Search Results - "Long, Jeffrey D."

Joint modeling of multivariate longitudinal data and survival data in several observational studies of Huntington's disease by Long, Jeffrey D, Mills, James A

“…Joint modeling is appropriate when one wants to predict the time to an event with covariates that are measured longitudinally and are related to the event. An…”
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Huntington disease: natural history, biomarkers and prospects for therapeutics by Ross, Christopher A., Aylward, Elizabeth H., Wild, Edward J., Langbehn, Douglas R., Long, Jeffrey D., Warner, John H., Scahill, Rachael I., Leavitt, Blair R., Stout, Julie C., Paulsen, Jane S., Reilmann, Ralf, Unschuld, Paul G., Wexler, Alice, Margolis, Russell L., Tabrizi, Sarah J.

“…Key Points No disease-modifying treatments are currently available for Huntington disease (HD), but clinical trials of potential compounds are imminent;…”
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Deep learning for neuroimaging: a validation study by Plis, Sergey M, Hjelm, Devon R, Salakhutdinov, Ruslan, Allen, Elena A, Bockholt, Henry J, Long, Jeffrey D, Johnson, Hans J, Paulsen, Jane S, Turner, Jessica A, Calhoun, Vince D

“…Deep learning methods have recently made notable advances in the tasks of classification and representation learning. These tasks are important for brain…”
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Prediction of manifest Huntington's disease with clinical and imaging measures: a prospective observational study by Paulsen, Jane S, Dr Prof, Long, Jeffrey D, Prof, Ross, Christopher A, Prof, Harrington, Deborah L, Prof, Erwin, Cheryl J, JD, Williams, Janet K, Prof, Westervelt, Holly James, PhD, Johnson, Hans J, PhD, Aylward, Elizabeth H, PhD, Zhang, Ying, Prof, Bockholt, H Jeremy, BS, Barker, Roger A, Prof

“…Summary Background Although the association between cytosine-adenine-guanine (CAG) repeat length and age at onset of Huntington's disease is well known,…”
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Measuring compensation in neurodegeneration using MRI by Gregory, Sarah, Long, Jeffrey D, Tabrizi, Sarah J, Rees, Geraint

“…Despite signs of cortical and subcortical loss, patients with prodromal and early-stage neurodegenerative disease are able to perform at a level comparable to…”
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Acute Exercise Effects Predict Training Change in Cognition and Connectivity by VOSS, MICHELLE W., WENG, TIMOTHY B., NARAYANA-KUMANAN, KRITHIKA, COLE, RACHEL C., WHARFF, CONNER, REIST, LAUREN, DUBOSE, LYNDSEY, SIGURDSSON, GARDAR, MILLS, JAMES A., LONG, JEFFREY D., MAGNOTTA, VINCENT A., PIERCE, GARY L.

“…PURPOSEPrevious studies report memory and functional connectivity of memory systems improve acutely after a single aerobic exercise session or with training,…”
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Comprehensive shape analysis of the cortex in Huntington's disease by Stoebner, Zachary A., Hett, Kilian, Lyu, Ilwoo, Johnson, Hans, Paulsen, Jane S., Long, Jeffrey D., Oguz, Ipek

“…The striatum has traditionally been the focus of Huntington's disease research due to the primary insult to this region and its central role in motor symptoms…”
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The Interplay of Social Competence and Psychopathology Over 20 Years: Testing Transactional and Cascade Models by Burt, Keith B., Obradović, Jelena, Long, Jeffrey D., Masten, Ann S.

“…Associations among internalizing, externalizing, and social competence were examined in a longitudinal cohort (N = 205) of 8- to 12-year-old children…”
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Childhood Sexual Abuse and Early Timing of Puberty by Noll, Jennie G., Ph.D, Trickett, Penelope K., Ph.D, Long, Jeffrey D., Ph.D, Negriff, Sonya, Ph.D, Susman, Elizabeth J., Ph.D, Shalev, Idan, Ph.D, Li, Jacinda C., M.S, Putnam, Frank W., M.D

“…Abstract Purpose The purpose was to examine whether the timing of puberty, indexed by breast development and pubic hair development, was earlier for sexually…”
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The relationship of smoking to cg05575921 methylation in blood and saliva DNA samples from several studies by Dawes, Kelsey, Andersen, Allan, Reimer, Rachel, Mills, James A., Hoffman, Eric, Long, Jeffrey D., Miller, Shelly, Philibert, Robert

“…Numerous studies have shown that cg05575921 methylation decreases in response to smoking. However, secondary to methodological issues, the magnitude and dose…”
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DNA methylation differentiates smoking from vaping and non-combustible tobacco use by Andersen, Allan, Reimer, Rachel, Dawes, Kelsey, Becker, Ashley, Hutchens, Natasha, Miller, Shelly, Dogan, Meesha, Hundley, Brandon, A Mills, James, D Long, Jeffrey, Philibert, Robert

“…Increasing use of non-combusted forms of nicotine such as e-cigarettes poses important public health questions regarding their specific risks relative to…”
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Plasma 24S-hydroxycholesterol correlation with markers of Huntington disease progression by Leoni, Valerio, Long, Jeffrey D, Mills, James A, Di Donato, Stefano, Paulsen, Jane S

“…Abstract 24S-hydroxycholesterol (24OHC) is involved in the conversion of excess cholesterol in the brain, and its level in plasma is related to the number of…”
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ZSCAN25 methylation predicts seizures and severe alcohol withdrawal syndrome by Andersen, Allan, Milefchik, Emily, Papworth, Emma, Penaluna, Brandan, Dawes, Kelsey, Moody, Joanna, Weeks, Gracie, Froehlich, Ellyse, deBlois, Kaitlyn, Long, Jeffrey D, Philibert, Robert

“…Currently, clinicians use their judgement and indices such as the Prediction of Alcohol Withdrawal Syndrome Scale (PAWSS) to determine whether patients are…”
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Operationalizing compensation over time in neurodegenerative disease by Gregory, Sarah, Long, Jeffrey D, Klöppel, Stefan, Razi, Adeel, Scheller, Elisa, Minkova, Lora, Papoutsi, Marina, Mills, James A, Durr, Alexandra, Leavitt, Blair R, Roos, Raymund A C, Stout, Julie C, Scahill, Rachael I, Langbehn, Douglas R, Tabrizi, Sarah J, Rees, Geraint

“…In pre-clinical Huntington's disease, normal behaviour is maintained despite neurodegeneration, suggesting a mechanism of compensation. Gregory, Long et al …”
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Clustering and prediction of disease progression trajectories in Huntington's disease: An analysis of Enroll-HD data using a machine learning approach by Ko, Jinnie, Furby, Hannah, Ma, Xiaoye, Long, Jeffrey D, Lu, Xiao-Yu, Slowiejko, Diana, Gandhy, Rita

“…Huntington's disease (HD) is a rare neurodegenerative disease characterized by cognitive, behavioral and motor symptoms that progressively worsen with time…”
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Genetic Modification of Huntington Disease Acts Early in the Prediagnosis Phase by Long, Jeffrey D., Lee, Jong-Min, Aylward, Elizabeth H., Gillis, Tammy, Mysore, Jayalakshmi Srinidhi, Abu Elneel, Kawther, Chao, Michael J., Paulsen, Jane S., MacDonald, Marcy E., Gusella, James F.

“…Age at onset of Huntington disease, an inherited neurodegenerative disorder, is influenced by the size of the disease-causing CAG trinucleotide repeat…”
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Functional connectivity of the cerebellar vermis in bipolar disorder and associations with mood by Saleem, Arshaq, Harmata, Gail, Jain, Shivangi, Voss, Michelle W, Fiedorowicz, Jess G, Williams, Aislinn J, Shaffer, Joseph J, Richards, Jenny Gringer, Barsotti, Ercole John, Sathyaputri, Leela, Schmitz, Samantha L, Christensen, Gary E, Long, Jeffrey D, Xu, Jia, Wemmie, John A, Magnotta, Vincent A

“…Studies of the neural underpinnings of bipolar type I disorder have focused on the emotional control network. However, there is also growing evidence for…”
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Predictors of Smoking in Older Adults and an Epigenetic Validation of Self-Report by Long, Jeffrey D, Gehlsen, Michael P, Moody, Joanna, Weeks, Gracie, Philibert, Robert

“…There are several established predictors of smoking, but it is unknown if these predictors operate similarly for young and old smokers. We examined clinical…”
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Ranking the Predictive Power of Clinical and Biological Features Associated With Disease Progression in Huntington's Disease by Ghazaleh, Naghmeh, Houghton, Richard, Palermo, Giuseppe, Schobel, Scott A, Wijeratne, Peter A, Long, Jeffrey D

“…Huntington's disease (HD) is characterised by a triad of cognitive, behavioural, and motor symptoms which lead to functional decline and loss of independence…”
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The assessment of newborn iron stores at birth: a review of the literature and standards for ferritin concentrations by Siddappa, Ashajyothi M, Rao, Raghavendra, Long, Jeffrey D, Widness, John A, Georgieff, Michael K

“…Serum ferritin measurements are used in clinical populations to estimate total body iron stores and the risk of subsequent iron deficiency or overload. The…”
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