Search Results - "Lomas, Chip"
-
1
Abstract 3201: Single-cell trajectory analysis reveals a melanoma-driven distinct hematopoietic response in murine spleen
Published in Cancer research (Chicago, Ill.) (01-07-2021)“…Abstract Growing evidence suggests that tumor progression can interfere with normal hematopoiesis and skew the host system to undergo myeloid biased changes…”
Get full text
Journal Article -
2
Single-cell trajectory analysis reveals a melanoma-driven distinct hematopoietic response in murine spleen
Published in The Journal of immunology (1950) (01-05-2021)“…Abstract Hematopoietic stem and progenitor cells (HSPCs) are a rare population of precursor cells residing in bone marrow that replenish blood cells throughout…”
Get full text
Journal Article -
3
Abstract 4967: Leveraging the power of high parameter cell sorting and single-cell multi-omics to profile intratumoral immune cells in a model of B-cell lymphoma
Published in Cancer research (Chicago, Ill.) (15-08-2020)“…Abstract As for most neoplasms, the pathogenesis and progression of B-cell malignancies is a dynamic process involving reciprocal interactions between…”
Get full text
Journal Article -
4
A Performance-Optimized Multicolor Flow Cytometry Dried-Reagent Cocktail for Memory T-Cell Analysis
Published in The Journal of immunology (1950) (01-05-2020)“…Abstract The reliance on flow cytometry for phenotypical and functional analyses of immune components in both research and clinical laboratories has increased…”
Get full text
Journal Article -
5
Leveraging the power of high parameter cell sorting and single-cell multi-omics to profile intratumoral immune cells in a model of B cell lymphoma
Published in The Journal of immunology (1950) (01-05-2020)“…Abstract The pathogenesis and progression of B-cell lymphomas is a dynamic process involving reciprocal interactions between malignant cells and surrounding…”
Get full text
Journal Article -
6
Abstract 3310: Resolving the heterogeneity of human circulating innate lymphoid cells via simultaneous, high-dimensional analysis of protein and gene expression
Published in Cancer research (Chicago, Ill.) (15-08-2020)“…Abstract Cancer treatment has been revolutionized with the development of immunomodulatory therapies. These therapies have primarily focused on enhancing…”
Get full text
Journal Article -
7
Resolving the heterogeneity of human circulating innate lymphoid cells via simultaneous, high-dimensional analysis of protein and gene expression
Published in The Journal of immunology (1950) (01-05-2020)“…Abstract Cancer treatment has been revolutionized with the development of immunomodulatory therapies. While these therapies have primarily focused on enhancing…”
Get full text
Journal Article -
8
Abstract 2431: Single cell gene expression profiling in breast cancer cells with the Her2/neu gene knockout by CRISPR-Cas9
Published in Cancer research (Chicago, Ill.) (01-07-2017)“…Abstract The Her2/neu gene is amplified and overexpressed in 15%-30% of breast cancers. The overexpression of this oncogene is strongly correlated with…”
Get full text
Journal Article -
9
EpCAM based capture detects and recovers circulating tumor cells from all subtypes of breast cancer except claudin-low
Published in Oncotarget (29-12-2015)“…The potential utility of circulating tumor cells (CTCs) as liquid biopsies is of great interest. We hypothesized that CTC capture using EpCAM based gating is…”
Get full text
Journal Article -
10
Control of the Fluorescence of Dye–Antibody Conjugates by (2-Hydroxypropyl)-β-cyclodextrin in Fluorescence Microscopy and Flow Cytometry
Published in Analytical chemistry (Washington) (15-09-2011)“…When proteins are conjugated to fluorescent organic dyes, fluorescence emission of the dye molecules is usually decreased, sometimes up to 50–70%. This…”
Get full text
Journal Article -
11
Control of the Fluorescence of Dye-Antibody Conjugates by (2-Hydroxypropyl)-[Beta]-cyclodextrin in Fluorescence Microscopy and Flow Cytometry
Published in Analytical chemistry (Washington) (15-09-2011)“…When proteins are conjugated to fluorescent organic dyes, fluorescence emission of the dye molecules is usually decreased, sometimes up to 50-70%. This…”
Get full text
Journal Article -
12
ID: 1027 High-Throughput, Single Cell Whole Transcriptome Sequencing Analysis of Cancer Cells with the New BD FACSMelody™ Cell Sorter and BD™ Precise assay
Published in Biomedical research and therapy (05-09-2017)“…Gene expression studies performed on bulk samples might obscure the understanding of complex samples. Gene expression analyses performed on single cells,…”
Get full text
Journal Article -
13
ID: 1070 Single-Cell Gene Expression Profiling in Breast Cancer Cells with the HER2/neu Gene Knockout by CRISPR-Cas9
Published in Biomedical research and therapy (05-09-2017)“…The HER2/neu gene is amplified and overexpressed in 15–30% of breast cancers. The overexpression of this oncogene is strongly correlated with decreased…”
Get full text
Journal Article