Search Results - "Long, Joseph D"
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Site-Specific Gene Editing of Human Hematopoietic Stem Cells for X-Linked Hyper-IgM Syndrome
Published in Cell reports (Cambridge) (29-05-2018)“…X-linked hyper-immunoglobulin M (hyper-IgM) syndrome (XHIM) is a primary immunodeficiency due to mutations in CD40 ligand that affect immunoglobulin…”
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2
Improved Companion Mass Limits for Sirius A with Thermal Infrared Coronagraphy Using a Vector-apodizing Phase Plate and Time-domain Starlight-subtraction Techniques
Published in The Astronomical journal (01-05-2023)“…Abstract We use observations with the infrared-optimized Magellan Adaptive Optics (MagAO) system and Clio camera in 3.9 μ m light to place stringent mass…”
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3
MagAO-X and HST High-contrast Imaging of the AS209 Disk at Hα
Published in The Astronomical journal (01-10-2023)“…Abstract The detection of emission lines associated with accretion processes is a direct method for studying how and where gas giant planets form, how young…”
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4
A comparison of DNA repair pathways to achieve a site-specific gene modification of the Bruton's tyrosine kinase gene
Published in Molecular therapy. Nucleic acids (08-03-2022)“…Gene editing utilizing homology-directed repair has advanced significantly for many monogenic diseases of the hematopoietic system in recent years but has also…”
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5
Genes as Medicine: The Development of Gene Therapies for Inborn Errors of Immunity
Published in Hematology/oncology clinics of North America (01-08-2022)Get full text
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6
Novel Compound Heterozygote Variations in FADD Identified to Cause FAS-Associated Protein with Death Domain Deficiency
Published in Journal of clinical immunology (01-05-2020)Get full text
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7
Companion mass limits for 17 binary systems obtained with binary differential imaging and MagAO/Clio
Published in Monthly notices of the Royal Astronomical Society (11-08-2022)“…ABSTRACT Improving direct detection capability close to the star through improved star subtraction and post-processing techniques is vital for discovering new…”
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8
HIP 67506 C: MagAO-X confirmation of a new low-mass stellar companion to HIP 67506 A
Published in Monthly notices of the Royal Astronomical Society (01-05-2023)“…ABSTRACT We report the confirmation of HIP 67506 C, a new stellar companion to HIP 67506 A. We previously reported a candidate signal at 2λ/D (240 mas) in L′…”
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9
DNA contamination within recombinant adeno-associated virus preparations correlates with decreased CD34+ cell clonogenic potential
Published in Molecular therapy. Methods & clinical development (12-12-2024)“…Recombinant adeno-associated viruses (rAAV) are promising for applications in many genome editing techniques through their effectiveness as carriers of DNA…”
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10
Genes as Medicine
Published in Hematology/oncology clinics of North America (01-08-2022)Get full text
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The Effects of Bioinspired Infill Designs and Density on the Compressive Strength of Parts Produced by Additive Manufacturing via Fused Deposition Modeling
Published 01-01-2020“…The current state of additive manufacturing (AM) is still primarily used for prototyping and modeling. However, with the increase in available materials and…”
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Dissertation -
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Unlocking starlight subtraction in full data rate exoplanet imaging by efficiently updating Karhunen-Lo\`eve eigenimages
Published 27-01-2021“…Starlight subtraction algorithms based on the method of Karhunen-Lo\`eve eigenimages have proved invaluable to exoplanet direct imaging. However, they scale…”
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13
MagAO-X Phase II Upgrades: Implementation and First On-Sky Results of a New Post-AO 1000 Actuator Deformable Mirror
Published 17-07-2024“…MagAO-X is the extreme coronagraphic adaptive optics (AO) instrument for the 6.5-meter Magellan Clay telescope and is currently undergoing a comprehensive…”
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14
Experimental Trials With The Optical Differentiation Wavefront Sensor For Extended Objects
Published 17-08-2022“…Commonly used wavefront sensors, the Shack Hartmann wavefront sensor and the pyramid wavefront sensor, for example, have large dynamic range or high…”
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15
Challenge of direct imaging of exoplanets within structures: disentangling real signal from point source from background light
Published 18-07-2024“…The high contrast and spatial resolution requirements for directly imaging exoplanets requires effective coordination of wavefront control, coronagraphy,…”
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16
On-sky, real-time optical gain calibration on MagAO-X using incoherent speckles
Published 17-07-2024“…The next generation of extreme adaptive optics (AO) must be calibrated exceptionally well to achieve the desired contrast for ground-based direct imaging…”
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17
More data than you want, less data than you need: machine learning approaches to starlight subtraction with MagAO-X
Published 17-07-2024“…High-contrast imaging data analysis depends on removing residual starlight from the host star to reveal planets and disks. Most observers do this with…”
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18
MagAO-X: Commissioning Results and Status of Ongoing Upgrades
Published 17-07-2024“…MagAO-X is the coronagraphic extreme adaptive optics system for the 6.5 m Magellan Clay Telescope. We report the results of commissioning the first phase of…”
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19
Companion Mass Limits for 17 Binary Systems Obtained with Binary Differential Imaging and MagAO/Clio
Published 19-07-2022“…Improving direct detection capability close to the star through improved star-subtraction and post-processing techniques is vital for discovering new low-mass…”
Get full text
Journal Article -
20
MagAO-X and HST high-contrast imaging of the AS209 disk at H$\alpha
Published 22-08-2023“…The detection of emission lines associated with accretion processes is a direct method for studying how and where gas giant planets form, how young planets…”
Get full text
Journal Article