Search Results - "Longini, IM"

Containing Pandemic Influenza with Antiviral Agents by Longini, Ira M., Halloran, M. Elizabeth, Nizam, Azhar, Yang, Yang

“…For the first wave of pandemic influenza or a bioterrorist influenza attack, antiviral agents would be one of the few options to contain the epidemic in the…”
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Containing Bioterrorist Smallpox by Halloran, M. Elizabeth, Longini, Ira M., Nizam, Azhar, Yang Yang

“…The need for a planned response to a deliberate introduction of smallpox has recently become urgent. We constructed a stochastic simulator of the spread of…”
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A 4-Year Study of the Epidemiology of Vibrio cholerae in Four Rural Areas of Bangladesh by Sack, R. Bradley, Siddique, A. Kasem, Longini, Ira M., Nizam, Azhar, Yunus, Md, Islam, M. Sirajul, Morris, Jr, J. Glenn, Ali, Afsar, Huq, Anwar, Nair, G. Balakrish, Qadri, Firdausi, Faruque, Shah M., Sack, David A., Colwell, Rita R.

“…How Vibrio cholerae spreads around the world and what determines its seasonal peaks in endemic areas are not known. These features of cholera have been…”
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Epidemic and Endemic Cholera Trends over a 33-Year Period in Bangladesh by Longini, Ira M., Yunus, Mohammed, Zaman, K., Siddique, A. K., Sack, R. Bradley, Nizam, Azhar

“…Despite nearly 200 years of study, the mechanisms contributing to the maintenance of endemic cholera and the causes of periodic epidemics remain poorly…”
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The critical vaccination fraction for heterogeneous epidemic models by Hill, Andrew N., Longini, Ira M.

“…Given a population with m heterogeneous subgroups, a method is developed for determining minimal vaccine allocations to prevent an epidemic by setting the…”
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Subtype-specific Transmission Probabilities for Human Immunodeficiency Virus Type 1 among Injecting Drug Users in Bangkok, Thailand by Hudgens, Michael G., Longini, Ira M., Vanichseni, Suphak, Hu, Dale J., Kitayaporn, Dwip, Mock, Philip A., Halloran, M. Elizabeth, Satten, Glen A., Choopanya, Kachit, Mastro, Timothy D.

“…The Bangkok (Thailand) Metropolitan Administration cohort of injecting drug users (IDUs) consisted of 1,209 IDUs initially seronegative for human…”
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Estimation of the efficacy of live, attenuated influenza vaccine from a two-year, multi-center vaccine trial: implications for influenza epidemic control by Longini, Ira M, Halloran, M.Elizabeth, Nizam, Azhar, Wolff, Mark, Mendelman, Paul M, Fast, Patricia E, Belshe, Robert B

“…The authors provide an analysis of data from a two-year (1996–1998), multicenter (ten US cities), double-blinded, placebo-controlled influenza vaccine trial in…”
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Direct and indirect effects in vaccine efficacy and effectiveness by Halloran, M E, Haber, M, Longini, Jr, I M, Struchiner, C J

“…In 1915, Greenwood and Yule noted that for valid vaccine efficacy studies, exposure to infection in the vaccinated and the unvaccinated must be equal (Proc R…”
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COVID-19 vaccine trials should seek worthwhile efficacy by Krause, Philip, Fleming, Thomas R, Longini, Ira, Henao-Restrepo, Ana Maria, Peto, Richard, Dean, NE, Halloran, ME, Huang, Y, Fleming, TR, Gilbert, PB, DeGruttola, V, Janes, HE, Krause, PR, Longini, IM, Nason, MC, Peto, R, Smith, PG, Riveros, AX, Gsell, PS, Henao-Restrepo, AM

“…[...]the initial trials comparing COVID-19 vaccines versus placebo should seek reliable evidence not only of some efficacy but of worthwhile efficacy…”
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Estimation of Vaccine Efficacy in the Presence of Waning: Application to Cholera Vaccines by Durham, L. Kathryn, Longini, Ira M., Halloran, M. Elizabeth, Clemens, John D., Azhar, Nizam, Rao, Malla

“…The authors present a nonparametric method for estimating vaccine efficacy as a smooth function of time from vaccine trials. Use of the method requires a…”
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Mitigation Strategies for Pandemic Influenza in the United States by Germann, Timothy C., Kadau, Kai, Longini, Ira M., Macken, Catherine A.

“…Recent human deaths due to infection by highly pathogenic (H5N1) avian influenza A virus have raised the specter of a devastating pandemic like that of…”
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Augmented HIV vaccine trial design for estimating reduction in infectiousness and protective efficacy by Datta, Susmita, Halloran, M. Elizabeth, Longini Jr, Ira M.

“…It is important to design HIV vaccine trials to estimate the efficacy of a vaccine in reducing infectiousness in addition to the protective efficacy. Currently…”
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Containing Pandemic Influenza at the Source by Longini, Ira M, Nizam, Azhar, Xu, Shufu, Ungchusak, Kumnuan, Hanshaoworakul, Wanna, Cummings, Derek A. T, Halloran, M. Elizabeth

“…Highly pathogenic avian influenza A (subtype H5N1) is threatening to cause a human pandemic of potentially devastating proportions. We used a stochastic…”
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Determinants and predictors of dengue infection in Mexico by Koopman, J S, Prevots, D R, Vaca Marin, M A, Gomez Dantes, H, Zarate Aquino, M L, Longini, Jr, I M, Sepulveda Amor, J

“…A national serosurvey was conducted in Mexico from March to October 1986 to identify predictors of dengue transmission and target areas at high risk of severe…”
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A Markov model for measuring vaccine efficacy for both susceptibility to infection and reduction in infectiousness for prophylactic HIV vaccines by Longini Jr, Ira M., Hudgens, Michael G., Halloran, M. Elizabeth, Sagatelian, Karen

“…We use a discrete‐time non‐homogeneous Markov chain to model data from augmented human immunodeficiency virus (HIV) vaccine trials. For this design, the study…”
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No HIV stage is dominant in driving the HIV epidemic in sub-Saharan Africa by ABU-RADDAD, Laith J, LONGINI, Ira M

“…To estimate the role of each of the HIV progression stages in fueling HIV transmission in sub-Saharan Africa by using the recent measurements of HIV…”
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Effect of routine use of therapy in slowing the clinical course of human immunodeficiency virus (HIV) infection in a population-based cohort by Longini, Jr, I M, Clark, W S, Karon, J M

“…Clinical trials have shown that the prophylactic use of zidovudine and aerosolized pentamidine (or other antibiotics used as prophylaxis against Pneumocystis…”
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Statistical inference for infectious diseases. Risk-specific household and community transmission parameters by Longini, Jr, I M, Koopman, J S, Haber, M, Cotsonis, G A

“…A statistical model is presented for the analysis of infectious disease data from family studies in the community. The model partitions the sources of…”
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Strategy for Distribution of Influenza Vaccine to High-Risk Groups and Children by Longini, Ira M., Halloran, M. Elizabeth

“…Despite evidence that vaccinating schoolchildren against influenza is effective in limiting community-level transmission, the United States has had a…”
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Modelling the female-to-male per-act HIV transmission probability in an emerging epidemic in Asia by Satten, G A, Mastro, T D, Longini, Jr, I M

“…The per-sexual-act probability of transmission of the human immunodeficiency virus type 1 (HIV) from an infected person to a susceptible sex partner can be…”
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