Search Results - "Long, Yongkang"

A deep learning framework to predict binding preference of RNA constituents on protein surface by Lam, Jordy Homing, Li, Yu, Zhu, Lizhe, Umarov, Ramzan, Jiang, Hanlun, Héliou, Amélie, Sheong, Fu Kit, Liu, Tianyun, Long, Yongkang, Li, Yunfei, Fang, Liang, Altman, Russ B., Chen, Wei, Huang, Xuhui, Gao, Xin

“…Protein-RNA interaction plays important roles in post-transcriptional regulation. However, the task of predicting these interactions given a protein structure…”
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Integrative multi-omics analysis of a colon cancer cell line with heterogeneous Wnt activity revealed RUNX2 as an epigenetic regulator of EMT by Yi, Hongyang, Li, Guipeng, Long, Yongkang, Liang, Weizheng, Cui, Huanhuan, Zhang, Bin, Tan, Ying, Li, Yunfei, Shen, Luochen, Deng, Daqi, Tang, Yisen, Mao, Chenyu, Tian, Shuye, Cai, Yunting, Zhu, Qionghua, Hu, Yuhui, Chen, Wei, Fang, Liang

“…Epithelial–mesenchymal transition (EMT) program, which facilitates tumor metastasis, stemness and therapy resistance, is a reversible biological process that…”
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DeeReCT-APA: Prediction of Alternative Polyadenylation Site Usage Through Deep Learning by Li, Zhongxiao, Li, Yisheng, Zhang, Bin, Li, Yu, Long, Yongkang, Zhou, Juexiao, Zou, Xudong, Zhang, Min, Hu, Yuhui, Chen, Wei, Gao, Xin

“…Alternative polyadenylation (APA) is a crucial step in post-transcriptional regulation. Previous bioinformatic studies have mainly focused on the recognition…”
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Annotating TSSs in Multiple Cell Types Based on DNA Sequence and RNA-seq Data via DeeReCT-TSS by Zhou, Juexiao, Zhang, Bin, Li, Haoyang, Zhou, Longxi, Li, Zhongxiao, Long, Yongkang, Han, Wenkai, Wang, Mengran, Cui, Huanhuan, Li, Jingjing, Chen, Wei, Gao, Xin

“…The accurate annotation of transcription start sites (TSSs) and their usage are critical for the mechanistic understanding of gene regulation in different…”
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Accurate transcriptome-wide identification and quantification of alternative polyadenylation from RNA-seq data with APAIQ by Long, Yongkang, Zhang, Bin, Tian, Shuye, Chan, Jia Jia, Zhou, Juexiao, Li, Zhongxiao, Li, Yisheng, An, Zheng, Liao, Xingyu, Wang, Yu, Sun, Shiwei, Xu, Ying, Tay, Yvonne, Chen, Wei, Gao, Xin

“…Alternative polyadenylation (APA) enables a gene to generate multiple transcripts with different 3' ends, which is dynamic across different cell types or…”
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Recessive, Deleterious Variants in SMG8 Expand the Role of Nonsense-Mediated Decay in Developmental Disorders in Humans by Alzahrani, Fatema, Kuwahara, Hiroyuki, Long, Yongkang, Al-Owain, Mohammed, Tohary, Mohamed, AlSayed, Moeenaldeen, Mahnashi, Mohammed, Fathi, Lana, Alnemer, Maha, Al-Hamed, Mohamed H., Lemire, Gabrielle, Boycott, Kym M., Hashem, Mais, Han, Wenkai, Al-Maawali, Almundher, Al Mahrizi, Feisal, Al-Thihli, Khalid, Gao, Xin, Alkuraya, Fowzan S.

“…We have previously described a heart-, eye-, and brain-malformation syndrome caused by homozygous loss-of-function variants in SMG9, which encodes a critical…”
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FAM46B is a prokaryotic-like cytoplasmic poly(A) polymerase essential in human embryonic stem cells by Hu, Jia-Li, Liang, He, Zhang, Hong, Yang, Ming-Zhu, Sun, Wei, Zhang, Peng, Luo, Li, Feng, Jian-Xiong, Bai, Huajun, Liu, Fang, Zhang, Tianpeng, Yang, Jin-Yu, Gao, Qingsong, Long, Yongkang, Ma, Xiao-Yan, Chen, Yang, Zhong, Qian, Yu, Bing, Liao, Shuang, Wang, Yongbo, Zhao, Yong, Zeng, Mu-Sheng, Cao, Nan, Wang, Jichang, Chen, Wei, Yang, Huang-Tian, Gao, Song

“…Family with sequence similarity (FAM46) proteins are newly identified metazoan-specific poly(A) polymerases (PAPs). Although predicted as Gld-2-like eukaryotic…”
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A deep learning framework to predict binding preference of RNA constituents on protein surface by Lam, Jordy Homing, Li, Yu, Zhu, Lizhe, Umarov, Ramzan, Jiang, Hanlun, Héliou, Amélie, Sheong, Fu Kit, Liu, Tianyun, Long, Yongkang, Li, Yunfei, Fang, Liang, Altman, Russ, Chen, Wei, Huang, Xuhui, Gao, Xin

“…Abstract Protein-RNA interaction plays important roles in post-transcriptional regulation. However, the task of predicting these interactions given a protein…”
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