Search Results - "Long, Gregory J"
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Routine, Cost-Effective SARS-CoV-2 Surveillance Testing Using Pooled Saliva Limits Viral Spread on a Residential College Campus
Published in Microbiology spectrum (31-10-2021)“…Routine testing for SARS-CoV-2 is rare for institutes of higher education due to prohibitive costs and supply chain delays. During spring 2021, we routinely…”
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Lead induced rise in intracellular free calcium is mediated through activation of protein kinase C in osteoblastic bone cells
Published in Biochimica et biophysica acta (24-05-1997)“…Lead characteristically perturbs processes linked to the calcium messenger system. This study was undertaken to determine the role of PKC in the Pb 2+ induced…”
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The Effect of Cadmium on Cytosolic Free Calcium, Protein Kinase C, and Collagen Synthesis in Rat Osteosarcoma (ROS 17/2.8) Cells
Published in Toxicology and applied pharmacology (01-03-1997)“…Cadmium affects normal bone growth but the mechanisms of Cd2+toxicity are not fully understood. Calcium is an integral component of bone growth and a second…”
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Cellular and Molecular Toxicity of Lead in Bone
Published in Environmental health perspectives (01-02-1991)“…To fully understand the significance of bone as a target tissue of lead toxicity, as well as a reservoir of systemic lead, it is necessary to define the…”
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Cadmium perturbs calcium homeostasis in rat osteosarcoma (ros 17/2.8) cells; a possible role for protein kinase c
Published in Toxicology letters (28-04-1997)“…The mechanism of the toxic effects of Cd 2+ on bone cell function is not completely understood at this time. This study was designed to characterize the effect…”
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Lead perturbs 1,25 dihydroxyvitamin D3 modulation of intracellular calcium metabolism in clonal rat osteoblastic (ROS 17/2.8) cells
Published in Life sciences (1973) (1994)“…1,25-Dihydroxyvitamin D3 (1,25(OH)2D3) is known to modulate Ca2+ metabolism in several cell types. 1,25(OH)2D3 causes an increase in Ca2+ influx and probably…”
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Lead perturbs epidermal growth factor (EGF) modulation of intracellular calcium metabolism and collagen synthesis in clonal rat osteoblastic (ROS 17/2.8) cells
Published in Toxicology and applied pharmacology (01-05-1992)“…EGF, a single-chain polypeptide growth factor important for many cellular functions including glycolysis and protein phosphorylation, is known to modulate…”
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Lead impairs the production of osteocalcin by rat osteosarcoma (ROS 17/2.8) cells
Published in Toxicology and applied pharmacology (01-11-1990)“…The serum level of osteocalcin, a bone-specific protein produced by osteoblasts and an index of bone formation, is decreased in lead-intoxicated children. To…”
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Lead intoxication alters basal and parathyroid hormone-regulated cellular calcium homeostasis in rat osteosarcoma (ROS 17/2.8) cells
Published in Calcified tissue international (01-05-1992)“…The skeleton is the major reservoir of lead and calcium in humans, and plays an important role in systemic calcium regulation. Lead perturbs normal calcium…”
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Cellular lead toxicity and metabolism in primary and clonal osteoblastic bone cells
Published in Toxicology and applied pharmacology (01-02-1990)“…A knowledge of bone lead metabolism is critical for understanding the toxicological importance of bone lead, as a toxicant both to bone cells and to soft…”
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