Search Results - "Longhi, Maria P"
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Myeloid apolipoprotein E controls dendritic cell antigen presentation and T cell activation
Published in Nature communications (06-08-2018)“…Cholesterol homeostasis has a pivotal function in regulating immune cells. Here we show that apolipoprotein E (apoE) deficiency leads to the accumulation of…”
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Induction of innate and adaptive immunity by delivery of poly dA:dT to dendritic cells
Published in Nature chemical biology (01-04-2013)“…A conjugate generated by expressed protein ligation between an antibody targeting dendritic cells (DCs) and an immune-stimulating double-stranded DNA reveals…”
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Obesity-Induced Metabolic Stress Leads to Biased Effector Memory CD4+ T Cell Differentiation via PI3K p110δ-Akt-Mediated Signals
Published in Cell metabolism (07-03-2017)“…Low-grade systemic inflammation associated to obesity leads to cardiovascular complications, caused partly by infiltration of adipose and vascular tissue by…”
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Metabolic and Innate Immune Cues Merge into a Specific Inflammatory Response via the UPR
Published in Cell (16-05-2019)“…Innate immune responses are intricately linked with intracellular metabolism of myeloid cells. Toll-like receptor (TLR) stimulation shifts intracellular…”
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Metabolic and Innate Immune Cues Merge into a Specific Inflammatory Response via the UPR
Published in Cell (27-06-2019)Get full text
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Metabolic and innate immune cues merge into a specific inflammatory response via unfolded proteinresponse (UPR)
Published in Cell (16-05-2019)“…Innate immune responses are intricately linked with intracellular metabolism of myeloid cells. Toll-likereceptor (TLR) stimulation shifts intracellular…”
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Journal Article