Search Results - "Long, Patrick M."

Tauopathy with paired helical filaments in an aged chimpanzee by Rosen, Rebecca F., Farberg, Aaron S., Gearing, Marla, Dooyema, Jeromy, M. Long, Patrick, Anderson, Daniel C., Davis-Turak, Jeremy, Coppola, Giovanni, Geschwind, Daniel H., Paré, Jean-Francois, Duong, Timothy Q., Hopkins, William D., Preuss, Todd M., Walker, Lary C.

“…An enigmatic feature of age‐related neurodegenerative diseases is that they seldom, if ever, are fully manifested in nonhuman species under natural conditions…”
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Acetate Supplementation as a Means of Inducing Glioblastoma Stem-Like Cell Growth Arrest by Long, Patrick M., Tighe, Scott W., Driscoll, Heather E., Fortner, Karen A., Viapiano, Mariano S., Jaworski, Diane M.

“…Glioblastoma (GBM), the most common primary adult malignant brain tumor, is associated with a poor prognosis due, in part, to tumor recurrence mediated by…”
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Acetate supplementation induces growth arrest of NG2/PDGFRα-positive oligodendroglioma-derived tumor-initiating cells by Long, Patrick M, Tighe, Scott W, Driscoll, Heather E, Moffett, John R, Namboodiri, Aryan M A, Viapiano, Mariano S, Lawler, Sean E, Jaworski, Diane M

“…Cancer is associated with globally hypoacetylated chromatin and considerable attention has recently been focused on epigenetic therapies. N-acetyl-L-aspartate…”
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N-Acetylaspartate (NAA) and N-Acetylaspartylglutamate (NAAG) Promote Growth and Inhibit Differentiation of Glioma Stem-like Cells by Long, Patrick M., Moffett, John R., Namboodiri, Aryan M.A., Viapiano, Mariano S., Lawler, Sean E., Jaworski, Diane M.

“…Metabolic reprogramming is a pathological feature of cancer and a driver of tumor cell transformation. N-Acetylaspartate (NAA) is one of the most abundant…”
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Triacetin‐based acetate supplementation as a chemotherapeutic adjuvant therapy in glioma by Tsen, Andrew R., Long, Patrick M., Driscoll, Heather E., Davies, Matthew T., Teasdale, Benjamin A., Penar, Paul L., Pendlebury, William W., Spees, Jeffrey L., Lawler, Sean E., Viapiano, Mariano S., Jaworski, Diane M.

“…Cancer is associated with epigenetic (i.e., histone hypoacetylation) and metabolic (i.e., aerobic glycolysis) alterations. Levels of N‐acetyl‐l‐aspartate…”
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Differential aminoacylase expression in neuroblastoma by Long, Patrick M., Stradecki, Holly M., Minturn, Jane E., Wesley, Umadevi V., Jaworski, Diane M.

“…Neuroblastoma, a cancer of the sympathetic nervous system, is the most common extracranial solid tumor in children. MYCN amplification and increased BDNF/TrkB…”
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Abstract 3663: Characterization of aspartoacylase in oligodendroglioma by Long, Patrick M.

“…Abstract Aspartoacylase (ASPA, ACY2) is an oligodendrocyte-derived amino acid deacetylase (aminoacylase) responsible for supplying acetate for myelin lipid…”
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Acetate Supplementation as a Means of Inducing Glioblastoma Stem-Like Cell Growth Arrest: ACETATE INDUCEs GLIOMA CELL GROWTH ARREST by Long, Patrick M., Tighe, Scott W., Driscoll, Heather E., Fortner, Karen A., Viapiano, Mariano S., Jaworski, Diane M.

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N-Acetylaspartate (NAA) and N-acetylaspartylglutamate (NAAG) promote growth and inhibit differentiation of glioma stem-like cells by Long, Patrick M., Moffett, John R., Namboodiri, Aryan M.A., Viapiano, Mariano S., Lawler, Sean E., Jaworski, Diane M.

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Abstract 3481: Dietary acetate supplementation as a means of inducing glioma stem cell growth arrest by Long, Patrick M., Tsen, Andrew, Moffett, John R., Namboodiri, Aryan M. A., Viapiano, Mariano S., Jaworski, Diane M.

“…Abstract Glioma, the most common primary brain tumor of the adult central nervous system, is associated with a poor prognosis due, in part, to the presence of…”
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Suppressive effects of soluble histocompatibility antigens on the in vitro generation of cytotoxic T cells to D-end alloantigens by Long, P M, Sommer, C V, Kong, Y M

“…Murine histocompatibility antigens were solubilized from the spleens and lungs of C57BL/6 (H-2b) animals with hypertonic salt (3 M KC1). Aggregate-free soluble…”
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