Search Results - "Lonergan, David"

FAK promotes stromal PD-L2 expression associated with poor survival in pancreatic cancer by Davidson, Catherine, Taggart, David, Sims, Andrew H., Lonergan, David W., Canel, Marta, Serrels, Alan

“…Background Pancreatic Cancer is one of the most lethal cancers, with less than 8% of patients surviving 5 years following diagnosis. The last 40 years have…”
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FAK suppresses antigen processing and presentation to promote immune evasion in pancreatic cancer by Canel, Marta, Sławińska, Aleksandra Dominika, Lonergan, David W, Kallor, Ashwin Adrian, Upstill-Goddard, Rosie, Davidson, Catherine, von Kriegsheim, Alex, Biankin, Andrew V, Byron, Adam, Alfaro, Javier, Serrels, Alan

“…Immunotherapy for the treatment of pancreatic ductal adenocarcinoma (PDAC) has shown limited efficacy. Poor CD8 T-cell infiltration, low neoantigen load and a…”
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T-cell co-stimulation in combination with targeting FAK drives enhanced anti-tumor immunity by Canel, Marta, Taggart, David, Sims, Andrew H, Lonergan, David W, Waizenegger, Irene C, Serrels, Alan

“…Focal Adhesion Kinase (FAK) inhibitors are currently undergoing clinical testing in combination with anti-PD-1 immune checkpoint inhibitors. However, which…”
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FAK promotes stromal PD-L2 expression associated with poor survival in pancreatic cancer by Davidson, Catherine, Taggart, David, Sims, Andrew H., Lonergan, David W., Canel, Marta, Serrels, Alan

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Identification of 4‑(Aminomethyl)-6-(trifluoromethyl)-2-(phenoxy)pyridine Derivatives as Potent, Selective, and Orally Efficacious Inhibitors of the Copper-Dependent Amine Oxidase, Lysyl Oxidase-Like 2 (LOXL2) by Rowbottom, Martin W, Bain, Gretchen, Calderon, Imelda, Lasof, Taylor, Lonergan, David, Lai, Andiliy, Huang, Fei, Darlington, Janice, Prodanovich, Patricia, Santini, Angelina M, King, Christopher D, Goulet, Lance, Shannon, Kristen E, Ma, Gina L, Nguyen, Katherine, MacKenna, Deidre A, Evans, Jilly F, Hutchinson, John H

“…LOXL2 catalyzes the oxidative deamination of ε-amines of lysine and hydroxylysine residues within collagen and elastin, generating reactive aldehydes…”
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Have Ability, Won't Travel by Lonergan, David

“…This article discusses the sad state of affairs in academic recruitment and retention--of library upper management. Anyone who has taken part in searches for…”
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Basics of a Library Film Collection by Lonergan, David

“…This paper discusses the advantages of a film library as compared with other possible methods of providing films to academic programs and individual viewers,…”
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BTX-1188, a first-in-class dual degrader of GSPT1 and IKZF1/3, for treatment of acute myeloid leukemia (AML) and solid tumors by Chourasia, Aparajita Hoskote, Majeski, Hannah, Pasis, Angela, Erdman, Paul, Oke, Ashwini, Hecht, David, Lonergan, David, Mercurio, Frank, Chan, Kyle, Thai, Dung Luong, Fung, Leah

“…7025 Background: BTX-1188 is a first-in-class oral molecular glue that degrades GSPT1 and IKZF1/3 and is currently in phase 1 clinical trials for treatment of…”
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How to Get Published, Part IV: The Book by Lonergan, David

“…The earlier entries in this series have, among other things, discussed the motives that may lead librarians into writing and publishing, how one may choose…”
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How to Get Published, Part III by Lonergan, David

“…A very high proportion of librarians are neither required to publish nor rewarded if they do. The would-be librarian/writer would be well advised to take a…”
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A Moment in Time by Lonergan, David

“…There is a growing literature on the disappearance of the traditional model of higher education. Fewer courses are taught now than was the case just a few…”
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How to Get Published, Part II by Lonergan, David

“…Some job descriptions of academic librarians, tenure track or otherwise, will emphasize publication, while in others, it is essentially an irrelevant factor…”
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FAK suppresses antigen processing and presentation to promote immune evasion in pancreatic cancer by Serrels, Alan, Canel, Marta, Slawinska, Aleksandra, Lonergan, David W., Kallor, Ashwin Adrian, Upstill-Goddard, Rosie, Davidson, Catherine, von Kriegsheim, Alex, Biankin, Andrew V., Byron, Adam, Alfaro, Javier, Serrels, Alan

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A remarkable adenine-binding cleft based on a hydroxyimide scaffold by Lonergan, David G, Deslongchamps, Ghislain, Tomàs, Salvador

“…The synthesis and binding properties of a molecular cleft for adenine recognition based on a new hydroxyimide scaffold is described. NMR titration experiments…”
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Management by Staying Put by Lonergan, David

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Popular Culture in the Junior College Library by Lonergan, David, Ayers, Meredith

“…Popular culture is extremely influential in both academe and society at large. However, formal disciplinary study of popular culture lags far behind that…”
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Small Molecule Lysyl Oxidase-like 2 (LOXL2) Inhibitors: The Identification of an Inhibitor Selective for LOXL2 over LOX by Hutchinson, John H, Rowbottom, Martin W, Lonergan, David, Darlington, Janice, Prodanovich, Pat, King, Christopher D, Evans, Jilly F, Bain, Gretchen

“…Two series of novel LOXL2 enzyme inhibitors are described: benzylamines substituted with electron withdrawing groups at the para-position and 2-substituted…”
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Natural Disasters and Man-Made Catastrophes by Lonergan, David

“…This article categorizes and discusses the kinds of cataclysmic events that threaten the human race and the natural world. A useful set of definitions is…”
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Tricyclic scaffolds for the rapid assembly of abiotic receptors by Lonergan, David G., Deslongchamps, Ghislain

“…The design and synthesis of tricyclic scaffolds for the modular assembly of abiotic receptors soluble in organic solvent is described. Their application to the…”
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Taylor-Made Libraries by Lonergan, David

“…Frederick Winslow Taylor (1856-1915) was an efficiency expert whose concerns were less about avoiding worker fatigue and more about increasing profit margins…”
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