Search Results - "Lomax, Charlotte"
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Methylated arsenic species in plants originate from soil microorganisms
Published in The New phytologist (01-02-2012)“…• Inorganic arsenic (iAs) is a ubiquitous human carcinogen, and rice (Oryza sativa) is the main contributor to iAs in the diet. Methylated pentavalent As…”
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Breeding Novel Chemistry in Willow: New Hetero Diels-Alder Cyclodimers from Arbusculoidin and Salicortin Suggest Parallel Biosynthetic Pathways
Published in Plants (Basel) (11-06-2024)“…An investigation of phenolic glycosides extracted from germplasm revealed that arbusculoidin (benzyl 1- -β-d-glucopyranosyl-1-hydroxy-6-oxo-2-cyclohexenyl…”
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A willow UDP-glycosyltransferase involved in salicinoid biosynthesis
Published in Journal of experimental botany (27-02-2021)“…The salicinoids are phenolic glycosides that are characteristic secondary metabolites of the Salicaceae, particularly willows and poplars. Despite the…”
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Diverting phenylpropanoid pathway flux from sinapine to produce industrially useful 4-vinyl derivatives of hydroxycinnamic acids in Brassicaceous oilseeds
Published in Metabolic engineering (01-03-2022)“…Sinapine (sinapoylcholine) is an antinutritive phenolic compound that can account for up to 2% of seed weight in brassicaceous oilseed crops and reduces the…”
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5
Inhibitors of α‑Synuclein Fibrillation and Oligomer Toxicity in Rosa damascena: The All-Pervading Powers of Flavonoids and Phenolic Glycosides
Published in ACS chemical neuroscience (07-10-2020)“…There is an intense search for natural compounds that can inhibit the oligomerization and fibrillation of α-synuclein (α-Syn), whose aggregation is key to the…”
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Miyabeacin: A new cyclodimer presents a potential role for willow in cancer therapy
Published in Scientific reports (15-04-2020)“…Willow (Salix spp.) is well known as a source of medicinal compounds, the most famous being salicin, the progenitor of aspirin. Here we describe the isolation,…”
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Oleuropein derivatives from olive fruit extracts reduce α-synuclein fibrillation and oligomer toxicity
Published in The Journal of biological chemistry (15-03-2019)“…Aggregation of α-synuclein (αSN) is implicated in neuronal degeneration in Parkinson's disease and has prompted searches for natural compounds inhibiting αSN…”
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Salicin-7-sulfate: A new salicinoid from willow and implications for herbal medicine
Published in Fitoterapia (01-06-2018)“…Willow (Salix sp.) is a historically well-known herbal medicine that provided the lead compound (salicin) for the discovery of aspirin, one of the most…”
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Investigating the origin and transport of methylated arsenic species in plants
Published 01-01-2013“…Inorganic arsenic is a toxic element known to cause various diseases and cancers in humans. Arsenic contamination is widespread worldwide, particularly in…”
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Dissertation