Search Results - "Loong, David T. J"

Synthesis and Biological Evaluation of N‑((1-(4-(Sulfonyl)piperazin-1-yl)cycloalkyl)methyl)benzamide Inhibitors of Glycine Transporter‑1 by Cioffi, Christopher L, Liu, Shuang, Wolf, Mark A, Guzzo, Peter R, Sadalapure, Kashinath, Parthasarathy, Visweswaran, Loong, David T. J, Maeng, Jun-Ho, Carulli, Edmund, Fang, Xiao, Karunakaran, Kalesh, Matta, Lakshman, Choo, Sok Hui, Panduga, Shailijia, Buckle, Ronald N, Davis, Randall N, Sakwa, Samuel A, Gupta, Priya, Sargent, Bruce J, Moore, Nicholas A, Luche, Michele M, Carr, Grant J, Khmelnitsky, Yuri L, Ismail, Jiffry, Chung, Mark, Bai, Mei, Leong, Wei Yee, Sachdev, Nidhi, Swaminathan, Srividya, Mhyre, Andrew J

“…We previously disclosed the discovery of rationally designed N-((1-(4-(propylsulfonyl)­piperazin-1-yl)­cycloalkyl)­methyl)­benzamide inhibitors of glycine…”
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A chemoenzymatic total synthesis of the phytotoxic undecenolide (-)-cladospolide A by Banwell, Martin G, Loong, David T J

“…An eleven-step synthesis of the title compound (1) from biocatalytically-derived and enantiomerically pure 'building blocks' alcohol (R)-(-)-9 and ester 13 is…”
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A chemoenzymatic total synthesis of the undecenolide (-)-cladospolide B via a mid-stage ring-closing metathesis and a late-stage photo-rearrangement of the E-isomer by Austin, Kerrie A B, Banwell, Martin G, Loong, David T J, Rae, A David, Willis, Anthony C

“…A sixteen-step synthesis of the twelve-membered macrolide (-)-cladospolide B(2) from the microbially-derived cis-1,2-dihydrocatechol 5 is described. Pivotal…”
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A Pd[0]-catalyzed Ullmann cross-coupling/reductive cyclization approach to C-3 mono-alkylated oxindoles and related compounds by Banwell, Martin G., Jones, Matthew T., Loong, David T.J., Lupton, David W., Pinkerton, David M., Ray, Jayanta K., Willis, Anthony C.

“…The Pd[0]-catalyzed Ullmann cross-coupling of o-nitrohaloarenes 1a– e with the brominated heterocycles 2a– f delivers the expected products 3a– j in good to…”
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Design, synthesis, and SAR of N-((1-(4-(propylsulfonyl)piperazin-1-yl)cycloalkyl)methyl)benzamide inhibitors of glycine transporter-1 by Cioffi, Christopher L., Wolf, Mark A., Guzzo, Peter R., Sadalapure, Kashinath, Parthasarathy, Visweswaran, Dethe, Dattatraya, Maeng, Jun-Ho, Carulli, Edmund, Loong, David T.J., Fang, Xiao, Hu, Min, Gupta, Priya, Chung, Mark, Bai, Mei, Moore, Nick, Luche, Michele, Khmelnitsky, Yuri, Love, Patrick L., Watson, Megan A., Mhyre, Andrew J., Liu, Shuang

“…The design, synthesis, and structure–activity relationships (SAR) of a series of N-((1-(4-(propylsulfonyl)piperazin-1-yl)cycloalkyl)methyl)benzamide inhibitors…”
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(Z,2R,3R,4aR,7R,12aS)-2,3,7,8,12,12a-Hexahydro-2,3-dimethoxy-2,3,7-trimethyl-4aH-[1,4]dioxino[2,3-c]oxecin-5(11H)-one: a commensurate occupationally modulated structure revealing a condition for diffraction symmetry enhancement for non-parent reflections by Willis, Anthony C., Loong, David T. J., Rae, A. David, Banwell, Martin G.

“…(Z,2R,3R,4aR,7R,12aS)‐2,3,7,8,12,12a‐Hexahydro‐2,3‐dimethoxy‐2,3,7‐trimethyl‐4aH‐[1,4]dioxino[2,3‐c]oxecin‐5(11H)‐one (C16H26O6) crystallizes in the space…”
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Stereoselective Total Synthesis of the Nonenolide (+)-Microcarpalide by G. Banwell, Martin, T. J. Loong, David

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The conversion of certain microbially-derived cis- and trans-1,2-dihydrocatechols into various tetrahydro- and related-derivatives by Banwell, Martin G., Edwards, Alison J., Loong, David T. J.

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Molecular capsules and coordination polymers from a backbone-modified cyclic peptide bearing pyridyl arms by Dong, Ying, Loong, David T.J., Yuen, Alex K.L., Black, Richard J., O'Malley, Shane, Clegg, Jack K., Lindoy, Leonard F., Jolliffe, Katrina A.

“…A tris-pyridyl-substituted Lissoclinum-type cyclic peptide forms a trinuclear molecular capsule on addition of Ag(I) ions and an infinite one-dimensional…”
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( Z ,2 R ,3 R ,4a R ,7 R ,12a S )-2,3,7,8,12,12a-Hexahydro-2,3-dimethoxy-2,3,7-trimethyl-4a H -[1,4]dioxino[2,3- c ]oxecin-5(11 H )-one: a commensurate occupationally modulated structure revealing a condition for diffraction symmetry enhancement for non-parent reflections by Rae, A. David, Willis, Anthony C., Loong, David T. J., Banwell, Martin G.

“…( Z ,2 R ,3 R ,4a R ,7 R ,12 aS )-2,3,7,8,12,12 a -Hexahydro-2,3-dimethoxy-2,3,7-trimethyl-4a H -[1,4]dioxino[2,3- c ]oxecin-5(11 H )-one (C 16 H 26 O 6 )…”
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(Z,2,3R,4aR,7R,12aS)-2,3,7,8,12,12a-Hexahydro-2,3-dimethoxy-2,3,7-trimethyl-4aH-[1,4]dioxino[2,3-c]oxecin-5(11H)-one : a commen surate occupationally modulated structure revealing a condition for diffraction symmetry enhancement for non-parent reflections by RAE, A. David, WILLIS, Anthony C, LOONG, David T. J, BANWELL, Martin G

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