduce the size of a rheometer down to the micron scale is a unique opportunity to explore the mechanical response of expensive and/or confined…”
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Viscoelasticity of model surfactant solutions determined by magnetic rotation spectroscopy by Loosli, F., Najm, M., Berret, J.-F.

“…[Display omitted] •Microrheology is implemented using micron size magnetic wires.•Motion predictions are made for wires embedded in viscoelastic fluid.•The…”
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Six3 inactivation reveals its essential role for the formation and patterning of the vertebrate eye by Carl, Matthias, Loosli, Felix, Wittbrodt, Joachim

“…The establishment of retinal identity and the subsequent patterning of the optic vesicle are the key steps in early vertebrate eye development. To date little…”
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Loss of eyes in zebrafish caused by mutation of chokh/rx3 by Loosli, Felix, Staub, Wendy, Finger-Baier, Karin C, Ober, Elke A, Verkade, Heather, Wittbrodt, Joachim, Baier, Herwig

“…The vertebrate eye forms by specification of the retina anlage and subsequent morphogenesis of the optic vesicles, from which the neural retina differentiates…”
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Six3 and Six6 activity is modulated by members of the groucho family by López-Ríos, Javier, Tessmar, Kristin, Loosli, Felix, Wittbrodt, Joachim, Bovolenta, Paola

“…Six3 and Six6 are two genes required for the specification and proliferation of the eye field in vertebrate embryos, suggesting that they might be the…”
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The discovery, positioning and verification of a set of transcription-associated motifs in vertebrates by Ettwiller, Laurence, Paten, Benedict, Souren, Marcel, Loosli, Felix, Wittbrodt, Jochen, Birney, Ewan

“…We have developed several new methods to investigate transcriptional motifs in vertebrates. We developed a specific alignment tool appropriate for regions…”
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Homeobox Genes in the Ribbonworm Lineus sanguineus: Evolutionary Implications by Kmita-Cunisse, Marie, Loosli, Felix, Bierne, Jacques, Gehring, Walter J.

“…From our current understanding of the genetic basis of development and pattern formation in Drosophila and vertebrates it is commonly thought that clusters of…”
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Viscoelasticity of model surfactant solutions determined by rotational magnetic spectroscopy by Loosli, F, Najm, M, Berret, J. -F

“…Colloids and Surfaces A: Physicochemical and Engineering Aspects 510, 143 - 149 (2016) Being able to reduce the size of a rheometer down to the micron scale is…”
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Wire active microrheology to differentiate viscoelastic liquids from soft solids by Loosli, F, Najm, M, Chan, R, Oikonomou, E, Grados, A, Receveur, M, Berret, J. -F

“…ChemPhysChem 17, 4134 - 4143 (2016) Viscoelastic liquids are characterized by a finite static viscosity and a zero yield stress, whereas soft solids have an…”
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A systematic genome-wide screen for mutations affecting organogenesis in Medaka, Oryzias latipes by Furutani-Seiki, Makoto, Sasado, Takao, Morinaga, Chikako, Suwa, Hiroshi, Niwa, Katsutoshi, Yoda, Hiroki, Deguchi, Tomonori, Hirose, Yukihiro, Yasuoka, Akihito, Henrich, Thorsten, Watanabe, Tomomi, Iwanami, Norimasa, Kitagawa, Daiju, Saito, Kota, Asaka, Satoshi, Osakada, Masakazu, Kunimatsu, Sanae, Momoi, Akihiro, Elmasri, Harun, Winkler, Christoph, Ramialison, Mirana, Loosli, Felix, Quiring, Rebecca, Carl, Matthias, Grabher, Clemens, Winkler, Sylke, Del Bene, Filippo, Shinomiya, Ai, Kota, Yasuko, Yamanaka, Toshiyuki, Okamoto, Yasuko, Takahashi, Katsuhito, Todo, Takeshi, Abe, Keiko, Takahama, Yousuke, Tanaka, Minoru, Mitani, Hiroshi, Katada, Toshiaki, Nishina, Hiroshi, Nakajima, Noboru, Wittbrodt, Joachim, Kondoh, Hisato

“…A large-scale mutagenesis screen was performed in Medaka to identify genes acting in diverse developmental processes. Mutations were identified in homozygous…”
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A screen for co-factors of Six3 by Tessmar, Kristin, Loosli, Felix, Wittbrodt, Joachim

“…The vertebrate Six3 gene a homeobox gene of the Six-family, plays a crucial role in early eye and forebrain development. Here we report the isolation of…”
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Six3, a medaka homologue of the Drosophila homeobox gene sine oculis is expressed in the anterior embryonic shield and the developing eye by Loosli, Felix, Köster, Reinhard W., Carl, Matthias, Krone, Annette, Wittbrodt, Joachim

“…The conserved transcription factor Pax6 is essential for eye development in Drosophila and mammals (Hill, R.E., Favor, J., Hogan, B.L.M., Ton, C.C.T.,…”
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A genetic screen for mutations affecting embryonic development in medaka fish (Oryzias latipes) by Loosli, F, Köster, R W, Carl, M, Kühnlein, R, Henrich, T, Mücke, M, Krone, A, Wittbrodt, J

“…In a pilot screen, we assayed the efficiency of ethylnitrosourea (ENU) as a chemical mutagen to induce mutations that lead to early embryonic and larval lethal…”
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Ectopic lens induction in fish in response to the murine homeobox gene Six3 by Oliver, Guillermo, Loosli, Felix, Köster, Reinhard, Wittbrodt, Joachim, Gruss, Peter

“…Recent findings show an unexpected conservation of genes involved in vertebrate and insect eye development. The Drosophila homeobox gene sine oculis is crucial…”
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