Search Results - "Longo, Kelly P"

Discovery of a potent substance P antagonist: recognition of the key molecular determinant by Desai, Manoj C, Lefkowitz, Sheri L, Thadeio, Peter F, Longo, Kelly P, Snider, R. Michael

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A Potent Nonpeptide Antagonist of the Substance P (NK$_1$) Receptor by Snider, R. Michael, Constantine, Jay W., Lowe, John A., Longo, Kelly P., Lebel, Wesley S., Woody, Heidi A., Drozda, Susan E., Desai, Manoj C., Vinick, Frederic J., Spencer, Robin W., Hess, Hans-Jürgen

“…CP-96,345 [(2S, 3S)-cis-2-(diphenylmethyl)-N-[(2-methoxyphenyl)-methyl]-1-azabicyclo[2.2.2] octan-3-amine] is a potent nonpeptide antagonist of the substance P…”
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The discovery of (2S,3S)-cis-2-(diphenylmethyl)-N-[(2-methoxyphenyl)methyl]-1-azabicyclo[2.2.2]octan-3-amine as a novel, nonpeptide substance P antagonist by Lowe, John A, Drozda, Susan E, Snider, R. Michael, Longo, Kelly P, Zorn, Stevin H, Morrone, Jean, Jackson, Elisa R, McLean, Stafford, Bryce, Dianne K

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Aza-Tricyclic Substance P Antagonists by Lowe, John A, Drozda, Susan E, McLean, Stafford, Bryce, D. K, Crawford, Rosemary T, Snider, R. Michael, Longo, Kelly P, Nagahisa, Atsushi, Tsuchiya, Megumi

“…The synthesis and structure-activity relationships of a series of aza-tricyclic analogs of the quinuclidine substance P (SP) antagonist 1 are described. The SP…”
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Discovery of CP-96,345 and its characterization in disease models involving substance P by Lowe, 3rd, J A, Drozda, S E, Snider, R M, Longo, K P, Zorn, S H, Jackson, E R, Morrone, J, McLean, S, Bryce, D K, Bordner, J

“…Studies with CP-96,345, a potent, selective, orally active, nonpeptide NK1 receptor antagonist, have provided considerable insight into SP pharmacology. Rather…”
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The discovery of (2S,3S)-cis-2-(diphenylmethyl)-N-[(2-methoxyphenyl)methyl]-1-azabicyclo[2.2.2]octan-3-amine as a novel, nonpeptide substance P antagonist. [Erratum to document cited in CA117(5):48289n] by Lowe, John A, Drozda, Susan E, Snider, R. Michael, Longo, Kelly P, Zorn, Stevin H, Morrone, Jean, Jackson, Elisa R, McLean, Stafford, Bryce, Dianne K

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Effect of CP-96,345, a Nonpeptide Substance P Receptor Antagonist, on Salivation in Rats by Snider, R. Michael, Longo, Kelly P., Drozda, Susan E., Lowe, John A., Leeman, Susan E.

“…CP-96,345 {(2S,3S)-cis-2-(diphenylmethyl)-N-[(2-methoxyphenyl)methyl]-1 -azabicyclo[2.2.2]octa N-3-amine} antagonism of substance P-stimulated salivation was…”
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