Search Results - "Loo, D. Maroeska W. M. te"
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Quality of Active versus Spontaneous Reporting of Adverse Drug Reactions in Pediatric Patients: Relevance for Pharmacovigilance and Knowledge in Pediatric Medical Care
Published in Pharmaceuticals (Basel, Switzerland) (01-09-2022)“…For drug safety in pediatric patients, knowledge about adverse drug reactions (ADRs) is essential to balance benefits and risks, especially because of the high…”
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TropicALL study: Thromboprophylaxis in Children treated for Acute Lymphoblastic Leukemia with Low-molecular-weight heparin: a multicenter randomized controlled trial
Published in BMC pediatrics (10-05-2017)“…Venous thromboembolism (VTE) is a common and severe complication during treatment of acute lymphoblastic leukemia (ALL). An important cause is the intensive…”
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GNA11‐mutated Sturge–Weber syndrome has distinct neurological and dermatological features
Published in European journal of neurology (01-10-2022)“…Background and purpose Sturge–Weber syndrome (SWS) is a neurocutaneous disorder characterized by clinical manifestations involving the brain, eye and skin. SWS…”
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Health-related quality of life in children with congenital vascular malformations
Published in European journal of pediatrics (01-11-2023)“…A cross-sectional study was performed to evaluate health-related quality of life (HRQOL) in children with congenital vascular malformations (CVM) and to…”
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Patients with Congenital Low-Flow Vascular Malformation Treated with Low Dose Sirolimus
Published in Advances in therapy (01-06-2021)“…Introduction Patients with congenital vascular malformations often suffer from an impaired quality of life (QoL) because of pain and functional disabilities…”
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Analysis of Reporting Adverse Drug Reactions in Paediatric Patients in a University Hospital in the Netherlands
Published in Paediatric drugs (01-08-2020)“…Aims The risk to develop adverse drug reactions (ADRs) is high for paediatric patients. This is, amongst other reasons, due to the inevitable use of off-label…”
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Analysis of Drug Metabolizing Gene Panel in Osteosarcoma Patients Identifies Association Between Variants in SULT1E1, CYP2B6 and CYP4F8 and Methotrexate Levels and Toxicities
Published in Frontiers in pharmacology (12-08-2020)“…High-dose methotrexate is a cornerstone agent in the chemotherapeutic treatment of patients with osteosarcoma. However, patients often develop…”
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Genome-Wide Analyses of Nephrotoxicity in Platinum-Treated Cancer Patients Identify Association with Genetic Variant in RBMS3 and Acute Kidney Injury
Published in Journal of personalized medicine (28-05-2022)“…Nephrotoxicity is a common and dose-limiting side effect of platinum compounds, which often manifests as acute kidney injury or hypomagnesemia. This study…”
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Magnitude and relevance of change in health-related quality of life in patients with vascular malformations treated with sirolimus
Published in Frontiers in medicine (20-04-2023)“…Vascular malformations are rare congenital anomalies of the vascular system, which can involve the capillaries, veins, arteries, lymphatics, or a combination…”
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Lack of specific binding of Shiga-like toxin (verocytotoxin) and non-specific interaction of Shiga-like toxin 2 antibody with human polymorphonuclear leucocytes
Published in Nephrology, dialysis, transplantation (01-03-2007)“…Background. After gastrointestinal infection with Shiga-like toxin (Stx) producing Escherichia coli, the toxin is transported from the intestine to the renal…”
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The role of germline variants in chemotherapy outcome in brain tumors: a systematic review of pharmacogenetic studies
Published in Pharmacogenomics (01-04-2017)“…This systematic review provides an overview of publications concerning pharmacogenetic research in pediatric patients with medulloblastoma and low-grade…”
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Is there a role for the MTHFR 677C>T and 1298A>C polymorphisms in methotrexate-induced liver toxicity?
Published in Pharmacogenomics (01-08-2014)Get more information
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Age as prognostic factor in patients with osteosarcoma
Published in Bone (New York, N.Y.) (01-12-2011)“…Abstract Age at diagnosis is a well known prognostic factor in many different malignancies; its significance for patients with osteosarcoma is however…”
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Survival Trends and Long-Term Toxicity in Pediatric Patients with Osteosarcoma
Published in Sarcoma (2012)“…Background. This study was conducted to investigate the clinical characteristics and treatment results of osteosarcoma in pediatric patients during the past 30…”
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A prospective study on drug monitoring of PEGasparaginase and Erwinia asparaginase and asparaginase antibodies in pediatric acute lymphoblastic leukemia
Published in Blood (27-03-2014)“…This study prospectively analyzed the efficacy of very prolonged courses of pegylated Escherichia coli asparaginase (PEGasparaginase) and Erwinia asparaginase…”
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Prognostic Significance of Blasts in the Cerebrospinal Fluid Without Pleiocytosis or a Traumatic Lumbar Puncture in Children With Acute Lymphoblastic Leukemia: Experience of the Dutch Childhood Oncology Group
Published in Journal of clinical oncology (20-05-2006)“…To determine the significance of blasts in the CSF without pleiocytosis and a traumatic lumbar puncture in children with acute lymphoblastic leukemia (ALL). We…”
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Effective low–dose sirolimus regimen for kaposiform haemangioendothelioma with Kasabach–Merritt phenomenon in young infants
Published in British journal of clinical pharmacology (01-06-2022)“…Aims Management of kaposiform haemangioendotheliomas (KHE) with Kasabach–Merritt phenomenon is challenging in young infants who are subjected to developmental…”
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Contribution of common and rare genetic variants in CEP72 on vincristine‐induced peripheral neuropathy in brain tumour patients
Published in British journal of clinical pharmacology (01-07-2022)“…Aims Studies implicated a role for a genetic variant in CEP72 in vincristine‐induced peripheral neuropathy. This study aims to evaluate this association in a…”
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Clinical differences in sirolimus treatment with low target levels between children and adults with vascular malformations – A nationwide trial
Published in Clinical and translational science (01-05-2023)“…The clinical presentation of patients with slow‐flow vascular malformations is very heterogeneous. High clinical burden and subsequent reduced health‐related…”
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