Search Results - "Longway, Gabriella"

Abstract 3679: DNAJB1-PRKACA fusion in fibrolamellar hepatocellular carcinoma induces glutamine addiction and an immunosuppressive tumor microenvironment by Kamdar, Zeal, Lopez-Vidal, Tamara, Howe, Kathryn, Munjal, Kabeer, Saeed, Ali, Zabransky, Daniel, Shu, Daniel, Longway, Gabriella, Kartalia, Emma, Leatherman, James, Mohan, Aditya, Khare, Pratik, Zhang, Cissy, Le, Anne, Pearce, Erika, Furth, Mark, Baretti, Marina, Leone, Robert, Jaffee, Elizabeth, Yarchoan, Mark

“…Fibrolamellar hepatocellular carcinoma (FLC) is a rare and often lethal form of liver cancer that primarily affects children and young adults. A fusion between…”
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Abstract 1170: An off-the-shelf vaccine activates mutant KRAS-specific T cells in patients with resected pancreatic cancer by Huff, Amanda L., Girgis, Alex, Haldar, Saurav D., Davis-Marcisak, Emily, Heumann, Thatcher, Longway, Gabriella, Andaloori, Lalitya, Hernandez, Alexei, Konig, Maximilian F., Mog, Brian, Danilova, Ludmila, Kagohara, Luciane T., Nauroth, Julie M., Thomas, Amy M., Fertig, Elana J., Ho, Won Jin, Jaffee, Elizabeth M., Azad, Nilofer, Zaidi, Neeha

“…Background: Oncogenic mutations in KRAS (mKRAS) are expressed in up to 90% of pancreatic ductal adenocarcinomas (PDAC) therefore representing a promising…”
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CD4 T cell-activating neoantigens enhance personalized cancer vaccine efficacy by Huff, Amanda L, Longway, Gabriella, Mitchell, Jacob T, Andaloori, Lalitya, Davis-Marcisak, Emily, Chen, Fangluo, Lyman, Melissa R, Wang, Rulin, Mathew, Jocelyn, Barrett, Benjamin, Rahman, Sabahat, Leatherman, James, Yarchoan, Mark, Azad, Nilofer S, Yegnasubramanian, Srinivasan, Kagohara, Luciane T, Fertig, Elana J, Jaffee, Elizabeth M, Armstrong, Todd D, Zaidi, Neeha

“…Personalized cancer vaccines aim to activate and expand cytotoxic antitumor CD8+ T cells to recognize and kill tumor cells. However, the role of CD4+ T cell…”
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Abstract IA013: Intercepting pancreatic cancer development with mutant KRAS-targeted immunotherapy by Zaidi, Neeha, Huff, Amanda, Marcisak-Davis, Emily, Haldar, Daniel, Heumann, Thatcher, Konig, Max, Mog, Brian, Montagne, Janelle, Longway, Gabriella, Andaloori, Lalitya, Lyman, Melissa, Danilova, Ludmila, Nauroth, Julie, Kagohara, Luciane, Fertig, Elana, Azad, Nilo, Jaffee, Elizabeth

“…The evolution of pancreatic ductal adenocarcinoma (PDAC) from tumor initiation to metastases requires years to decades, providing a window of opportunity for…”
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Abstract B032: Spatial proteomics and transcriptomics reveal early immune cell organization in human pancreatic intraepithelial neoplasia by Lyman, Melissa R., Mitchell, Jacob T., Kagohara, Luciane T., Huff, Amanda L., Haldar, Daniel, Shin, Sarah, Guinn, Samantha, Barrett, Benjamin, Longway, Gabriella, Hernandez, Alexei, Coyne, Erin, Yuan, Xuan, Andaloori, Lalitya, Lai, Jiaying, Liu, YunZhou, Karchin, Rachel, Gupta, Anuj, Kiemen, Ashley, Forjaz, André, Wirtz, Denis, Wu, Pei-Hsun, Deshpande, Atul, Armstrong, Todd, Azad, Nilofer S., Thompson, Elizabeth, Anders, Robert, Ho, Won Jin, Jaffee, Elizabeth, Fertig, Elana, Zaidi, Neeha

“…A common precursor of pancreatic adenocarcinoma (PDAC) are microscopic lesions, termed pancreatic intraepithelial neoplasia (or PanIN). These lesions are…”
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Abstract LB197: A pooled mutant KRAS peptide vaccine activates polyfunctional T cell responses in patients with resected pancreatic cancer by Huff, Amanda L., Haldar, Saurav D., Davis-Marcisak, Emily, Heumann, Thatcher, Longway, Gabriella, Hernandez, Alexei, Konig, Maximillian F., Mog, Brian, Danilova, Ludmila, Kagohara, Luciane, Nauroth, Julie M., Thomas, Amy M., Fertig, Elana J., Ho, Won Jin, Jaffee, Elizabeth M., Azad, Nilo, Zaidi, Neeha

“…Background: Oncogenic mutations in KRAS are expressed in up to 90% of pancreatic ductal adenocarcinomas (PDAC). Vaccination against mutant KRAS (mKRAS) is thus…”
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Abstract 2873: Evolution of immune cell composition and functionality as pancreatic intraepithelial neoplasia progresses to pancreatic ductal adenocarcinoma by Lyman, Melissa R., Mitchell, Jacob T., Kagohara, Luciane T., Barrett, Benjamin, Huff, Amanda, Shin, Sarah, Longway, Gabriella, Gupta, Anuj, Andaloori, Lalitya, Armstrong, Todd D., Haldar, Daniel, Anders, Robert, Thompson, Elizabeth, Azad, Nilo, Ho, Won Jin, Jaffee, Elizabeth, Fertig, Elana J., Zaidi, Neeha

“…Pancreatic ductal adenocarcinoma (PDAC) is most often diagnosed at an advanced stage. Newly diagnosed patients therefore have a dismal five-year survival rate…”
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