The Antibacterial and Remineralizing Effects of Biomaterials Combined with DMAHDM Nanocomposite: A Systematic Review

The Antibacterial and Remineralizing Effects of Biomaterials Combined with DMAHDM Nanocomposite: A Systematic Review

Researchers have developed novel nanocomposites that incorporate additional biomaterials with dimethylaminohexadecyl methacrylate (DMAHDM) in order to reduce secondary caries. The aim of this review was to summarize the current literature and assess the synergistic antibacterial and remineralizing e...

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Bibliographic Details
Published in:Materials Vol. 14; no. 7; p. 1688
Main Authors: Clarin, Alison, Ho, Daphne, Soong, Jana, Looi, Cheryl, Ipe, Deepak Samuel, Tadakamadla, Santosh Kumar
Format: Journal Article
Language:English
Published: Switzerland MDPI AG 30-03-2021
MDPI
Subjects:
antibacterial
Bacteria
Bias
Biofilms
Biomedical materials
Bisphenol A
Calcium phosphates
Composite materials
composite resin
Dendrimers
Dental cement
dental materials
Efficiency
Methacryloyloxyethyl phosphorylcholine
Nanocomposites
Nanoparticles
Pathogens
remineralization
Resins
Review
Silver
Statistical analysis
Systematic review
remineralization
composite resin
antibacterial
dental materials
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Summary:Researchers have developed novel nanocomposites that incorporate additional biomaterials with dimethylaminohexadecyl methacrylate (DMAHDM) in order to reduce secondary caries. The aim of this review was to summarize the current literature and assess the synergistic antibacterial and remineralizing effects that may contribute to the prevention of secondary caries. An electronic search was undertaken in MEDLINE using PubMed, Embase, Scopus, Web of Science and Cochrane databases. The initial search identified 954 papers. After the removal of duplicates and screening the titles and abstracts, 15 articles were eligible for this review. The amalgamation of 2-methacryloyloxyethyl phosphorylcholine (MPC) and silver nanoparticles (AgNPs) with DMAHDM resulted in increased antibacterial potency. The addition of nanoparticles of amorphous calcium phosphate (NACP) and polyamidoamine dendrimers (PAMAM) resulted in improved remineralization potential. Further clinical studies need to be planned to explore the antibacterial and remineralizing properties of these novel composites for clinical success.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
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ObjectType-Review-1
ISSN:1996-1944
1996-1944
DOI:10.3390/ma14071688