Search Results - "Long, Dani M"

The amyloid precursor protein intracellular domain induces sleep disruptions and its nuclear localization fluctuates in circadian pacemaker neurons in Drosophila and mice by Long, Dani M., Cravetchi, Olga, Chow, Eileen S., Allen, Charles, Kretzschmar, Doris

“…The most prominent symptom of Alzheimer's disease (AD) is cognitive decline; however, sleep and other circadian disruptions are also common in AD patients…”
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FTD-associated mutations in Tau result in a combination of dominant and recessive phenotypes by Law, Alexander D., Cassar, Marlène, Long, Dani M., Chow, Eileen S., Giebultowicz, Jadwiga M., Venkataramanan, Anjana, Strauss, Roland, Kretzschmar, Doris

“…Although mutations in the microtubules-associated protein Tau have long been connected with several neurodegenerative diseases, the underlying molecular…”
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Age-Related Changes in the Expression of the Circadian Clock Protein PERIOD in Drosophila Glial Cells by Long, Dani M, Giebultowicz, Jadwiga M

“…Circadian clocks consist of molecular negative feedback loops that coordinate physiological, neurological, and behavioral variables into "circa" 24-h rhythms…”
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Chlorogenic Acids, Acting via Calcineurin, Are the Main Compounds in Centella asiatica Extracts That Mediate Resilience to Chronic Stress in Drosophila melanogaster by Holvoet, Helen, Long, Dani M, Yang, Liping, Choi, Jaewoo, Marney, Luke, Poeck, Burkhard, Maier, Claudia S, Soumyanath, Amala, Kretzschmar, Doris, Strauss, Roland

“…Common symptoms of depressive disorders include anhedonia, sleep problems, and reduced physical activity. Drugs used to treat depression mostly aim to increase…”
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Withania somnifera Extracts Promote Resilience against Age-Related and Stress-Induced Behavioral Phenotypes in Drosophila melanogaster; a Possible Role of Other Compounds besides Withanolides by Holvoet, Helen, Long, Dani M., Law, Alexander, McClure, Christine, Choi, Jaewoo, Yang, Liping, Marney, Luke, Poeck, Burkhard, Strauss, Roland, Stevens, Jan F., Maier, Claudia S., Soumyanath, Amala, Kretzschmar, Doris

“…Withania somnifera (WS) extracts have been used in traditional medicine for millennia to promote healthy aging and wellbeing. WS is now also widely used in…”
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Relationships between the circadian system and Alzheimer's disease-like symptoms in Drosophila by Long, Dani M, Blake, Matthew R, Dutta, Sudeshna, Holbrook, Scott D, Kotwica-Rolinska, Joanna, Kretzschmar, Doris, Giebultowicz, Jadwiga M

“…Circadian clocks coordinate physiological, neurological, and behavioral functions into circa 24 hour rhythms, and the molecular mechanisms underlying circadian…”
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Withania somnifera and Centella asiatica Extracts Ameliorate Behavioral Deficits in an In Vivo Drosophila melanogaster Model of Oxidative Stress by Cabey, Kadine, Long, Dani M, Law, Alexander, Gray, Nora E, McClure, Christine, Caruso, Maya, Lak, Parnian, Wright, Kirsten M, Stevens, Jan F, Maier, Claudia S, Soumyanath, Amala, Kretzschmar, Doris

“…Due to an increase in the aging population, age-related diseases and age-related changes, such as diminished cognition and sleep disturbances, are an…”
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Lactate dehydrogenase expression modulates longevity and neurodegeneration in Drosophila melanogaster by Long, Dani M, Frame, Ariel K, Reardon, Patrick N, Cumming, Robert C, Hendrix, David A, Kretzschmar, Doris, Giebultowicz, Jadwiga M

“…Lactate dehydrogenase (LDH) catalyzes the conversion of glycolysis-derived pyruvate to lactate. Lactate has been shown to play key roles in brain energetics…”
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Circadian rhythm in mRNA expression of the glutathione synthesis gene Gclc is controlled by peripheral glial clocks in Drosophila melanogaster by Chow, Eileen S., Long, Dani M., Giebultowicz, Jadwiga M.

“…Circadian coordination of metabolism, physiology and behaviour is found in all living kingdoms. Clock genes are transcriptional regulators, and their rhythmic…”
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Aging and circadian rhythms by Giebultowicz, Jadwiga M, Long, Dani M

“…•Circadian clocks are well understood in young fruit flies but less is known about how they change during aging.•Sleep/activity rhythms decay in aging while…”
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Chlorogenic Acids, Acting via Calcineurin, Are the Main Compounds in ICentella asiatica/I Extracts That Mediate Resilience to Chronic Stress in IDrosophila melanogaster/I by Holvoet, Helen, Long, Dani M, Yang, Liping, Choi, Jaewoo, Marney, Luke, Poeck, Burkhard, Maier, Claudia S, Soumyanath, Amala, Kretzschmar, Doris, Strauss, Roland

“…Common symptoms of depressive disorders include anhedonia, sleep problems, and reduced physical activity. Drugs used to treat depression mostly aim to increase…”
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IWithania somnifera/I Extracts Promote Resilience against Age-Related and Stress-Induced Behavioral Phenotypes in IDrosophila melanogaster;/I a Possible Role of Other Compounds besides Withanolides by Holvoet, Helen, Long, Dani M, Law, Alexander, McClure, Christine, Choi, Jaewoo, Yang, Liping, Marney, Luke, Poeck, Burkhard, Strauss, Roland, Stevens, Jan F, Maier, Claudia S, Soumyanath, Amala, Kretzschmar, Doris

“…Withania somnifera (WS) extracts have been used in traditional medicine for millennia to promote healthy aging and wellbeing. WS is now also widely used in…”
Get full text