Search Results - "Long, James P"
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Detection method has independent prognostic significance in the PLCO lung screening trial
Published in Scientific reports (17-08-2023)“…Prognostic models in cancer use patient demographic and tumor characteristics to predict survival and dynamic disease prognosis. Past work in breast cancer has…”
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Lead-Time Trajectory of CA19-9 as an Anchor Marker for Pancreatic Cancer Early Detection
Published in Gastroenterology (New York, N.Y. 1943) (01-03-2021)“…There is substantial interest in liquid biopsy approaches for cancer early detection among subjects at risk, using multi-marker panels. CA19-9 is an…”
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3
Active tuning of surface phonon polariton resonances via carrier photoinjection
Published in Nature photonics (01-01-2018)“…Surface phonon polaritons (SPhPs) are attractive alternatives to infrared plasmonics for subdiffractional confinement of infrared light. Localized SPhP…”
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Low-Loss, Extreme Subdiffraction Photon Confinement via Silicon Carbide Localized Surface Phonon Polariton Resonators
Published in Nano letters (14-08-2013)“…Plasmonics provides great promise for nanophotonic applications. However, the high optical losses inherent in metal-based plasmonic systems have limited…”
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5
Quantitative Imaging of Protein Secretions from Single Cells in Real Time
Published in Biophysical journal (06-08-2013)“…Protein secretions from individual cells create spatially and temporally varying concentration profiles in the extracellular environment, which guide a wide…”
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6
Electronic Hybridization of Large-Area Stacked Graphene Films
Published in ACS nano (22-01-2013)“…Direct, tunable coupling between individually assembled graphene layers is a next step toward designer two-dimensional (2D) crystal systems, with relevance for…”
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7
Pathological complete response of adding targeted therapy to neoadjuvant chemotherapy for inflammatory breast cancer: A systematic review
Published in PloS one (16-04-2021)“…The current use of targeted therapy plus neoadjuvant chemotherapy for inflammatory breast cancer (IBC) is based on data extrapolated from studies in non-IBC…”
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Whole Genome-Derived Tiled Peptide Arrays Detect Prediagnostic Autoantibody Signatures in Non-Small-Cell Lung Cancer
Published in Cancer research (Chicago, Ill.) (01-04-2019)“…The majority of non-small-cell lung cancer (NSCLC) cases are diagnosed at advanced stages, primarily because earlier stages of the disease are either…”
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Early and sustained innate immune response defines pathology and death in nonhuman primates infected by highly pathogenic influenza virus
Published in Proceedings of the National Academy of Sciences - PNAS (03-03-2009)“…The mechanisms responsible for the virulence of the highly pathogenic avian influenza (HPAI) and of the 1918 pandemic influenza virus in humans remain poorly…”
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10
Experimental demonstration of the optical lattice resonance in arrays of Si nanoresonators
Published in Applied physics letters (14-03-2016)“…Optical resonances of crystalline Si nanopillar arrays on a Si substrate are studied using optical reflectivity and Raman spectroscopy. When the nanopillars…”
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Natural History of Marburg Virus Infection to Support Medical Countermeasure Development
Published in Viruses (01-10-2022)“…The Biomedical Advanced Research and Development Authority, part of the Administration for Strategic Preparedness and Response within the U.S. Department of…”
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A Comprehensive Search of Non-Canonical Proteins in Non-Small Cell Lung Cancer and Their Impact on the Immune Response
Published in International journal of molecular sciences (11-08-2022)“…There is substantial interest in mining neoantigens for cancer applications. Non-canonical proteins resulting from frameshift mutations have been identified as…”
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Urinary T cells are detected in patients with immune checkpoint inhibitor-associated immune nephritis that are clonotypically identical to kidney T cell infiltrates
Published in Oncoimmunology (2022)“…Acute kidney injury (AKI) occurs in ~20% of patients receiving immune checkpoint inhibitor (ICI) therapy; however, only 2-5% will develop ICI-mediated immune…”
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Profiling of patients with glioma reveals the dominant immunosuppressive axis is refractory to immune function restoration
Published in JCI insight (03-09-2020)“…In order to prioritize available immune therapeutics, immune profiling across glioma grades was conducted, followed by preclinical determinations of…”
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A first-in-human Phase I trial of the oral p-STAT3 inhibitor WP1066 in patients with recurrent malignant glioma
Published in CNS oncology (01-06-2022)“…To ascertain the maximum tolerated dose (MTD)/maximum feasible dose (MFD) of WP1066 and p-STAT3 target engagement within recurrent glioblastoma (GBM) patients…”
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Application of Artificial Intelligence to Plasma Metabolomics Profiles to Predict Response to Neoadjuvant Chemotherapy in Triple-Negative Breast Cancer
Published in Frontiers in artificial intelligence (11-08-2022)“…There is a need to identify biomarkers predictive of response to neoadjuvant chemotherapy (NACT) in triple-negative breast cancer (TNBC). We previously…”
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Quantitative LSPR Imaging for Biosensing with Single Nanostructure Resolution
Published in Biophysical journal (08-01-2013)“…Localized surface plasmon resonance (LSPR) imaging has the potential to map complex spatio-temporal variations in analyte concentration, such as those produced…”
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A New Methodology for Quantitative LSPR Biosensing and Imaging
Published in Analytical chemistry (Washington) (07-02-2012)“…A new quantitative analysis methodology for localized surface plasmon resonance (LSPR) biosensing which determines surface-receptor fractional occupancy, as…”
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Clinical profiles associated with influenza disease in the ferret model
Published in PloS one (05-03-2013)“…Influenza A viruses continue to pose a threat to human health; thus, various vaccines and prophylaxis continue to be developed. Testing of these products…”
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Natural History of Sudan ebolavirus to Support Medical Countermeasure Development
Published in Vaccines (Basel) (16-06-2022)“…Sudan ebolavirus (SUDV) is one of four members of the Ebolavirus genus known to cause Ebola Virus Disease (EVD) in humans, which is characterized by…”
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