Search Results - "Loomis, Aaron G"

Endosomolysis by Masking of a Membrane-Active Agent (EMMA) for Cytoplasmic Release of Macromolecules by Rozema, David B, Ekena, Kirk, Lewis, David L, Loomis, Aaron G, Wolff, Jon A

“…Endosomolysis, a critical barrier to efficient delivery of macromolecules such as nucleic acids, has been breached using a novel approach:  endosomolysis by…”
Get full text

Efficient delivery of siRNA for inhibition of gene expression in postnatal mice by Lewis, David L, Hagstrom, James E, Loomis, Aaron G, Wolff, Jon A, Herweijer, Hans

“…It has recently been shown that RNA interference can be induced in cultured mammalian cells by delivery of short interfering RNAs (siRNAs). Here we describe a…”
Get full text

Efficient in vitro and in vivo expression of covalently modified plasmid DNA by Slattum, Paul S, Loomis, Aaron G, Machnik, Kira J, Watt, Mary-Anne, Duzeski, Jennifer L, Budker, Vladimir G, Wolff, Jon A, Hagstrom, James E

“…The tracking of plasmid DNA (pDNA) movement within cells requires the attachment of labels to the DNA in a manner such that: (a) the pDNA remains intact during…”
Get full text