Search Results - "Longmuir, Kenneth J."
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Use of labeled tomato lectin for imaging vasculature structures
Published in Histochemistry and cell biology (01-02-2015)“…Intravascular injections of fluorescent or biotinylated tomato lectin were tested to study labeling of vascular elements in laboratory mice. Injections of…”
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Cellular organization of normal mouse liver: a histological, quantitative immunocytochemical, and fine structural analysis
Published in Histochemistry and cell biology (01-06-2009)“…The cellular organization of normal mouse liver was studied using light and electron microscopy and quantitative immunocytochemical techniques. The general…”
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Liposomal delivery of doxorubicin to hepatocytes in vivo by targeting heparan sulfate
Published in International journal of pharmaceutics (01-12-2009)“…Previous work demonstrated that liposomes, containing an amino acid sequence that binds to hepatic heparan sulfate glycosaminoglycan, show effective targeting…”
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Effective targeting of liposomes to liver and hepatocytes in vivo by incorporation of a Plasmodium amino acid sequence
Published in Pharmaceutical research (01-04-2006)“…Several species of the protozoan Plasmodium effectively target mammalian liver during the initial phase of host invasion. The purpose of this study was to…”
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Characterization of Kupffer cells in livers of developing mice
Published in Comparative hepatology (12-07-2011)“…Kupffer cells are well known macrophages of the liver, however, the developmental characteristics of Kupffer cells in mice are not well understood. To clarify…”
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Interactive Computer-Assisted Instruction in Acid-Base Physiology for Mobile Computer Platforms
Published in Advances in physiology education (01-03-2014)“…In this project, the traditional lecture hall presentation of acid-base physiology in the first-year medical school curriculum was replaced by interactive,…”
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A practical guide to the staggered herringbone mixer
Published in Lab on a chip (01-01-2008)“…An analytical model of mixing in the staggered herringbone mixer (SHM) was derived to estimate mixing parameters and provide practical expressions to guide…”
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Development, differentiation, and vascular components of subcutaneous and intrahepatic Hepa129 tumors in a mouse model of hepatocellular carcinoma
Published in Histology and histopathology (01-04-2016)“…Tumor models in mice offer opportunities for understanding tumor formation and development of therapeutic treatments for hepatocellular carcinoma. In this…”
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Liposomes incorporating a Plasmodium amino acid sequence target heparan sulfate binding sites in liver
Published in Journal of pharmaceutical sciences (01-08-2008)“…Previous studies demonstrated that intravenously administered liposomes, incorporating a peptide from the Plasmodium circumsporozoite protein, accumulate…”
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Using electroporation and lipid-mediated transfection of GFP-expressing plasmids to label embryonic avian cells for vital confocal and two-photon microscopy
Published in Differentiation (London) (01-06-2002)“…Fluorescent proteins have emerged as an ideal fluorescent marker for studying cell morphologies in vital systems. These proteins were first applied in whole…”
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Binding patterns of peptide-containing liposomes in liver and spleen of developing mice: comparison with heparan sulfate immunoreactivity
Published in Journal of drug targeting (01-08-2011)“…Background: Liposomes incorporating peptide from the Plasmodium circumsporozoite protein (CSP) accumulate rapidly and selectively in adult mouse liver…”
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Liposomal polyethyleneglycol and polyethyleneglycol-peptide combinations for active targeting to liver in vivo
Published in Drug delivery (01-05-2008)“…This report describes the development and evaluation of a range of polyethyleneglycol and polyethyleneglycol-peptide liposome formulations that effectively…”
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Compaction of DNA in an anionic micelle environment followed by assembly into phosphatidylcholine liposomes
Published in Nucleic acids research (01-08-2000)“…A difficult problem concerning the interaction of DNA with amphiphiles of opposite charge above their critical micelle concentration is the propensity for…”
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Optimization of a Peptide/Non-cationic Lipid Gene Delivery System for Effective Microinjection into Chicken Embryo in Vivo
Published in Molecular therapy (01-07-2001)“…Here we report the characterization and optimization of a peptide/non-cationic lipid gene delivery system that successfully produces high levels of gene…”
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Mechanism of human lymphotoxin and tumor necrosis factor induced destruction of cells in vitro: phospholipase activation and deacylation of specific-membrane phospholipids
Published in Journal of cellular physiology (01-03-1990)“…The role of phospholipase (PLase) activation and lipid metabolism in lymphotoxin (LT)- and tumor necrosis factor (TNF)-mediated destruction of murine L929…”
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Purification of long-chain, saturated, free fatty acids
Published in Journal of chromatography (1988)Get more information
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Nuclear magnetic resonance studies of lipid-protein interactions. A model of the dynamics and energetics of phosphatidylcholine bilayers that contain cytochrome c oxidase
Published in Biochemistry (Easton) (01-12-1977)“…Reconstituted membrane systems of synthetic phosphatidylcholines and the integral membrane enzyme cytochrome c oxidase were prepared in order to conduct…”
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Development of an effective gene delivery system: a study of complexes composed of a peptide-based amphiphilic DNA compaction agent and phospholipid
Published in Nucleic acids research (01-09-2001)“…We recently described a basic technology to efficiently combine compacted DNA with phospholipids and hydrophobic peptides, to produce homogenous complexes that…”
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Cytokine- and calcium ionophore A23187-mediated arachidonic acid metabolism in neutrophils
Published in Cytokine (Philadelphia, Pa.) (01-07-1990)“…Arachidonic acid (AA) metabolism is implicated as an intracellular and/or intercellular second messenger system for the transmission of cytokine-initiated…”
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