Search Results - "Loomans, Cindy J.M."

Expansion of Adult Human Pancreatic Tissue Yields Organoids Harboring Progenitor Cells with Endocrine Differentiation Potential by Loomans, Cindy J.M., Williams Giuliani, Nerys, Balak, Jeetindra, Ringnalda, Femke, van Gurp, Léon, Huch, Meritxell, Boj, Sylvia F., Sato, Toshiro, Kester, Lennart, de Sousa Lopes, Susana M. Chuva, Roost, Matthias S., Bonner-Weir, Susan, Engelse, Marten A., Rabelink, Ton J., Heimberg, Harry, Vries, Robert G.J., van Oudenaarden, Alexander, Carlotti, Françoise, Clevers, Hans, de Koning, Eelco J.P.

“…Generating an unlimited source of human insulin-producing cells is a prerequisite to advance β cell replacement therapy for diabetes. Here, we describe a 3D…”
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Endothelial progenitor cell dysfunction: A novel concept in the pathogenesis of vascular complications of type 1 diabetes by LOOMANS, Cindy J. M, DE KONING, Eelco J. P, STAAL, Frank J. T, ROOKMAAKER, Maarten B, VERSEYDEN, Caroline, DE BOER, Hetty C, VERHAAR, Marianne C, BRAAM, Branko, RABELINK, Ton J, VAN ZONNEVELD, Anton-Jan

“…Type 1 diabetes is associated with reduced vascular repair, as indicated by impaired wound healing and reduced collateral formation in ischemia. Recently,…”
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Ligand-independent recruitment of steroid receptor coactivators to estrogen receptor by cyclin D1 by Zwijsen, R M, Buckle, R S, Hijmans, E M, Loomans, C J, Bernards, R

“…The estrogen receptor (ER) is an important regulator of growth and differentiation of breast epithelium. Transactivation by ER depends on a leucine-rich motif,…”
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Endothelial progenitor cell dysfunction in type 1 diabetes: another consequence of oxidative stress? by Loomans, Cindy J M, De Koning, Eelco J P, Staal, Frank J T, Rabelink, Ton J, Zonneveld, Anton-Jan Van

“…Endothelial progenitor cells (EPC) have been shown to contribute to neovascularization and vascular maintenance and repair in adults. Recently, the concept has…”
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CD34+ Cells Home, Proliferate, and Participate in Capillary Formation, and in Combination With CD34− Cells Enhance Tube Formation in a 3-Dimensional Matrix by Rookmaaker, Maarten B, Verhaar, Marianne C, Loomans, Cindy J.M, Verloop, Robert, Peters, Erna, Westerweel, Peter E, Murohara, Toyoaki, Staal, Frank J.T, van Zonneveld, Anton Jan, Koolwijk, Pieter, Rabelink, Ton J, van Hinsbergh, Victor W.M

“…OBJECTIVE—Emerging evidence suggests that human blood contains bone marrow (BM)-derived endothelial progenitor cells that contribute to postnatal…”
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Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axis by Huch, Meritxell, Bonfanti, Paola, Boj, Sylvia F, Sato, Toshiro, Loomans, Cindy J M, van de Wetering, Marc, Sojoodi, Mozhdeh, Li, Vivian S W, Schuijers, Jurian, Gracanin, Ana, Ringnalda, Femke, Begthel, Harry, Hamer, Karien, Mulder, Joyce, van Es, Johan H, de Koning, Eelco, Vries, Robert G J, Heimberg, Harry, Clevers, Hans

“…Lgr5 marks adult stem cells in multiple adult organs and is a receptor for the Wnt‐agonistic R‐spondins (RSPOs). Intestinal, stomach and liver Lgr5 + stem…”
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Endothelial Progenitor Cell Dysfunction by Loomans, Cindy J.M., de Koning, Eelco J.P., Staal, Frank J.T., Rookmaaker, Maarten B., Verseyden, Caroline, de Boer, Hetty C., Verhaar, Marianne C., Braam, Branko, Rabelink, Ton J., van Zonneveld, Anton-Jan

“…Endothelial Progenitor Cell Dysfunction A Novel Concept in the Pathogenesis of Vascular Complications of Type 1 Diabetes Cindy J.M. Loomans 1 , Eelco J.P. de…”
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Intravital microscopy through an abdominal imaging window reveals a pre-micrometastasis stage during liver metastasis by Ritsma, Laila, Steller, Ernst J A, Beerling, Evelyne, Loomans, Cindy J M, Zomer, Anoek, Gerlach, Carmen, Vrisekoop, Nienke, Seinstra, Daniëlle, van Gurp, Leon, Schäfer, Ronny, Raats, Daniëlle A, de Graaff, Anko, Schumacher, Ton N, de Koning, Eelco J P, Rinkes, Inne H Borel, Kranenburg, Onno, van Rheenen, Jacco

“…Cell dynamics in subcutaneous and breast tumors can be studied through conventional imaging windows with intravital microscopy. By contrast, visualization of…”
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Sequential intravital imaging reveals in vivo dynamics of pancreatic tissue transplanted under the kidney capsule in mice by van Gurp, Léon, Loomans, Cindy J. M., van Krieken, Pim P., Dharmadhikari, Gitanjali, Jansen, Erik, Ringnalda, Femke C. A. S., Beerling, Evelyne, van Rheenen, Jacco, de Koning, Eelco J. P.

“…Aims/hypothesis Dynamic processes in pancreatic tissue are difficult to study. We aimed to develop an intravital imaging method to longitudinally examine…”
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Differentiation of bone marrow-derived endothelial progenitor cells is shifted into a proinflammatory phenotype by hyperglycemia by Loomans, Cindy Jm, van Haperen, Rien, Duijs, Jacques M, Verseyden, Caroline, de Crom, Rini, Leenen, Pieter Jm, Drexhage, Hemmo A, de Boer, Hetty C, de Koning, Eelco Jp, Rabelink, Ton J, Staal, Frank Jt, van Zonneveld, Anton Jan

“…Bone marrow (BM)-derived endothelial progenitor cells (EPC) contribute to vascular maintenance by participating in angiogenesis, re-endothelialization, and…”
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PS2 - 3. The effect of INGAP, FGF7 and a GLP-1R agonist on the differentiation of primary human duct cells towards beta cells by Balak, Jeetindra R.A., Spijker, H. Siebe, Loomans, Cindy J.M., Carlotti, Françoise, de Koning, Eelco J.P.

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Platelets Provide Signals for CD34+ Progenitor Cells to Home to Sites of Vascular Injury by Van Zonneveld, Anton Jan, Verseyden, Caroline, Loomans, Cindy J.M., Rabelink, Ton J., De Boer, Hetty C.

“…Introduction Accumulating evidence indicates that vascular function is modulated by circulating progenitor cells (PCs). Circulating PCs have been shown to…”
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Hemostatic factors such as platelets and fibrin recruit circulating progenitor cells to sites of vascular injury and induce endothelial cell differentiation by de Boer, H.C., Verseyden, Caroline, Loomans, Cindy J.M., Rabelink, Ton J., van Zonneveld, Anton J.

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PS21 - 103. Multipotent pancreatic progenitor cells in 3D culture of human pancreatic ductal tissue: potential relevance for beta cell therapy in Type 1 diabetes by Williams, Nerys A., Loomans, Cindy J.M., van Gurp, Leon C.A., Ringnalda, Femke C.A.S., Sato, Toshiro, Engelse, M.A., Rabelink, A.J., Clevers, Hans, de Koning, Eelco J.P.

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PS18 - 88. Expansion of human beta cell progenitors using a three-dimensional culture system by Loomans, Cindy J.M., Sato, Toshiro, van Gurp, Leon, Ringnalda, Femke, van den Broek, Marloes, Engelse, Marten A., Rabelink, Ton J., Clevers, Hans, de Koning, Eelco J.P.

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Is endothelial progenitor cell dysfunction involved in altered angiogenic processes in patients with hypertension? by Loomans, Cindy J M, Dao, Huy H, van Zonneveld, Anton J, Rabelink, Ton J

“…Hypertension represents one of the most frequent modifiable risk factors for cardiovascular disease (CVD). Despite the arrival of novel antihypertensive drugs…”
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