Search Results - "Longhurst, Colin A"

Drosophila Nociceptive Sensitization Requires BMP Signaling via the Canonical SMAD Pathway by Follansbee, Taylor L, Gjelsvik, Kayla J, Brann, Courtney L, McParland, Aidan L, Longhurst, Colin A, Galko, Michael J, Ganter, Geoffrey K

“…Nociceptive sensitization is a common feature in chronic pain, but its basic cellular mechanisms are only partially understood. The present study used the…”
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Complex confounder-corrected R2 mapping for liver iron quantification with MRI by Hernando, Diego, Cook, Rachel J., Qazi, Naila, Longhurst, Colin A., Diamond, Carol A., Reeder, Scott B.

“…Objectives MRI-based R2* mapping may enable reliable and rapid quantification of liver iron concentration (LIC). However, the performance and reproducibility…”
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MET Inhibitor Capmatinib Radiosensitizes MET Exon 14-Mutated and MET-Amplified Non-Small Cell Lung Cancer by Ramesh, Shrey, Cifci, Ahmet, Javeri, Saahil, Minne, Rachel L., Longhurst, Colin A., Nickel, Kwangok P., Kimple, Randall J., Baschnagel, Andrew M.

“…The objective of this study was to investigate the effects of inhibiting the MET receptor with capmatinib, a potent and clinically relevant ATP-competitive…”
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Mammary Tumors Growing in the Absence of Growth Hormone Are More Sensitive to Doxorubicin Than Wild-Type Tumors by Lantvit, Daniel D, Unterberger, Christopher J, Lazar, Michelle, Arneson, Paige D, Longhurst, Colin A, Swanson, Steven M, Marker, Paul C

“…Previously, we reported that N-methyl-N-nitrosourea (MNU)-induced mammary tumors could be established in mutant spontaneous dwarf rats (SDRs), which lack…”
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ATR Inhibitor M6620 (VX-970) Enhances the Effect of Radiation in Non-Small Cell Lung Cancer Brain Metastasis Patient-Derived Xenografts by Baschnagel, Andrew M, Elnaggar, Jacob H, VanBeek, Haley J, Kromke, Ashley C, Skiba, Justin H, Kaushik, Saakshi, Abel, Lindsey, Clark, Paul A, Longhurst, Colin A, Nickel, Kwangok P, Leal, Ticiana A, Zhao, Shuang G, Kimple, Randall J

“…M6620, a selective ATP-competitive inhibitor of the ATM and RAD3-related (ATR) kinase, is currently under investigation with radiation in patients with…”
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AXL Mediates Cetuximab and Radiation Resistance Through Tyrosine 821 and the c-ABL Kinase Pathway in Head and Neck Cancer by McDaniel, Nellie K, Iida, Mari, Nickel, Kwangok P, Longhurst, Colin A, Fischbach, Samantha R, Rodems, Tamara S, Kranjac, Carlene A, Bo, Amber Y, Luo, Qianyun, Gallagher, Meghan M, Welke, Noah B, Mitchell, Kaitlyn R, Schulz, Alison E, Eckers, Jaimee C, Hu, Rong, Salgia, Ravi, Hong, Seungpyo, Bruce, Justine Y, Kimple, Randall J, Wheeler, Deric L

“…Radiation and cetuximab are therapeutics used in management of head and neck squamous cell carcinoma (HNSCC). Despite clinical success with these modalities,…”
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FGFR Inhibition Enhances Sensitivity to Radiation in Non-Small Cell Lung Cancer by SenthilKumar, Gopika, Fisher, Michael M, Skiba, Justin H, Miller, Margot C, Brennan, Sean R, Kaushik, Saakshi, Bradley, Samantha T, Longhurst, Colin A, Buehler, Darya, Nickel, Kwangok P, Iyer, Gopal, Kimple, Randall J, Baschnagel, Andrew M

“…FGFRs are commonly altered in non-small cell lung cancer (NSCLC). FGFRs activate multiple pathways including RAS/RAF/MAPK, PI3K/AKT, and STAT, which may play a…”
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Skeletal Muscle Adiposity and Lung Function Trajectory in the Severe Asthma Research Program by Tattersall, Matthew C, Lee, Kristine E, Tsuchiya, Nanae, Osman, Fauzia, Korcarz, Claudia E, Hansen, Kristin M, Peters, Michael C, Fahy, John V, Longhurst, Colin A, Dunican, Eleanor, Wentzel, Sally E, Leader, Joseph K, Israel, Elliot, Levy, Bruce D, Castro, Mario, Erzurum, Serpil C, Lempel, Jason, Moore, Wendy C, Bleecker, Eugene R, Phillips, Brenda R, Mauger, David T, Hoffman, Eric A, Fain, Sean B, Reeder, Scott B, Sorkness, Ron L, Jarjour, Nizar N, Denlinger, Loren C, Schiebler, Mark L

“…Extrapulmonary manifestations of asthma, including fatty infiltration in tissues, may reflect systemic inflammation and influence lung function and disease…”
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From Bench to Bedside: A Team's Approach to Multidisciplinary Strategies to Combat Therapeutic Resistance in Head and Neck Squamous Cell Carcinoma by Crossman, Bridget E, Harmon, Regan L, Kostecki, Kourtney L, McDaniel, Nellie K, Iida, Mari, Corday, Luke W, Glitchev, Christine E, Crow, Madisen T, Harris, Madelyn A, Lin, Candie Y, Adams, Jillian M, Longhurst, Colin A, Nickel, Kwangok P, Ong, Irene M, Alexandridis, Roxana A, Yu, Menggang, Yang, David T, Hu, Rong, Morris, Zachary S, Hartig, Gregory K, Glazer, Tiffany A, Ramisetty, Sravani, Kulkarni, Prakash, Salgia, Ravi, Kimple, Randall J, Bruce, Justine Y, Harari, Paul M, Wheeler, Deric L

“…Head and neck squamous cell carcinoma (HNSCC) is diagnosed in more than 71,000 patients each year in the United States, with nearly 16,000 associated deaths…”
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COMPARING COGNITIVE BATTERIES: UNIFORM DATA SET 2 (UDS-2) AND UNIFORM DATA SET 3 (UDS-3) IN NON-HISPANIC WHITE PARTICIPANTS AND THOSE FROM UNDERREPRESENTED GROUPS ENROLLED IN THE WISCONSIN ALZHEIMER'S DISEASE RESEARCH CENTER'S CLINICAL CORE by Holt, Naomi C., Wahoske, Michelle L., Longhurst, Colin A., Wyman, Mary F., Blazel, Hanna, Chappell, Richard J., Carlsson, Cynthia M., Johnson, Sterling C., Asthana, Sanjay, Gleason, Carey E.

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