Search Results - "Long, Idris"

Editorial: Common pathways in neurodevelopmental conditions and neurodegenerative disorders by Long, Idris

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Protective effects of Centella asiatica extract on spatial memory and learning deficits in animal model of systemic inflammation induced by lipopolysaccharide by Md Pisar, Mazura, Chee, Beng Jin, Long, Idris, Osman, Asiah

“…Centella asiatica (L.) Urb. (Apiaceae) is a renowned medicinal plant being used in the Ayurvedic system for its pharmacological effects on the central nervous…”
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Minocycline Attenuates Lipopolysaccharide-Induced Locomotor Deficit and Anxiety-like Behavior and Related Expression of the BDNF/CREB Protein in the Rat Medial Prefrontal Cortex (mPFC) by Abdo Qaid, Entesar Yaseen, Abdullah, Zuraidah, Zakaria, Rahimah, Long, Idris

“…Neuroinflammation following lipopolysaccharide (LPS) administration induces locomotor deficits and anxiety-like behaviour. In this study, minocycline was…”
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Effects of different doses of complete Freund's adjuvant on nociceptive behaviour and inflammatory parameters in polyarthritic rat model mimicking rheumatoid arthritis by Noh, Ain' Sabreena Mohd, Chuan, Tan Dai, Khir, Nurul Ajilah Mohamed, Zin, Anani Aila Mat, Ghazali, Anis Kausar, Long, Idris, Ab Aziz, Che Badariah, Ismail, Che Aishah Nazariah

“…Complete Freund's adjuvant (CFA) has been used to develop the arthritic or inflammatory condition in the animal, but there is a lack of information concerning…”
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Tannins in the Treatment of Diabetic Neuropathic Pain: Research Progress and Future Challenges by Omar, Norsuhana, Ismail, Che Aishah Nazariah, Long, Idris

“…Diabetes mellitus and its consequences continue to put a significant demand on medical resources across the world. Diabetic neuropathic pain (DNP) is a…”
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In Silico Analyses and Cytotoxicity Study of Asiaticoside and Asiatic Acid from Malaysian Plant as Potential mTOR Inhibitors by Zulkipli, Ninie Nadia, Zakaria, Rahimah, Long, Idris, Abdullah, Siti Fadilah, Muhammad, Erma Fatiha, Wahab, Habibah A, Sasongko, Teguh Haryo

“…Natural products remain a popular alternative treatment for many ailments in various countries. This study aimed to screen for potential mammalian target of…”
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Impact of Rapid Eye Movement Sleep Deprivation on Pain Behaviour and Oxidative Stress in the Thalamus: Role of Tualang Honey Supplementation by Anis Syahirah, Mohd Shafie, Che Badariah, Abd Aziz, Idris, Long, Rosfaiizah, Siran, Liza, Noordin

“…Insufficient sleep alters the body's physiological functions. This study investigated whether oxidative stress (OS) in the thalamus was correlated with the…”
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Increased Nociceptive Responses in Streptozotocin-Induced Diabetic Rats and the Related Expression of Spinal NR2B Subunit of N -Methyl-D-Aspartate Receptors by Ismail, Che Aishah Nazariah, Suppian, Rapeah, Abd Aziz, Che Badariah, Haris, Khalilah, Long, Idris

“…This study investigated the role of NR2B in a modulated pain process in the painful diabetic neuropathy (PDN) rat using various pain stimuli. Thirty-two…”
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The Effects of Pre-emptive Administration of Ketamine and norBNI on Pain Behavior, c-Fos, and Prodynorphin Protein Expression in the Rat Spinal Cord after Formalin-induced Pain Is Modulated by the DREAM Protein by Long, Idris, Suppian, Rapeah, Ismail, Zalina

“…We investigated the effects of pre-emptive administration of ketamine and norBNI on pain behavior and the expression of DREAM, c-Fos, and prodynorphin proteins…”
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Minocycline mitigates tau pathology via modulating the TLR-4/NF-кβ signalling pathway in the hippocampus of neuroinflammation rat model by Abdo Qaid, Entesar Yaseen, Abdullah, Zuraidah, Zakaria, Rahimah, Long, Idris

“…The neuroinflammatory response was seen to impact the formation of phosphorylated tau protein in Alzheimer's disease (AD). This study aims to investigate the…”
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Minocycline Protects Against Lipopolysaccharide-Induced Cognitive Impairment and Oxidative Stress: Possible Role of the CREB-BDNF Signaling Pathway by Qaid, Entesar Yaseen Abdo, Abdullah, Zuraidah, Zakaria, Rahimah, Long, Idris

“…The oxidative stress-induced dysregulation of the cyclic AMP response element-binding protein- brain-derived neurotrophic factor (CREB-BDNF) cascade has been…”
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Comparative Effects of Indomethacin and Nabumetone on Urine and Electrolyte Output in Conscious Rats by Long, Idris bin, Jeet Singh, Harbindar, Janardhana Rao, Gurubelli

“…The effects of indomethacin and nabumetone on urine and electrolyte excretion in conscious rats were examined. Male Sprague-Dawley rats were housed…”
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The Effects of Pre-emptive Administration of Ketamine and norBNI on Pain Behavior, c-Fos, and Prodynorphin Protein Expression in the Rat Spinal Cord after Formalin-induced Pain Is Modulated by the DREAM Protein by Long, Idris, Suppian, Rapeah, Ismail, Zalina

“…Background: We investigated the effects of pre-emptive administration of ketamine and norBNI on pain behavior and the expression of DREAM, c-Fos, and…”
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Minocycline protects against lipopolysaccharide-induced glial cells activation and oxidative stress damage in the medial prefrontal cortex (mPFC) of the rat by Abdo Qaid, Entesar Yaseen, Abdullah, Zuraidah, Zakaria, Rahimah, Long, Idris

“…Neuroinflammation and oxidative stress have been encountered in neurodegenerative diseases such as Alzheimer's disease (AD). However, the neuroprotective…”
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Recent progress on anti-nociceptive effects of carbon monoxide releasing molecule-2 (CORM-2) by Khir, Nurul Ajilah Mohamed, Noh, Ain’ Sabreena Mohd, Long, Idris, Zakaria, Rahimah, Ismail, Che Aishah Nazariah

“…The role of carbon monoxide (CO) has evolved albeit controversial disputes on its toxicity. This biological gasotransmitter participates in the endogenous…”
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Minocycline Ameliorated LPS-Induced Learning and Memory Impairment by Inhibiting Microglia and Astrocytes Activation in The Hippocampus by Long, Idris, Abdo Qaid, Entesar Yaseen, Abdullah, Zuraidah, Zakaria, Rahimah

“…INTRODUCTION: Many studies support the notion that neuroinflammation involving glial cells may be the fundamental pathogenic event that lead to brain damage…”
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Expressions of spinal microglia activation, BDNF, and DREAM proteins correlated with formalin-induced nociceptive responses in painful and painless diabetic neuropathy rats by Ismail, Che Aishah Nazariah, Suppian, Rapeah, Ab Aziz, Che Badariah, Long, Idris

“…The complications of diabetic polyneuropathy (DN) determines its level of severity. It may occur with distinctive clinical symptoms (painful DN) or appears…”
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Diabetes and cognitive decline: Challenges and future direction by Ab-Hamid, Norhamidar, Omar, Norsuhana, Ismail, Che Aishah Nazariah, Long, Idris

“…There is growing evidence that diabetes can induce cognitive decline and dementia. It is a slow, progressive cognitive decline that can occur in any age group,…”
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Inflammatory-associated apoptotic markers: are they the culprit to rheumatoid arthritis pain? by Khir, Nurul Ajilah Mohamed, Noh, Ain’ Sabreena Mohd, Long, Idris, Ismail, Norjihada Izzah, Siran, Rosfaiizah, Ismail, Che Aishah Nazariah

“…Background Rheumatoid arthritis (RA) is a prolonged inflammatory disease resulting from autoimmune reactions that leads to local and systemic bone erosion,…”
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Lower Formalin-Induced Pain Responses in Painless Diabetic Neuropathy Rat Correlate with the Reduced Spinal Cord NR2B Subunit of N-Methyl-D-Aspartate Receptor Activation by Ismail, Che Aishah Nazariah, Ghazali, Anis Kausar, Suppian, Rapeah, Abd Aziz, Che Badariah, Long, Idris

“…Diabetic neuropathy (DN) is a late complication of diabetic mellitus and may rise into painful and painless variants. Limited studies have looked at…”
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