Search Results - "Loomba, Johanna"
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Dupilumab Use Is Associated With Protection From Coronavirus Disease 2019 Mortality: A Retrospective Analysis
Published in Clinical infectious diseases (06-01-2023)“…We previously found that type 2 immunity promotes coronavirus disease 2019 (COVID-19) pathogenesis in a mouse model. To test relevance to human disease, we…”
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A Pilot Study of Focused Ultrasound Thalamotomy for Essential Tremor
Published in The New England journal of medicine (15-08-2013)“…In an uncontrolled, open-label pilot study, essential tremor improved in 15 patients treated with MRI-guided focused ultrasound thalamotomy. Adverse effects…”
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Long COVID risk and pre-COVID vaccination in an EHR-based cohort study from the RECOVER program
Published in Nature communications (22-05-2023)“…Long COVID, or complications arising from COVID-19 weeks after infection, has become a central concern for public health experts. The United States National…”
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Coding long COVID: characterizing a new disease through an ICD-10 lens
Published in BMC medicine (16-02-2023)“…Naming a newly discovered disease is a difficult process; in the context of the COVID-19 pandemic and the existence of post-acute sequelae of SARS-CoV-2…”
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IL-13 is a driver of COVID-19 severity
Published in JCI insight (09-08-2021)“…Immune dysregulation is characteristic of the more severe stages of SARS-CoV-2 infection. Understanding the mechanisms by which the immune system contributes…”
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Generalisable long COVID subtypes: findings from the NIH N3C and RECOVER programmes
Published in EBioMedicine (01-01-2023)“…Stratification of patients with post-acute sequelae of SARS-CoV-2 infection (PASC, or long COVID) would allow precision clinical management strategies…”
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Risk factors associated with post-acute sequelae of SARS-CoV-2: an N3C and NIH RECOVER study
Published in BMC public health (25-10-2023)“…More than one-third of individuals experience post-acute sequelae of SARS-CoV-2 infection (PASC, which includes long-COVID). The objective is to identify risk…”
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Early Empiric Antibiotic Use in Patients Hospitalized With COVID-19: A Retrospective Cohort Study
Published in Critical care medicine (01-09-2023)“…To investigate temporal trends and outcomes associated with early antibiotic prescribing in patients hospitalized with COVID-19. Retrospective…”
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Predictive models of long COVID
Published in EBioMedicine (01-10-2023)“…The cause and symptoms of long COVID are poorly understood. It is challenging to predict whether a given COVID-19 patient will develop long COVID in the…”
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Increased stroke severity and mortality in patients with SARS-CoV-2 infection: An analysis from the N3C database
Published in Journal of stroke and cerebrovascular diseases (01-03-2023)“…Studies from early in the COVID-19 pandemic showed that patients with ischemic stroke and concurrent SARS-CoV-2 infection had increased stroke severity. We…”
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Safety and pharmacokinetics of sodium nitrite in patients with subarachnoid hemorrhage: a phase IIa study
Published in Journal of neurosurgery (01-09-2013)“…Intravenous sodium nitrite has been shown to prevent and reverse cerebral vasospasm in a primate model of subarachnoid hemorrhage (SAH). The present Phase IIA…”
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Insights from an N3C RECOVER EHR-based cohort study characterizing SARS-CoV-2 reinfections and Long COVID
Published in Communications medicine (11-07-2024)“…Background Although the COVID-19 pandemic has persisted for over 3 years, reinfections with SARS-CoV-2 are not well understood. We aim to characterize…”
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185 Stroke and COVID Population: A Health Equity Analysis
Published in Journal of clinical and translational science (01-04-2022)“…OBJECTIVES/GOALS: Observational studies suggest unequal effects of COVID-19 on the population of the U.S. distinguished by race and ethnicity. Our primary…”
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The N3C governance ecosystem: A model socio-technical partnership for the future of collaborative analytics at scale
Published in Journal of clinical and translational science (2023)“…The National COVID Cohort Collaborative (N3C) is a public-private-government partnership established during the Coronavirus pandemic to create a centralized…”
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Finding Long-COVID: temporal topic modeling of electronic health records from the N3C and RECOVER programs
Published in NPJ digital medicine (21-10-2024)“…Post-Acute Sequelae of SARS-CoV-2 infection (PASC), also known as Long-COVID, encompasses a variety of complex and varied outcomes following COVID-19 infection…”
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957: THE ASSOCIATION OF EARLY ANTIBIOTIC USE WITH PROLONGED MECHANICAL VENTILATION IN SEVERE COVID-19
Published in Critical care medicine (01-01-2023)Get full text
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460: EARLY EMPIRIC ANTIBIOTIC USE IN PATIENTS HOSPITALIZED WITH COVID-19: A RETROSPECTIVE COHORT STUDY
Published in Critical care medicine (01-01-2023)Get full text
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Dupilumab use is associated with protection from COVID-19 mortality: A retrospective analysis
Published in Clinical infectious diseases (15-09-2022)“…We previously found that type 2 immunity promotes COVID-19 pathogenesis in a mouse model. To test relevance to human disease we used electronic health record…”
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Characteristics and Outcomes of Stroke Patients with Concurrent SARS-CoV-2 Infection from March 1, 2020 to February 28, 2021: An Analysis from the N3C Database (P11-10.007)
Published in Neurology (03-05-2022)“…Abstract only…”
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Abstract TMP17: Demographics, Characteristics, And Outcomes Of Stroke Patients With Concurrent Sars-cov-2 Infection From March 1, 2020 To February 28, 2020: An Analysis From The N3c Database
Published in Stroke (1970) (01-02-2022)“…BackgroundStudies have shown that patients with ischemic stroke (IS) and concurrent COVID-19 have increased stroke severity. These analyses were limited by use…”
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