Search Results - "Longtine, Mark S."

Hypoxia Induces Autophagy in Primary Human Trophoblasts by Chen, Baosheng, Longtine, Mark S, Nelson, D. Michael

“…Autophagy is a highly regulated and dynamic process that maintains cellular homeostasis and plays a prosurvival role in most cells. Although hypoxia has been…”
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The human placental sexome differs between trophoblast epithelium and villous vessel endothelium by Cvitic, Silvija, Longtine, Mark S, Hackl, Hubert, Wagner, Karin, Nelson, Michael D, Desoye, Gernot, Hiden, Ursula

“…Molecular mechanisms underlying sexual dimorphism in mammals, fetal sex influences on intrauterine development, and the sex-biased susceptibility for selected…”
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Pomegranate juice and punicalagin attenuate oxidative stress and apoptosis in human placenta and in human placental trophoblasts by Chen, Baosheng, Tuuli, Methodius G, Longtine, Mark S, Shin, Joong Sik, Lawrence, Russell, Inder, Terrie, Michael Nelson, D

“…The human placenta is key to pregnancy outcome, and the elevated oxidative stress present in many complicated pregnancies contributes to placental dysfunction…”
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Hypoxia downregulates p53 but induces apoptosis and enhances expression of BAD in cultures of human syncytiotrophoblasts by Chen, Baosheng, Longtine, Mark S, Sadovsky, Yoel, Nelson, D Michael

“…Hypoxia is commonly assigned a role in the placental dysfunction characteristic of preeclampsia and intrauterine growth restriction. We previously showed that…”
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Prostate Cancer Theranostics - An Overview by Abou, Diane, Benabdallah, Nadia, Jiang, Wen, Peng, Lu, Zhang, Hanwen, Villmer, Alexandria, Longtine, Mark S., Thorek, Daniel L. J.

“…Metastatic prostate cancer is incurable, and novel methods to detect the disease earlier and to direct definitive treatment are needed. Molecularly specific…”
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Caspase-mediated apoptosis of trophoblasts in term human placental villi is restricted to cytotrophoblasts and absent from the multinucleated syncytiotrophoblast by Longtine, Mark S, Chen, Baosheng, Odibo, Anthony O, Zhong, Yan, Nelson, D Michael

“…Human placental villi are surfaced by a multinucleated and terminally differentiated epithelium, the syncytiotrophoblast, with a subjacent layer of…”
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Regulation of septin organization and function in yeast by Longtine, Mark S, Bi, Erfei

“…Septins are a conserved eukaryotic family of GTP-binding filament-forming proteins with functions in cytokinesis and other processes. In the budding yeast…”
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Calcitriol regulates immune genes CD14 and CD180 to modulate LPS responses in human trophoblasts by Longtine, Mark S, Cvitic, Silvija, Colvin, Bryanne N, Chen, Baosheng, Desoye, Gernot, Nelson, D Michael

“…We assessed the response of primary cultures of placental villous mononucleated trophoblasts and multinucleated syncytiotrophoblast to calcitriol, the most…”
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Two Distinct Myeloid Subsets at the Term Human Fetal-Maternal Interface by Costa, Maria Laura, Robinette, Michelle L, Bugatti, Mattia, Longtine, Mark S, Colvin, Bryanne N, Lantelme, Erica, Vermi, William, Colonna, Marco, Nelson, D Michael, Cella, Marina

“…During pregnancy, immune cells infiltrate the placenta at different stages of fetal development. NK cells and macrophages are the most predominant cell types…”
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Role of Nucleotide Binding in Septin-Septin Interactions and Septin Localization in Saccharomyces cerevisiae by Nagaraj, Satish, Rajendran, Ashok, Jackson, Charles E., Longtine, Mark S.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Bni1p, a Yeast Formin Linking Cdc42p and the Actin Cytoskeleton During Polarized Morphogenesis by Evangelista, Marie, Blundell, Kelly, Longtine, Mark S., Chow, Clinton J., Adames, Neil, Pringle, John R., Peter, Matthias, Boone, Charles

“…The Saccharomyces cerevisiae BNI1 gene product (Bni1p) is a member of the formin family of proteins, which participate in cell polarization, cytokinesis, and…”
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Role of the yeast Gin4p protein kinase in septin assembly and the relationship between septin assembly and septin function by Longtine, M.S. (University of North Carolina, Chapel Hill, NC.), Fares, H, Pringle, J.R

“…To identify septin-interacting proteins in Saccharomyces cerevisiae, we screened for mutations that are synthetically lethal with a cdc12 septin mutation. One…”
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Punicalagin promotes autophagy to protect primary human syncytiotrophoblasts from apoptosis by Wang, Ying, Chen, Baosheng, Longtine, Mark S, Nelson, D Michael

“…Punicalagin is a prominent polyphenol in pomegranate juice that protects cultured syncytiotrophoblasts from stress-induced apoptosis. Here, we test the…”
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Punicalagin, a polyphenol in pomegranate juice, downregulates p53 and attenuates hypoxia-induced apoptosis in cultured human placental syncytiotrophoblasts by Chen, Baosheng, Longtine, Mark S, Nelson, D Michael

“…Oxidative stress is associated with placental dysfunction and suboptimal pregnancy outcomes. Therapeutic interventions to limit placental injury from oxidative…”
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Cure of Disseminated Human Lymphoma with [ 225 Ac]Ac-Ofatumumab in a Preclinical Model by Longtine, Mark S, Shim, Kyuhwan, Hoegger, Mark J, Benabdallah, Nadia, Abou, Diane S, Thorek, Daniel L J, Wahl, Richard L

“…Immunotherapies that target the CD20 protein expressed on most non-Hodgkin lymphoma cells have improved clinical outcomes, but relapse is common. We prepared…”
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Placental dysfunction and fetal programming: the importance of placental size, shape, histopathology, and molecular composition by Longtine, Mark S, Nelson, D Michael

“…Normal function of the placenta is pivotal for optimal fetal growth and development. Fetal programming commonly is associated with placental dysfunction that…”
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Oleate attenuates palmitate-induced endoplasmic reticulum stress and apoptosis in placental trophoblasts by Colvin, Bryanne N, Longtine, Mark S, Chen, Baosheng, Costa, Maria Laura, Nelson, D Michael

“…Pre-pregnancy obesity is increasingly common and predisposes pregnant women and offspring to gestational diabetes, pre-eclampsia, fetal growth abnormalities…”
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Cure of Disseminated Human Lymphoma with [ 177 Lu]Lu-Ofatumumab in a Preclinical Model by Shim, Kyuhwan, Longtine, Mark S, Abou, Diane S, Hoegger, Mark J, Laforest, Richard S, Thorek, Daniel L J, Wahl, Richard L

“…Although immunotherapies that target CD20 on most non-Hodgkin lymphoma (NHL) cells have improved patient outcomes, current therapies are inadequate because…”
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Bioluminescent Tumor Signal Is Mouse Strain and Pelt Color Dependent: Experience in a Disseminated Lymphoma Model by Hoegger, Mark J., Longtine, Mark S., Shim, Kyuhwan, Wahl, Richard L.

“…Background Many preclinical cancer studies use mice with varied phenotypes to monitor tumor treatment. We compared survival and optical imaging characteristics…”
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Bni5p, a Septin-Interacting Protein, Is Required for Normal Septin Function and Cytokinesis in Saccharomyces cerevisiae by Lee, Philip R., Song, Sukgil, Ro, Hyeon-Su, Park, Chong J., Lippincott, John, Li, Rong, Pringle, John R., De Virgilio, Claudio, Longtine, Mark S., Lee, Kyung S.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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