Search Results - "Long, Gregory J"

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    Lead induced rise in intracellular free calcium is mediated through activation of protein kinase C in osteoblastic bone cells by Schanne, Francis A.X, Long, Gregory J, Rosen, John F

    Published in Biochimica et biophysica acta (24-05-1997)
    “…Lead characteristically perturbs processes linked to the calcium messenger system. This study was undertaken to determine the role of PKC in the Pb 2+ induced…”
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    Journal Article
  3. 3

    The Effect of Cadmium on Cytosolic Free Calcium, Protein Kinase C, and Collagen Synthesis in Rat Osteosarcoma (ROS 17/2.8) Cells by Long, Gregory J.

    Published in Toxicology and applied pharmacology (01-03-1997)
    “…Cadmium affects normal bone growth but the mechanisms of Cd2+toxicity are not fully understood. Calcium is an integral component of bone growth and a second…”
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  4. 4

    Cellular and Molecular Toxicity of Lead in Bone by Pounds, Joel G., Long, Gregory J., Rosen, John F.

    Published in Environmental health perspectives (01-02-1991)
    “…To fully understand the significance of bone as a target tissue of lead toxicity, as well as a reservoir of systemic lead, it is necessary to define the…”
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  5. 5

    Cadmium perturbs calcium homeostasis in rat osteosarcoma (ros 17/2.8) cells; a possible role for protein kinase c by Long, Gregory J.

    Published in Toxicology letters (28-04-1997)
    “…The mechanism of the toxic effects of Cd 2+ on bone cell function is not completely understood at this time. This study was designed to characterize the effect…”
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  6. 6

    Lead perturbs 1,25 dihydroxyvitamin D3 modulation of intracellular calcium metabolism in clonal rat osteoblastic (ROS 17/2.8) cells by Long, G J, Rosen, J F

    Published in Life sciences (1973) (1994)
    “…1,25-Dihydroxyvitamin D3 (1,25(OH)2D3) is known to modulate Ca2+ metabolism in several cell types. 1,25(OH)2D3 causes an increase in Ca2+ influx and probably…”
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  7. 7

    Lead perturbs epidermal growth factor (EGF) modulation of intracellular calcium metabolism and collagen synthesis in clonal rat osteoblastic (ROS 17/2.8) cells by Long, G J, Rosen, J F

    Published in Toxicology and applied pharmacology (01-05-1992)
    “…EGF, a single-chain polypeptide growth factor important for many cellular functions including glycolysis and protein phosphorylation, is known to modulate…”
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  8. 8

    Lead impairs the production of osteocalcin by rat osteosarcoma (ROS 17/2.8) cells by Long, G J, Rosen, J F, Pounds, J G

    Published in Toxicology and applied pharmacology (01-11-1990)
    “…The serum level of osteocalcin, a bone-specific protein produced by osteoblasts and an index of bone formation, is decreased in lead-intoxicated children. To…”
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  9. 9

    Lead intoxication alters basal and parathyroid hormone-regulated cellular calcium homeostasis in rat osteosarcoma (ROS 17/2.8) cells by LONG, G. J, POUNDS, J. G, ROSEN, J. F

    Published in Calcified tissue international (01-05-1992)
    “…The skeleton is the major reservoir of lead and calcium in humans, and plays an important role in systemic calcium regulation. Lead perturbs normal calcium…”
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  10. 10

    Cellular lead toxicity and metabolism in primary and clonal osteoblastic bone cells by Long, G J, Rosen, J F, Pounds, J G

    Published in Toxicology and applied pharmacology (01-02-1990)
    “…A knowledge of bone lead metabolism is critical for understanding the toxicological importance of bone lead, as a toxicant both to bone cells and to soft…”
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