Search Results - "Lomnicka, M"
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1
1‐Methylnicotinamide (MNA), a primary metabolite of nicotinamide, exerts anti‐thrombotic activity mediated by a cyclooxygenase‐2/prostacyclin pathway
Published in British journal of pharmacology (01-09-2007)“…Background and purpose: 1‐methylnicotinamide (MNA) has been considered to be an inactive metabolite of nicotinamide. Here we assessed the anti‐thrombotic…”
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2
Endothelial action of thienopyridines and thienopyrimidinones in the isolated guinea pig heart
Published in Prostaglandins, leukotrienes and essential fatty acids (01-02-2005)“…Antiplatelet thienopyridines (ticlopidine, clopidogrel) and their thienopyrimidinone congeners, induce prostacyclin-dependent thrombolysis in vivo. Here we…”
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3
The involvement of adhesion molecules and lipid mediators in the adhesion of human platelets to eosinophils
Published in Journal of physiology and pharmacology : an official journal of the Polish Physiological Society (01-12-2005)“…Platelet-leukocyte interactions represent an important determinant of the inflammatory response. Although mechanisms of platelet-neutrophil adhesion were…”
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4
Reversal of the postischaemic suppression of coronary function in perfused guinea pig heart by ischaemic preconditioning
Published in Journal of physiology and pharmacology : an official journal of the Polish Physiological Society (01-12-1999)“…In the isolated guinea pig hearts suppression of endothelium-dependent (Acetylcholine, Substance P, postocclusive hyperaemia) and endothelium-independent…”
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5
Carbon monoxide released by CORM-3 inhibits human platelets by a mechanism independent of soluble guanylate cyclase
Published in Cardiovascular research (15-07-2006)“…Carbon monoxide (CO) modulates several physiological functions through activation of a cGMP-dependent pathway similar to that of nitric oxide (NO). Here we…”
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6
Ischaemic cardiac hyperaemia: role of nitric oxide and other mediators
Published in Physiological research (1996)“…In the perfused guinea-pig heart reactive hyperaemia (RH) after occlusion of coronary flow (1-60 s) was inhibited by 100-60% with NG-nitro-L-arginine (100…”
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7
Why do cyclo-oxygenase-2 inhibitors cause cardiovascular events?
Published in Journal of the American College of Cardiology (06-02-2002)“…This report confirms evidence that selective nonsteroidal anti-inflammatory drugs (NSAIDs), such as celecoxib, can lead to thrombotic cardiovascular events…”
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8
Obligatory role of lipid mediators in platelet–neutrophil adhesion
Published in Thrombosis research (15-06-2003)“…Platelet–neutrophil interactions play an important role in thrombotic and inflammatory responses. Although it is well known that adhesion of platelets to…”
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9
Comparison of Endothelial Pleiotropic Actions of Angiotensin Converting Enzyme Inhibitors and Statins
Published in Annals of the New York Academy of Sciences (01-12-2001)“…: Two in vitro and one in vivo assay were performed to study the endothelial pleiotropic actions of “tissue type” angiotensin converting enzyme inhibitors…”
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10
Hypertriglyceridemia but not hypercholesterolemia induces endothelial dysfunction in the rat
Published in Pharmacological reports (01-01-2005)“…In humans, hypercholesterolemia and hypertriglyceridemia induce endothelial dysfunction and therefore lead to atherosclerosis. In contrast, rats are resistant…”
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11
Permeability of nitric oxide through lipid bilayer membranes
Published in Free radical research (01-01-1996)“…Profiles of the local nitric oxide (.NO) diffusion-concentration product across the egg yolk phosphatidylcholine membrane in the absence and presence of 30…”
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12
Effects of nonsteroidal anti-inflammatory drugs on prostacyclin and thromboxane in the kidney
Published in Pharmacology (01-07-2003)“…Dose-response curves were obtained relating the effects of increasing amounts of aspirin, a nonselective cyclooxygenase (COX) inhibitor, and celecoxib, a…”
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13
L-N6-(1-iminoethyl)-lysine (L-NIL) but not S-methylisothiourea sulphate (SMT) displays selectivity towards NOS-2
Published in Polish journal of pharmacology (01-09-1999)“…Our aim was to verify potency and selectiveness of two most widely used drugs regarded as NOS-2 inhibitors: L-N6-(1-iminoethyl)-lysine (L-NIL) and…”
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