Search Results - "Long, T"

Enhancement of trans-cleavage activity of Cas12a with engineered crRNA enables amplified nucleic acid detection by Nguyen, Long T., Smith, Brianna M., Jain, Piyush K.

“…The CRISPR-Cas12a RNA-guided complexes have tremendous potential for nucleic acid detection but are limited to the picomolar detection limit without an…”
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Studying the Safety Impact of Autonomous Vehicles Using Simulation-Based Surrogate Safety Measures by Vu, Hai L., Truong, Long T., Tian, Qingyun, Morando, Mark Mario

“…Autonomous vehicle (AV) technology has advanced rapidly in recent years with some automated features already available in vehicles on the market. AVs are…”
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Individual and combined effects of working conditions, physical and mental conditions, and risky driving behaviors on taxi crashes in China by Peng, Zhipeng, Wang, Yonggang, Truong, Long T.

“…•A hypothesized four-level structure for triggering taxi crashes was validated.•Individual and combined effects of various factors were identified.•Sleep…”
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Macroscopic road safety impacts of public transport: A case study of Melbourne, Australia by Truong, Long T., Currie, Graham

“…•Road safety effects of commuting by public transport have been analysed.•Random effect negative binomial and conditional autoregressive models were…”
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Host DNases prevent vascular occlusion by neutrophil extracellular traps by Jiménez-Alcázar, Miguel, Rangaswamy, Chandini, Panda, Rachita, Bitterling, Josephine, Simsek, Yashin J., Long, Andy T., Bilyy, Rostyslav, Krenn, Veit, Renné, Christoph, Renné, Thomas, Kluge, Stefan, Panzer, Ulf, Mizuta, Ryushin, Mannherz, Hans Georg, Kitamura, Daisuke, Herrmann, Martin, Napirei, Markus, Fuchs, Tobias A.

“…Platelet and fibrin clots occlude blood vessels in hemostasis and thrombosis. Here we report a noncanonical mechanism for vascular occlusion based on…”
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Opportunities and Challenges for the Sustainability of Lakes and Reservoirs in Relation to the Sustainable Development Goals (SDGs) by Ho, Long T., Goethals, Peter L. M.

“…Emerging global threats, such as biological invasions, climate change, land use intensification, and water depletion, endanger the sustainable future of lakes…”
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Design of waste stabilization pond systems: A review by Ho, Long T., Van Echelpoel, Wout, Goethals, Peter L.M.

“…A better design instruction for waste stabilization ponds is needed due to their growing application for wastewater purification, increasingly strict…”
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China's wind industry: Leading in deployment, lagging in innovation by Lam, Long T., Branstetter, Lee, Azevedo, Inês M.L.

“…China's massive carbon emissions and air pollution concerns have led its government to embrace clean energy innovation as a means of transitioning to a more…”
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Selective Bypass of a Lagging Strand Roadblock by the Eukaryotic Replicative DNA Helicase by Fu, Yu V., Yardimci, Hasan, Long, David T., Guainazzi, Angelo, Bermudez, Vladimir P., Hurwitz, Jerard, van Oijen, Antoine, Schärer, Orlando D., Walter, Johannes C.

“…The eukaryotic replicative DNA helicase, CMG, unwinds DNA by an unknown mechanism. In some models, CMG encircles and translocates along one strand of DNA while…”
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The plasma contact system, a protease cascade at the nexus of inflammation, coagulation and immunity by Weidmann, Henri, Heikaus, Laura, Long, Andy T., Naudin, Clément, Schlüter, Hartmut, Renné, Thomas

“…The contact system is a potent procoagulant and proinflammatory plasma protease cascade that is initiated by binding (“contact”)-induced, auto-activation of…”
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Extraction of high quality and high yield RNA from frozen EDTA blood by Nguyen, Long T., Pollock, Carol A., Saad, Sonia

“…Peripheral blood RNA profiling, which can reveal systemic changes in gene expression and immune responses to disease onset and progression, is a powerful tool…”
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Factor XII as a Therapeutic Target in Thromboembolic and Inflammatory Diseases by Nickel, Katrin F, Long, Andy T, Fuchs, Tobias A, Butler, Lynn M, Renné, Thomas

“…Coagulation factor XII (FXII, Hageman factor) is a plasma protease that in its active form (FXIIa) initiates the procoagulant and proinflammatory contact…”
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SIRT1 overexpression attenuates offspring metabolic and liver disorders as a result of maternal high‐fat feeding by Nguyen, Long T., Chen, Hui, Zaky, Amgad, Pollock, Carol, Saad, Sonia

“…Key points Maternal high‐fat diet (MHF) consumption led to metabolic and liver disorders in male offspring, which are associated with reduced sirtuin (SIRT)1…”
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Programmable RNA detection with CRISPR-Cas12a by Rananaware, Santosh R., Vesco, Emma K., Shoemaker, Grace M., Anekar, Swapnil S., Sandoval, Luke Samuel W., Meister, Katelyn S., Macaluso, Nicolas C., Nguyen, Long T., Jain, Piyush K.

“…Cas12a, a CRISPR-associated protein complex, has an inherent ability to cleave DNA substrates and is utilized in diagnostic tools to identify DNA molecules. We…”
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BRCA1 Promotes Unloading of the CMG Helicase from a Stalled DNA Replication Fork by Long, David T., Joukov, Vladimir, Budzowska, Magda, Walter, Johannes C.

“…The tumor suppressor protein BRCA1 promotes homologous recombination (HR), a high-fidelity mechanism to repair DNA double-strand breaks (DSBs) that arise…”
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Retrieving people: Identifying potential answerers in Community Question‐Answering by Le, Long T., Shah, Chirag

“…Community Question‐Answering (CQA) sites have become popular venues where people can ask questions, seek information, or share knowledge with a user community…”
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Advances in Direct Metal-Catalyzed Functionalization of Azobenzenes by Nguyen, T. H. Long, Gigant, Nicolas, Joseph, Delphine

“…Azobenzenes are a unique class of compounds that originally aroused interest because of their exceptional photochromic properties. Selective reactions allowing…”
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Pore pressure and explosive spalling in concrete by Phan, Long T.

“…Results of an experimental study, which measured thermally-induced pore pressure and corresponding concrete temperatures in high-strength concrete (HSC) and…”
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Bi-directional analysis between fatty liver and cardiovascular disease risk factors by Ma, Jiantao, Hwang, Shih-Jen, Pedley, Alison, Massaro, Joseph M, Hoffmann, Udo, Chung, Raymond T, Benjamin, Emelia J, Levy, Daniel, Fox, Caroline S, Long, Michelle T

“…Graphical abstract…”
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Mechanism of RAD51-Dependent DNA Interstrand Cross-Link Repair by Long, David T., Räschle, Markus, Joukov, Vladimir, Walter, Johannes C.

“…DNA interstrand cross-links (ICLs) are toxic DNA lesions whose repair in S phase of eukaryotic cells is incompletely understood. In Xenopus egg extracts, ICL…”
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