Current profile and management of gonococcal infections: A population-based study in Western France

•This population-based study of 245 patients with documented gonococcal infections in Western France in 2014–2016, found that:.•Almost 50% of cases are diagnosed by a general practitioner;.•The main clinical presentations include urethritis and pelvic inflammatory disease;.•Antibacterial treatment w...

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Bibliographic Details
Published in:	Infectious diseases now (Online) Vol. 51; no. 2; pp. 201 - 204
Main Authors:	Loncle, Adrien, Piau, Caroline, Ndeikoundam Ngangro, Ndeindo, Gousseff, Marie, Cattoir, Vincent, Allory, Emmanuel, Lorléac, Aurélien, Dupont, Mathieu, Goubard, Agathe, Tattevin, Pierre
Format:	Journal Article
Language:	English
Published:	Elsevier Masson SAS 01-03-2021 Elsevier
Subjects:	General practitioner Life Sciences Neisseria gonorrhea Population-based study Population-based study General practitioner Neisseria gonorrhea
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Summary:	•This population-based study of 245 patients with documented gonococcal infections in Western France in 2014–2016, found that:.•Almost 50% of cases are diagnosed by a general practitioner;.•The main clinical presentations include urethritis and pelvic inflammatory disease;.•Antibacterial treatment was appropriate in 100% of urethritis cases, and<50% of pelvic inflammatory diseases. To characterize the current profile of gonococcal infections in France, and to describe their management. A population-based retrospective study of all gonococcal infections documented by PCR in two French departments (Île-et-Vilaine, Morbihan), in 2014–2016. Cases were identified through hospital databases and the Rénago sentinel network. We enrolled 245 patients (96 females, 149 males), with a median age of 25 years [interquartile range, 21–33]. The incidence rate was estimated at 4.54 per 100,000 inhabitants-year. Cases were diagnosed mostly by a general practitioner (n=122, 49.8%) or a gynecologist (n=45, 18.4%). The main clinical presentations included urethritis (n=59), pelvic inflammatory disease (n=40), cervicitis (n=12), and anorectitis (n=11). The main coinfections were Chlamydia trachomatis (n=40) and HIV (n=8). Ceftriaxone MIC was≤0.12mg/L in 146/147 patients with positive culture. Treatment was appropriate in 52/74 (70.2%) patients with available data. In France, general practitioners are at the front line in management of gonococcal infections.
ISSN:	2666-9919 2666-9919
DOI:	10.1016/j.idnow.2020.11.010