Search Results - "Longo, V"
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Fasting vs dietary restriction in cellular protection and cancer treatment: from model organisms to patients
Published in Oncogene (28-07-2011)“…The dietary recommendation for cancer patients receiving chemotherapy, as described by the American Cancer Society, is to increase calorie and protein intake…”
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Fasting mimicking diet in mice delays cancer growth and reduces immunotherapy-associated cardiovascular and systemic side effects
Published in Nature communications (08-09-2023)“…Immune checkpoint inhibitors cause side effects ranging from autoimmune endocrine disorders to severe cardiotoxicity. Periodic Fasting mimicking diet (FMD)…”
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Metabolic Alterations at the Crossroad of Aging and Oncogenesis
Published in International review of cell and molecular biology (2017)“…Aging represents the major risk factor for cancer. Cancer and aging are characterized by a similar dysregulated metabolism consisting in upregulation of…”
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ITS1 copy number varies among Batrachochytrium dendrobatidis strains: implications for qPCR estimates of infection intensity from field-collected amphibian skin swabs
Published in PloS one (21-03-2013)“…Genomic studies of the amphibian-killing fungus (Batrachochytrium dendrobatidis, [Bd]) identified three highly divergent genetic lineages, only one of which…”
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The impact of a fasting mimicking diet on the metabolic health of a prospective cohort of patients with prostate cancer: a pilot implementation study
Published in Prostate cancer and prostatic diseases (01-06-2023)“…Background This pilot prospective study investigated the effect of a periodic fasting mimicking diet (FMD) on metabolic health factors in patients with…”
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Evolutionary ecology of host competence after a chytrid outbreak in a naive amphibian community
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (31-07-2023)“…Naive multi-host communities include species that may differentially maintain, transmit and amplify novel pathogens; therefore, we expect species to fill…”
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Presence, enzymatic activity, and subcellular localization of paraoxonases 1, 2, and 3 in human lung tissues
Published in Life sciences (1973) (15-12-2022)“…The human paraoxonases family (PONs) includes three calcium-dependent esterases: PON1, PON2, and PON3. The presence of PONs mRNA in human lungs is known,…”
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Inactivation of Ymr1, Sjl2/3 phosphatases promotes stress resistance and longevity in wild type and Ras2G19V yeast
Published in Biomedical Journal (01-04-2024)“…In Saccharomyces cerevisiae, RAt Sarcoma (Ras) activity plays a central role in mediating the effect of glucose in decreasing stress resistance and longevity,…”
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Disentangling host, pathogen, and environmental determinants of a recently emerged wildlife disease: lessons from the first 15 years of amphibian chytridiomycosis research
Published in Ecology and evolution (01-09-2015)“…The amphibian fungal disease chytridiomycosis, which affects species across all continents, recently emerged as one of the greatest threats to biodiversity…”
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Vesicle and Vesicle-Free Extracellular Proteome of Paracoccidioides brasiliensis: Comparative Analysis with Other Pathogenic Fungi
Published in Journal of proteome research (02-03-2012)“…Microorganisms release effector molecules that modulate the host machinery enabling survival, replication, and dissemination of a pathogen. Here we…”
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Seasonal and ontogenetic variation of skin microbial communities and relationships to natural disease dynamics in declining amphibians
Published in Royal Society open science (01-07-2015)“…Recently, microbiologists have focused on characterizing the probiotic role of skin bacteria for amphibians threatened by the fungal disease chytridiomycosis…”
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Lipidomic analysis of extracellular vesicles from the pathogenic phase of Paracoccidioides brasiliensis
Published in PloS one (22-06-2012)“…Fungal extracellular vesicles are able to cross the cell wall and transport molecules that help in nutrient acquisition, cell defense, and modulation of the…”
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Taxane-rechallenge in HER2-positive breast cancer patients who develop an oligo-progression during pertuzumab-trastuzumab maintenance therapy
Published in Annals of oncology (01-10-2017)Get full text
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Disease risk in temperate amphibian populations is higher at closed-canopy sites
Published in PloS one (31-10-2012)“…Habitat loss and chytridiomycosis (a disease caused by the chytrid fungus Batrachochytrium dendrobatidis - Bd) are major drivers of amphibian declines…”
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Direct in situ observation of the electron-driven synthesis of Ag filaments on α-Ag2WO4 crystals
Published in Scientific reports (17-04-2013)“…In this letter, we report, for the first time, the real-time in situ nucleation and growth of Ag filaments on α-Ag 2 WO 4 crystals driven by an accelerated…”
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Comparative Cost-Effectiveness of Two-Tiered Testing Strategies for Serodiagnosis of Lyme Disease with Noncutaneous Manifestations
Published in Journal of Clinical Microbiology (01-12-2013)“…Classifications Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Biological therapy downregulates the heterodimer S100A8/A9 (calprotectin) expression in psoriatic patients
Published in Inflammation research (01-07-2018)“…The pathophysiology of psoriasis is very complex and involves an interplay between immune cells and keratinocytes. The keratinocyte production of calprotectin…”
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Electronic and Structural Properties of the (101̅0) and (112̅0) ZnO Surfaces
Published in The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory (25-09-2008)“…The structural and electronic properties of ZnO (101̅0) and (112̅0) surfaces were investigated by means of density functional theory applied to periodic…”
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Amphibian fungal panzootic causes catastrophic and ongoing loss of biodiversity
Published in Science (American Association for the Advancement of Science) (29-03-2019)“…Anthropogenic trade and development have broken down dispersal barriers, facilitating the spread of diseases that threaten Earth's biodiversity. We present a…”
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