Search Results - "Lombrozo, L"

Mesolimbic dopaminergic supersensitivity following electrical kindling of the amygdala by Csernansky, J G, Mellentin, J, Beauclair, L, Lombrozo, L

“…Limbic seizures developed in rats following daily electrical stimulation of the basolateral nucleus of the amygdala. Animals were designated as "kindled" after…”
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Sensitization versus tolerance to the dopamine turnover-elevating effects of haloperidol: the effect of regular/intermittent dosing by Csernansky, J G, Bellows, E P, Barnes, D E, Lombrozo, L

“…Recent clinical research suggests that particular patterns of changes in presynaptic dopamine (DA) turnover accompany the therapeutic response to neuroleptics…”
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Effects of raclopride treatment on plasma and CSF HVA : relationships with clinical improvement in male schizophrenics by CSERNANSKY, J. G, NEWCOMER, J. W, JACKSON, K, LOMBROZO, L, FAULL, K. F, ZIPURSKY, R, PFEFFERBAUM, A, FAUSTMAN, W. O

“…Thirty-two acutely psychotic, male schizophrenic patients received raclopride, at 2, 6, or 12 mg/day, or haloperidol, 15 mg/day for 4 weeks after randomized,…”
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Haloperidol kinetics after oral and intravenous doses by Holley, F O, Magliozzi, J R, Stanski, D R, Lombrozo, L, Hollister, L E

“…Haloperidol kinetics were determined after oral and intravenous drug doses in 15 men. Mean elimination t1/2 for the subjects was 17.9 +/- 6.4 (SD) hr. After…”
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Correlates of rapid neuroleptic response in male patients with schizophrenia by Petrie, E C, Faustman, W O, Moses, J A, Lombrozo, L, Csernansky, J G

“…Correlates of neuroleptic response latency were assessed in 16 male schizophrenic inpatients during 4 weeks of fixed dose (20 mg/day) haloperidol treatment…”
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A microassay for measuring synaptosomal 3H-dopamine and 3H-metabolite release by Petrie, E C, Lombrozo, L, Csernansky, J G

“…A modified synaptosomal superfusion apparatus is described which uses less than 10 micrograms of tissue per replicate sample and facilitates the routine…”
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Interrelationships between plasma homovanillic acid and indices of dopamine turnover in multiple brain areas during haloperidol and saline administration by Csernansky, J G, Barnes, D E, Bellows, E P, Lombrozo, L

“…Haloperidol or saline was administered to rats daily for 1, 8, 15 or 22 days. During haloperidol, but not saline administration, changes in plasma homovanillic…”
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Treatment of negative schizophrenic symptoms with alprazolam: a preliminary open-label study by Csernansky, J G, Lombrozo, L, Gulevich, G D, Hollister, L E

“…Eight schizophrenic patients received alprazolam in an open-label protocol. A partial reversal of negative symptoms was noted in six of the eight patients…”
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Mood alteration following oral and intravenous haloperidol and relationship to drug concentration in normal subjects by Magliozzi, J R, Gillespie, H, Lombrozo, L, Hollister, L E

“…Haloperidol was administered to 12 subjects intravenously (0.125 mg/kg) and to nine subjects orally (0.5 mg/kg). These doses produced sedation in most…”
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Circadian variations of lorazepam-induced neurologic deficits by Henauer, S, Lombrozo, L, Hollister, L E

“…Circadian variations of lorazepam-induced neurologic deficits were tested in mice. The duration of the impairment after administration of 3 mg/kg lorazepam was…”
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Effect of caffeine on hepatic microsomal cytochrome P-450 by Lombrozo, L, Mitoma, C

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Functional tolerance to alprazolam-induced neurologic deficits in mice by Henauer, S A, Lombrozo, L, Hollister, L E

“…Tolerance to alprazolam-induced neurologic deficits was assessed in mice by a rotarod test. Tolerance was found following a second administration of 2 mg/kg…”
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Plasma concentrations of thiothixene and clinical response in treatment-resistant schizophrenics by Hollister, L E, Lombrozo, L, Huang, C C

“…Plasma concentrations of thiothixene were measured during treatment of 42 treatment-resistant schizophrenic patients. Inter-individual variability was marked…”
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Modification of assays for the routine analysis of 3-methoxy-4-hydroxyphenylglycol in urine by electron-capture gas chromatography by Lombrozo, L, Anderson, T J, Kanaske, K, Hollister, L E

“…Urinary 3-methoxy-4-hydroxyphenylglycol has been reliably assayed on a routine basis using an electron-capture detector method. Modifications of previous…”
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Nature of the effect of caffeine on the drug-metabolizing enzymes by Mitoma, C, Lombrozo, L, LeValley, S E, Dehn, F

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VI. Separation of cannabinoids by sequential thin layer chromatography by Lombrozo, L, Kanter, S L, Hollister, L E

“…Using a series of solvent systems, one neutral and non-polar, another basic and a third acidic, in a sequential thin layer chromatography (TLC) scheme we…”
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MICROELECTROPHORESIS OF BRAIN AND PINEAL PROTEINS IN POLYACRYLAMIDE GEL by PUN, J Y, LOMBROZO, L

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Studies on N5,N10-methenyltetrahydrofolate cyclohydrolase by Lombrozo, L, Greenberg, D M

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Double-blind comparison of alprazolam, diazepam, and placebo for the treatment of negative schizophrenic symptoms by Csernansky, J G, Riney, S J, Lombrozo, L, Overall, J E, Hollister, L E

“…Fifty-five schizophrenic outpatients with negative symptoms were treated for up to six weeks by the addition of alprazolam (mean dose, 4.2 mg/d), diazepam…”
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Correlation of initial thiothixene serum levels and clinical response. Comparison of fluorometric, gas chromatographic, and RBC assays by Yesavage, J A, Holman, C A, Cohn, R, Lombrozo, L

“…A series of three experiments addressed major problems concerning the use of serum levels as predictors of clinical response to thiothixene (Navane)…”
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