Search Results - "Longshore, John W."

Programmed Death-Ligand 1 Immunohistochemistry Testing: A Review of Analytical Assays and Clinical Implementation in Non-Small-Cell Lung Cancer by Büttner, Reinhard, Gosney, John R, Skov, Birgit Guldhammer, Adam, Julien, Motoi, Noriko, Bloom, Kenneth J, Dietel, Manfred, Longshore, John W, López-Ríos, Fernando, Penault-Llorca, Frédérique, Viale, Giuseppe, Wotherspoon, Andrew C, Kerr, Keith M, Tsao, Ming-Sound

“…Purpose Three programmed death-1/programmed death-ligand 1 (PD-L1) inhibitors are currently approved for treatment of non-small-cell lung cancer (NSCLC)…”
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The Promises and Challenges of Tumor Mutation Burden as an Immunotherapy Biomarker: A Perspective from the International Association for the Study of Lung Cancer Pathology Committee by Sholl, Lynette M, Hirsch, Fred R, Hwang, David, Botling, Johan, Lopez-Rios, Fernando, Bubendorf, Lukas, Mino-Kenudson, Mari, Roden, Anja C, Beasley, Mary Beth, Borczuk, Alain, Brambilla, Elisabeth, Chen, Gang, Chou, Teh-Ying, Chung, Jin-Haeng, Cooper, Wendy A, Dacic, Sanja, Lantuejoul, Sylvie, Jain, Deepali, Lin, Dongmei, Minami, Yuko, Moreira, Andre, Nicholson, Andrew G, Noguchi, Masayuki, Papotti, Mauro, Pelosi, Giuseppe, Poleri, Claudia, Rekhtman, Natasha, Tsao, Ming-Sound, Thunnissen, Erik, Travis, William, Yatabe, Yasushi, Yoshida, Akihiko, Daigneault, Jillian B, Zehir, Ahmet, Peters, Solange, Wistuba, Ignacio I, Kerr, Keith M, Longshore, John W

“…Immune checkpoint inhibitor (ICI) therapies have revolutionized the management of patients with NSCLC and have led to unprecedented improvements in response…”
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Implementing TMB measurement in clinical practice: considerations on assay requirements by Büttner, Reinhard, Longshore, John W, López-Ríos, Fernando, Merkelbach-Bruse, Sabine, Normanno, Nicola, Rouleau, Etienne, Penault-Llorca, Frédérique

“…Clinical evidence demonstrates that treatment with immune checkpoint inhibitor immunotherapy agents can have considerable benefit across multiple tumours…”
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Performance of the cobas EZH2 mutation test on clinical samples from non-Hodgkin lymphoma patients by Shyu, Johnny Y, Schlag, Peter A, Karwowska, Sylwia M, Manohar, Chitra F, Truong, Huan M, Longshore, John W, Zhang, Guili

“…To present the technical verification and clinical validation of the companion diagnostic assay, cobas® EZH2 Mutation Test (cobas EZH2 Test), targeting…”
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Accurate detection of BRAF p.V600E mutations in challenging melanoma specimens requires stringent immunohistochemistry scoring criteria or sensitive molecular assays by Fisher, Kevin E., MD, PhD, Cohen, Cynthia, MD, Siddiqui, Momin T., MD, Palma, John F., PhD, Lipford, Edward H., MD, Longshore, John W., PhD

“…Summary Malignant melanoma patients require BRAF mutation testing prior to initiating BRAF inhibitor therapy. Molecular testing remains the diagnostic gold…”
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Molecular Testing for Treatment of Metastatic Non‐Small Cell Lung Cancer: How to Implement Evidence‐Based Recommendations by Levy, Benjamin P., Chioda, Marc D., Herndon, Dana, Longshore, John W., Mohamed, Mohamed, Ou, Sai‐Hong Ignatius, Reynolds, Craig, Singh, Jaspal, Wistuba, Ignacio I., Bunn, Paul A., Hirsch, Fred R.

“…The recent discovery of relevant biomarkers has reshaped our approach to therapy selection for patients with non‐small cell lung cancer. The unprecedented…”
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Point: Comprehensive Molecular Testing Functions Best in a Consolidated Model by Longshore, John W

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BRAF p.V600E immunohistochemistry in challenging samples: about false-positive and false-negative results—reply by Fisher, Kevin E., MD, PhD, Cohen, Cynthia, MD, Palma, John F., PhD, Longshore, John W., PhD

“…[...]we encountered this pitfall numerous times in our study; nonspecific staining secondary to macrophages/histiocytes, and pigmented melanophages in…”
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Comprehensive Molecular Testing Functions Best in a Consolidated Model by Longshore, John W

“…A significant advantage of the core molecular laboratory is often the expansion of testing to multiple shifts, which may lead to a highly efficient delivery of…”
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A Grading System for Invasive Pulmonary Adenocarcinoma: A Proposal From the International Association for the Study of Lung Cancer Pathology Committee by Moreira, Andre L, Ocampo, Paolo S S, Xia, Yuhe, Zhong, Hua, Russell, Prudence A, Minami, Yuko, Cooper, Wendy A, Yoshida, Akihiko, Bubendorf, Lukas, Papotti, Mauro, Pelosi, Giuseppe, Lopez-Rios, Fernando, Kunitoki, Keiko, Ferrari-Light, Dana, Sholl, Lynette M, Beasley, Mary Beth, Borczuk, Alain, Botling, Johan, Brambilla, Elisabeth, Chen, Gang, Chou, Teh-Ying, Chung, Jin-Haeng, Dacic, Sanja, Jain, Deepali, Hirsch, Fred R, Hwang, David, Lantuejoul, Sylvie, Lin, Dongmei, Longshore, John W, Motoi, Noriko, Noguchi, Masayuki, Poleri, Claudia, Rekhtman, Natasha, Tsao, Ming-Sound, Thunnissen, Erik, Travis, William D, Yatabe, Yasushi, Roden, Anja C, Daigneault, Jillian B, Wistuba, Ignacio I, Kerr, Keith M, Pass, Harvey, Nicholson, Andrew G, Mino-Kenudson, Mari

“…A grading system for pulmonary adenocarcinoma has not been established. The International Association for the Study of Lung Cancer pathology panel evaluated a…”
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American College of Medical Genetics Statement on Diagnostic Testing for Uniparental Disomy by Shaffer, Lisa G, Agan, Noelle, Goldberg, James D, Ledbetter, David H, Longshore, John W, Cassidy, Suzanne B

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A retrospective analysis of the clinical performance of human papillomavirus testing using SurePath sample collection by McDermott, James E., MD, Symanowski, James T., PhD, Livasy, Chad A., MD, Greger, Geraldine, CT(ASCP), Longshore, John W., PhD

“…Introduction We present a retrospective analysis of our high-risk human papillomavirus (hr-HPV) test performance using SurePath samples, and we compare these…”
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Abstract 1394: RT-PCR and NGS comparison: detection of known EGFR mutations in non-small-cell lung cancer clinical samples with routine laboratory testing by Palma, John F., Tai, Yu Chuan, Liu, Wei-min, Anderson, Steve, Madan, Anup, Longshore, John W., Rao, Arundhati

“…Abstract Next-generation sequencing (NGS) promises to deliver clinical mutation analysis for multiple actionable biomarkers at once. However, most targeted…”
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Multiplex testing for Factor II and Factor V mutations in thrombophilia: technical verification and clinical validation of the cobas® Factor II and Factor V test by Longshore, John W., DeMartin, Kelli, Yu, Karen, Das, Partha, Zhang, Guili, Rehage, Taraneh Tamaddon, Jethwaney, Deepa, Karwowska, Sylwia

“…Laboratory testing for thrombophilia is complicated but essential for diagnosis. In 2017, the cobas ® Factor II and Factor V Test (cobas F2F5 test) was…”
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Molecular diversity of diazotrophs in oligotrophic tropical seagrass bed communities by Bagwell, Christopher E, La Rocque, Jeannine R, Smith, Garriett W, Polson, Shawn W, Friez, Michael J, Longshore, John W, Lovell, Charles R

“…Denaturing gradient gel electrophoresis (DGGE) was employed to resolve PCR-amplified nifH sequences from vegetated and unvegetated sediments from two…”
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Recovery and phylogenetic analysis of nifH sequences from diazotrophic bacteria associated with dead aboveground biomass of Spartina alterniflora by LOVELL, Charles R, FRIEZ, Michael J, LONGSHORE, John W, BAGWELL, Christopher E

“…DNA was extracted from dry standing dead Spartina alterniflora stalks as well as dry Spartina wrack from the North Inlet (South Carolina) and Sapelo Island…”
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Molecular diversity of diazotrophs in oligotrophic tropical seagrass bed communities by Bagwell, C.E, La Rocque, J.R, Smith, G.W, Polson, S.W, Friez, M.J, Longshore, J.W, Lovell, C.R

“…Denaturing gradient gel electrophoresis (DGGE) was employed to resolve PCR-amplified nifH sequences from vegetated and unvegetated sediments from two…”
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The HOPA Gene Dodecamer Duplication Is Not a Significant Etiological Factor in Autism by Michaelis, Ron C, Copeland-Yates, Susan A, Sossey-Alaoui, Khalid, Skinner, Cindy, Friez, Michael J, Longshore, John W, Simensen, Richard J, Schroer, Richard J, Stevenson, Roger E

“…A study of 202 patients with autism found the incidence of a dodecamer duplication in the HOPA gene was not significantly different between patients and…”
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Accurate detection ofBRAFp.V600E mutations in challenging melanoma specimens requires stringent immunohistochemistry scoring criteria or sensitive molecular assays by Fisher, Kevin E, Cohen, Cynthia, Siddiqui, Momin T, Palma, John F, Lipford, Edward H, Longshore, John W

“…Malignant melanoma patients requireBRAFmutation testing prior to initiating BRAF inhibitor therapy. Molecular testing remains the diagnostic gold standard, but…”
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The evolution of routine PCR testing: insights from the core lab model by Longshore, John W

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