Search Results - "Lomax, J"

Human-chimpanzee differences in a FZD8 enhancer alter cell-cycle dynamics in the developing neocortex by Boyd, J Lomax, Skove, Stephanie L, Rouanet, Jeremy P, Pilaz, Louis-Jan, Bepler, Tristan, Gordân, Raluca, Wray, Gregory A, Silver, Debra L

“…The human neocortex differs from that of other great apes in several notable regards, including altered cell cycle, prolonged corticogenesis, and increased…”
Get full text

Intensity modulated proton therapy and its sensitivity to treatment uncertainties 2: the potential effects of inter-fraction and inter-field motions by Lomax, A J

“…Simple tools for studying the effects of inter-fraction and inter-field motions on intensity modulated proton therapy (IMPT) plans have been developed, and…”
Get more information

Intensity modulated proton therapy and its sensitivity to treatment uncertainties 1: the potential effects of calculational uncertainties by Lomax, A J

“…The effects of calculational uncertainties on 3D and distal edge tracking (DET) intensity modulated proton therapy (IMPT) treatment plans have been…”
Get more information

Towards FLASH proton therapy: the impact of treatment planning and machine characteristics on achievable dose rates by van de Water, Steven, Safai, Sairos, Schippers, Jacobus M, Weber, Damien C, Lomax, Antony J

“…This study aimed at evaluating spatially varying instantaneous dose rates for different intensity-modulated proton therapy (IMPT) planning strategies and…”
Get more information

Embodied Neural Systems Can Enable Iterative Investigations of Morally Relevant States by Kagan, Brett J, Loeffler, Alon, Boyd, J Lomax, Savulescu, Julian

“…Kagan et al discuss the use of embodied neural systems, which can enable iterative investigations of morally relevant states. The development of intelligent…”
Get full text

Commissioning of a clinical pencil beam scanning proton therapy unit for ultra‐high dose rates (FLASH) by Nesteruk, Konrad P., Togno, Michele, Grossmann, Martin, Lomax, Anthony J., Weber, Damien C., Schippers, Jacobus M., Safai, Sairos, Meer, David, Psoroulas, Serena

“…Purpose The purpose of this work was to provide a flexible platform for FLASH research with protons by adapting a former clinical pencil beam scanning gantry…”
Get full text

Limitations of phase-sorting based pencil beam scanned 4D proton dose calculations under irregular motion by Duetschler, A, Prendi, J, Safai, S, Weber, D C, Lomax, A J, Zhang, Ye

“…4D dose calculation (4DDC) for pencil beam scanned (PBS) proton therapy is typically based on phase-sorting of individual pencil beams onto phases of a single…”
Get more information

Consensus Statement on Proton Therapy in Early-Stage and Locally Advanced Non–Small Cell Lung Cancer by Chang, Joe Y., MD, PhD, Jabbour, Salma K., MD, De Ruysscher, Dirk, MD, Schild, Steven E., MD, Simone, Charles B., MD, Rengan, Ramesh, MD, Feigenberg, Steven, MD, Khan, Atif J., MD, Choi, Noah C., MD, Bradley, Jeffrey D., MD, Zhu, Xiaorong R., PhD, Lomax, Antony J., PhD, Hoppe, Bradford S., MD

“…Radiation dose escalation has been shown to improve local control and survival in patients with non–small cell lung cancer in some studies, but randomized data…”
Get full text

Toward Responsible Public Engagement in Neuroethics by Boyd, J. Lomax, Sugarman, Jeremy

Get full text

Comparative study of layered and volumetric rescanning for different scanning speeds of proton beam in liver patients by Bernatowicz, K, Lomax, A J, Knopf, A

“…In recent years, particle therapy has become a widely accepted form of cancer treatment and technological advances in beam delivery technology (i.e. pencil…”
Get more information

Differential DNA repair pathway choice in cancer cells after proton- and photon-irradiation by Fontana, Andrea O, Augsburger, Marc A, Grosse, Nicole, Guckenberger, Matthias, Lomax, Anthony J, Sartori, Alessandro A, Pruschy, Martin N

“…Abstract Background and purpose Non-homologous end-joining (NHEJ) and homologous recombination (HR) contribute to the repair of irradiation-induced DNA…”
Get full text

Intensity modulated proton therapy plan generation in under ten seconds by Matter, Michael, Nenoff, Lena, Meier, Gabriel, Weber, Damien C, Lomax, Antony J, Albertini, Francesca

“…Treatment planning for intensity modulated proton therapy (IMPT) can be significantly improved by reducing the time for plan calculation, facilitating…”
Get more information

Effect of Anatomic Changes on Pencil Beam Scanned Proton Dose Distributions for Cranial and Extracranial Tumors by Placidi, Lorenzo, MSc, Bolsi, Alessandra, MSc, Lomax, Antony J., PhD, Schneider, Ralf A., MD, Malyapa, Robert, MD, PhD, Weber, Damien C., MD, PhD, Albertini, Francesca, PhD

“…Purpose To estimate the frequency and impact of anatomic changes on the delivered dose in pencil beam scanning proton therapy, to assess the need for repeat CT…”
Get full text

Effectiveness and Safety of Spot Scanning Proton Radiation Therapy for Chordomas and Chondrosarcomas of the Skull Base: First Long-Term Report by Ares, Carmen, M.D, Hug, Eugen B., M.D, Lomax, Antony J., Ph.D, Bolsi, Alessandra, M.Sc, Timmermann, Beate, M.D, Rutz, Hans Peter, M.D, Schuller, Jan C., Ph.D, Pedroni, Eros, Ph.D, Goitein, Gudrun, M.D

“…Purpose To evaluate effectiveness and safety of spot-scanning-based proton radiotherapy (PT) in skull-base chordomas and chondrosarcomas. Methods and Materials…”
Get full text

Systematic evaluation of three different commercial software solutions for automatic segmentation for adaptive therapy in head-and-neck, prostate and pleural cancer by La Macchia, Mariangela, Fellin, Francesco, Amichetti, Maurizio, Cianchetti, Marco, Gianolini, Stefano, Paola, Vitali, Lomax, Antony J, Widesott, Lamberto

“…To validate, in the context of adaptive radiotherapy, three commercial software solutions for atlas-based segmentation. Fifteen patients, five for each group,…”
Get full text

An Analysis of Plan Robustness for Esophageal Tumors: Comparing Volumetric Modulated Arc Therapy Plans and Spot Scanning Proton Planning by Warren, Samantha, PhD, Partridge, Mike, PhD, Bolsi, Alessandra, PhD, Lomax, Anthony J., PhD, Hurt, Chris, PhD, Crosby, Thomas, FRCR, Hawkins, Maria A., FRCR

“…Purpose Planning studies to compare x-ray and proton techniques and to select the most suitable technique for each patient have been hampered by the…”
Get full text

Acute management of autoimmune toxicity in cancer patients on immunotherapy: Common toxicities and the approach for the emergency physician by Lomax, Anna J, McNeil, Catriona

“…When a patient receiving anti‐cancer treatment presents acutely unwell, an understanding of associated side effects of their therapy is critical. This review…”
Get full text

Impact of internal target volume definition for pencil beam scanned proton treatment planning in the presence of respiratory motion variability for lung cancer: A proof of concept by Krieger, Miriam, Giger, Alina, Salomir, Rares, Bieri, Oliver, Celicanin, Zarko, Cattin, Philippe C., Lomax, Antony J., Weber, Damien C., Zhang, Ye

“…•Conventional 4DCT based ITV volumes vary substantially in presence of respiration variability.•4D plan quality (target coverage and dose homogeneity) strongly…”
Get full text

Experimental verification of motion mitigation of discrete proton spot scanning by re-scanning by Schätti, A, Zakova, M, Meer, D, Lomax, A J

“…In order to be able to treat mobile tumours with active, scanned proton therapy, adequate motion mitigation techniques have to be applied. Re-scanning is such…”
Get more information

Spot-Scanning Proton Radiation Therapy for Pediatric Chordoma and Chondrosarcoma: Clinical Outcome of 26 Patients Treated at Paul Scherrer Institute by Rombi, Barbara, MD, Ares, Carmen, MD, Hug, Eugen B., MD, Schneider, Ralf, MD, Goitein, Gudrun, MD, Staab, Adrian, MD, Albertini, Francesca, PhD, Bolsi, Alessandra, MSc, Lomax, Antony J., PhD, Timmermann, Beate, MD

“…Purpose To evaluate the clinical results of fractionated spot-scanning proton radiation therapy (PT) in 26 pediatric patients treated at Paul Scherrer…”
Get full text