Search Results - "Lonser, Russell"

Research in Neurological Surgery by Lonser, Russell R

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Cushing's disease: pathobiology, diagnosis, and management by Lonser, Russell R, Nieman, Lynnette, Oldfield, Edward H

“…Cushing's disease (CD) is the result of excess secretion of adrenocorticotropic hormone (ACTH) by a benign monoclonal pituitary adenoma. The excessive…”
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Management of hormone-secreting pituitary adenomas by Mehta, Gautam U, Lonser, Russell R

“…Pituitary adenomas are one of the most common primary central nervous system tumors and have an estimated prevalence of 17%. Approximately half of pituitary…”
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Von Hippel-Lindau disease by Chittiboina, Prashant, Lonser, Russell R

“…von Hippel-Lindau (VHL) disease is an inheritable condition with an incidence of 1 in 36000 live births. Individuals with VHL develop benign and malignant…”
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Direct Convective Delivery for Nervous System Gene Therapy by Elder, James Bradley, Lonser, Russell R.

“…Convection-enhanced delivery for central nervous system gene therapy is an emerging treatment strategy to modify the course of previously untreatable or…”
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Convection-enhanced delivery to the central nervous system by Lonser, Russell R, Sarntinoranont, Malisa, Morrison, Paul F, Oldfield, Edward H

“…Convection-enhanced delivery (CED) is a bulk flow-driven process. Its properties permit direct, homogeneous, targeted perfusion of CNS regions with putative…”
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Gene therapy for aromatic L-amino acid decarboxylase deficiency by MR-guided direct delivery of AAV2-AADC to midbrain dopaminergic neurons by Pearson, Toni S., Gupta, Nalin, San Sebastian, Waldy, Imamura-Ching, Jill, Viehoever, Amy, Grijalvo-Perez, Ana, Fay, Alex J., Seth, Neha, Lundy, Shannon M., Seo, Youngho, Pampaloni, Miguel, Hyland, Keith, Smith, Erin, de Oliveira Barbosa, Gardenia, Heathcock, Jill C., Minnema, Amy, Lonser, Russell, Elder, J. Bradley, Leonard, Jeffrey, Larson, Paul, Bankiewicz, Krystof S.

“…Aromatic L-amino acid decarboxylase (AADC) deficiency is a rare genetic disorder characterized by deficient synthesis of dopamine and serotonin. It presents in…”
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Adjuvant convection-enhanced delivery for the treatment of brain tumors by Kreatsoulas, Daniel, Damante, Mark, Cua, Santino, Lonser, Russell R.

“…Background Malignant gliomas are a therapeutic challenge and remain nearly uniformly fatal. While new targeted chemotherapeutic agentsagainst malignant glioma…”
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Phase I trial of intracerebral convection-enhanced delivery of carboplatin for treatment of recurrent high-grade gliomas by Wang, Joshua L, Barth, Rolf F, Cavaliere, Robert, Puduvalli, Vinay K, Giglio, Pierre, Lonser, Russell R, Elder, J Bradley

“…Carboplatin is a potent cytoreductive agent for a variety of solid tumors. However, when delivered systemically, clinical efficacy for the treatment of high…”
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Obituary. Edward H. Oldfield, MD, 1947-2017 by Lonser, Russell R

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Advance, Adapt, Achieve: The 2016 Congress of Neurological Surgeons Presidential Address by Lonser, Russell R.

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History of biological, mechanistic, and clinical understanding of concussion by Eaton, Ryan G, Lonser, Russell R

“…The history behind the biological, mechanistic, and clinical insights into concussion provides awareness of the current understanding and future areas for…”
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Real-Time Magnetic Resonance Imaging During Convective Gene Therapy Perfusion of the Brain by Akhter, Asad S, Bankiewicz, Krzysztof S, Lonser, Russell R

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Direct convective delivery of adeno-associated virus gene therapy for treatment of neurological disorders by Lonser, Russell R, Akhter, Asad S, Zabek, Mirosław, Elder, J Bradley, Bankiewicz, Krystof S

“…Molecular biological insights have led to a fundamental understanding of the underlying genomic mechanisms of nervous system disease. These findings have…”
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Controversies in Neurosurgery by Lonser, Russell R., Resnick, Daniel K.

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Neurofibromatosis type 2 by Asthagiri, Ashok R, Dr, Parry, Dilys M, PhD, Butman, John A, MD, Kim, H Jeffrey, MD, Tsilou, Ekaterini T, MD, Zhuang, Zhengping, Prof, Lonser, Russell R, Prof

“…Summary Neurofibromatosis type 2 is an autosomal-dominant multiple neoplasia syndrome that results from mutations in the NF2 tumour suppressor gene located on…”
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Characterization of the blood-brain barrier of metastatic and primary malignant neoplasms by Nduom, Edjah K, Yang, Chunzhang, Merrill, Marsha J, Zhuang, Zhengping, Lonser, Russell R

“…The astrocytic contribution to the blood-brain barrier (BBB) in metastatic and primary malignant brain tumors is not well understood. To better understand the…”
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Trial of magnetic resonance–guided putaminal gene therapy for advanced Parkinson's disease by Heiss, John D., Lungu, Codrin, Hammoud, Dima A., Herscovitch, Peter, Ehrlich, Debra J., Argersinger, Davis P., Sinharay, Sanhita, Scott, Gretchen, Wu, Tianxia, Federoff, Howard J., Zaghloul, Kareem A., Hallett, Mark, Lonser, Russell R., Bankiewicz, Krystof S.

“…Objective To investigate the safety and tolerability of convection‐enhanced delivery of an adeno‐associated virus, serotype‐2 vector carrying glial cell…”
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Creation of a comprehensive training and career development approach to increase the number of neurosurgeons supported by National Institutes of Health funding by Lonser, Russell R, Smith, Luke G F, Tennekoon, Michael, Rezai-Zadeh, Kavon P, Ojemann, Jeffrey G, Korn, Stephen J

“…To increase the number of independent National Institutes of Health (NIH)-funded neurosurgeons and to enhance neurosurgery research, the National Institute of…”
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Imaging of Convective Drug Delivery in the Nervous System by Lonser, Russell R.

“…Convection-enhanced delivery permits the direct homogeneous delivery of small- and large-molecular-weight putative therapeutics to the nervous system in a…”
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