Search Results - "Loo, Joachim S. C."

Adverse Biophysical Effects of Hydroxyapatite Nanoparticles on Natural Pulmonary Surfactant by Fan, Qihui, Wang, Yi E, Zhao, Xinxin, Loo, Joachim S. C, Zuo, Yi Y

“…Inhaled nanoparticles (NPs) must first interact with the pulmonary surfactant (PS) lining layer that covers the entire internal surface of the respiratory…”
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Collagen–cellulose composite thin films that mimic soft-tissue and allow stem-cell orientation by Steele, Terry W. J., Huang, Charlotte L., Nguyen, Evelyne, Sarig, Udi, Kumar, Saranya, Widjaja, Effendi, Loo, Joachim S. C., Machluf, Marcelle, Boey, Freddy, Vukadinovic, Zlata, Hilfiker, Andreas, Venkatraman, Subbu S.

“…Mechanical properties of collagen films are less than ideal for biomaterial development towards musculoskeletal repair or cardiovascular applications. Herein,…”
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Understanding Fundamentals and Reaction Mechanisms of Electrode Materials for Na‐Ion Batteries by Yu, Linghui, Wang, Luyuan Paul, Liao, Hanbin, Wang, Jingxian, Feng, Zhenxing, Lev, Ovadia, Loo, Joachim S. C., Sougrati, Moulay Tahar, Xu, Zhichuan J.

“…Development of efficient, affordable, and sustainable energy storage technologies has become an area of interest due to the worsening environmental issues and…”
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Achieving High Electrocatalytic Efficiency on Copper: A Low-Cost Alternative to Platinum for Hydrogen Generation in Water by Zhao, Jian, Tran, Phong D, Chen, Yang, Loo, Joachim S. C, Barber, James, Xu, Zhichuan J

“…A phosphate mediated (photo)­electro-reduction process has been developed to activate cuprous oxide (Cu2O) to copper–cuprous oxide (Cu/Cu2O) for high efficient…”
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High-throughput screening of PLGA thin films utilizing hydrophobic fluorescent dyes for hydrophobic drug compounds by Steele, Terry W J, Huang, Charlotte L, Kumar, Saranya, Widjaja, Effendi, Chiang Boey, Freddy Yin, Loo, Joachim S C, Venkatraman, Subbu S

“…Hydrophobic, antirestenotic drugs such as paclitaxel (PCTX) and rapamycin are often incorporated into thin film coatings for local delivery using implantable…”
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The role of the tumor suppressor p53 pathway in the cellular DNA damage response to zinc oxide nanoparticles by Ng, Kee Woei, Khoo, Stella P.K, Heng, Boon Chin, Setyawati, Magdiel I, Tan, Eng Chok, Zhao, Xinxin, Xiong, Sijing, Fang, Wanru, Leong, David T, Loo, Joachim S.C

“…Abstract In this paper, we explored how ZnO nanoparticles cross-interact with a critical tumor suppressive pathway centered around p53, which is one of the…”
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Development of a Magnetic 3D Spheroid Platform with Potential Application for High-Throughput Drug Screening by Guo, Wei Mei, Loh, Xian Jun, Tan, Ern Yu, Loo, Joachim S. C, Ho, Vincent H. B

“…Three-dimensional (3D) cell culture has become increasingly adopted as a more accurate model of the complex in vivo microenvironment compared to conventional…”
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Controlled release of sirolimus from a multilayered PLGA stent matrix by Wang, Xintong, Venkatraman, Subbu S., Boey, Freddy Y.C., Loo, Joachim S.C., Tan, Lay Poh

“…The release of sirolimus from a bi-layer biodegradable polymeric film is reported in this study. Approved drug-eluting metal stents use a thin polymer coating…”
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Modulating drug release from poly(lactic-co-glycolic acid) thin films through terminal end-groups and molecular weight by Huang, Charlotte L., Kumar, Saranya, Tan, John J.Z., Boey, Freddy Y.C., Venkatraman, Subbu S., Steele, Terry W.J., Loo, Joachim S.C.

“…Biodegradable PLGA is commonly employed for controlled drug release on the order of weeks to months. Hydrophobic drugs distribute homogeneously in PLGA, but…”
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The effect of polyethylene glycol structure on paclitaxel drug release and mechanical properties of PLGA thin films by Steele, Terry W.J., Huang, Charlotte L., Widjaja, Effendi, Boey, Freddy Y.C., Loo, Joachim S.C., Venkatraman, Subbu S.

“…Thin films of poly(lactic acid-co-glycolic acid) (PLGA) incorporating paclitaxel typically have slow release rates of paclitaxel of the order of 1 μg day −1 cm…”
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Use of Raman Microscopy and Multivariate Data Analysis to Observe the Biomimetic Growth of Carbonated Hydroxyapatite on Bioactive Glass by Seah, Regina K. H, Garland, Marc, Loo, Joachim S. C, Widjaja, Effendi

“…In the present contribution, the biomimetic growth of carbonated hydroxyapatite (HA) on bioactive glass were investigated by Raman microscopy. Bioactive glass…”
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Naphthoquinone glycosides for bioelectroanalytical enumeration of the faecal indicator Escherichia coli by Hinks, Jamie, Han, Evelina J. Y., Wang, Victor B., Seviour, Thomas W., Marsili, Enrico, Loo, Joachim S. C., Wuertz, Stefan

“…Summary Microbial water quality monitoring for the presence of faecal indicator bacteria (FIB) is a mandatory activity in many countries and is key in public…”
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High Throughput Screening of Valganciclovir in Acidic Microenvironments of Polyester Thin Films by Schaller, Teilo, Wenner, Tobias, Agrawal, Rupesh, Teoh, Stephen, Phua, Li Ting, Loo, Joachim S C, Steele, Terry W J

“…Ganciclovir and valganciclor are antiviral agents used for the treatment of cytomegalovirus retinitis. The conventional method for administering ganciclovir in…”
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Manipulating Magnetic 3D Spheroids in Hanging Drops for Applications in Tissue Engineering and Drug Screening by Ho, Vincent H. B., Guo, Wei Mei, Huang, Charlotte L., Ho, Shu Fen, Chaw, Su Yin, Tan, Ern Yu, Ng, Kee Woei, Loo, Joachim S.C.

“…Magnetic spheroid manipulation can be carried out in hanging drops to generate distinctly structured heterotypic microtissues through sequential addition of…”
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Increasing Hydrophobicity of Nanoparticles Intensifies Lung Surfactant Film Inhibition and Particle Retention by Valle, Russell P, Huang, Charlotte Liwen, Loo, Joachim S. C, Zuo, Yi Y

“…Polymeric nanoparticles (NPs) have had much focus on their ability to penetrate deep pulmonary structures as potential drug carriers. However, research on the…”
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Drug-eluting scaffolds for bone and cartilage regeneration by Huang, Charlotte L., Lee, Wei Li, Loo, Joachim S.C.

“…•Tissue repair involves intricate mimicry of biological signals.•Developments in tissue regeneration have been centered on the diamond concept.•Delivery…”
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Operando Investigation of Mn3O4+δ Co-catalyst on Fe2O3 Photoanode: Manganese-Valency-Determined Enhancement at Varied Potentials by Liu, Ying, Wei, Chao, Ngaw, Chee Keong, Zhou, Ye, Sun, Shengnan, Xi, Shibo, Du, Yonghua, Loo, Joachim S. C, Ager, Joel W, Xu, Zhichuan J

“…The development of efficient catalysts containing earth-abundant elements for the oxygen evolution reaction (OER) in photoelectrochemical (PEC) systems is…”
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Exploiting the high-affinity phosphonate–hydroxyapatite nanoparticle interaction for delivery of radiation and drugs by Ong, Hooi Tin, Loo, Joachim S. C., Boey, Freddy Y. C., Russell, Stephen J., Ma, Jan, Peng, Kah-Whye

“…Hydroxyapatite is biocompatible and used in various biomedical applications. Here, we generated hydroxyapatite nanoparticles (HNPs) of various sizes…”
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Novel gradient casting method provides high-throughput assessment of blended polyester poly(lactic-co-glycolic acid) thin films for parameter optimization by Steele, Terry W.J., Huang, Charlotte L., Kumar, Saranya, Irvine, Scott, Boey, Freddy Yin Chiang, Loo, Joachim S.C., Venkatraman, Subbu S.

“…Pure polymer films cannot meet the diverse range of controlled release and material properties demanded for the fabrication of medical implants or other…”
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Tuning drug release in polyester thin films: terminal end-groups determine specific rates of additive-free controlled drug release by Steele, Terry W J, Huang, Charlotte L, Kumar, Saranya, Iskandar, Aneesa, Baoxin, Aw, Chiang Boey, Freddy Yin, Loo, Joachim S C, Venkatraman, Subbu S

“…Modulating the drug release from polyester matrices independently of material properties would be beneficial to those designing biodegradable medical implants,…”
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