Search Results - "Lomaia, E G"
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Cepeginterferon alfa-2b in the treatment of chronic myeloproliferative diseases
Published in Terapevtic̆eskii arhiv (17-08-2018)“…A comparative evaluation of the effectiveness of different therapeutic strategies in patients with polycythemia vera (PV) and essential thrombocythemia (ET)…”
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Retrospective analysis of own long-term experience in studying the BCR::ABL kinase domain mutational status in patients with chronic myeloid leukemia
Published in Onkogematologii͡a (01-09-2024)“…Background . Most patients with chronic myeloid leukemia (CML) treated with tyrosine kinase inhibitors achieve durable optimal responses. Loss of the achieved…”
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CASC5 Gene Expression Changes Correlate with Targeted Mutations in Leukemia
Published in Molecular biology (New York) (2021)“…Dysfunction of genes that control mitosis and are responsible for the correct segregation of sister chromatids in anaphase is often accompanied by aneuploidy,…”
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Change of concentration of biochemical markers of dysfunction of endothelium at intake of inhibitors of tyrosinekinase of I and II generations at patients with a chronic myeloid leukemia as risk factor of development of cardiovascular complications
Published in Rossiĭskiĭ kardiologicheskiĭ zhurnal (11-01-2021)“…CML), the accepting inhibitors tyrosine of kinases (TKI) I and the II generations (TKI1 and TKI2 respectively), and development of arterial hypertension…”
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Identification of oncogene mutations in leukemia patients using microchip-based PCR analysis
Published in Russian journal of bioorganic chemistry (01-09-2017)“…At present, cytogenetic and PCR-based techniques are generally used in the diagnosis of leukemia. Due to high accuracy, specificity, and sensitivity of PCR…”
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CLINICAL AND LABORATORY FEATURES OF ESSENTIAL THROMBOCYTOSIS AND PRIMARY MYELOFIBROSIS DEPENDING ON JAK2 AND CALR1 MUTATION STATUS
Published in Onkogematologii͡a (01-10-2017)“…Introduction. JAK2V617F mutation is detected in approximately 50 % of patients with essential thrombocytosis (ET) and primary myelofibrosis (PMF). In 2013 most…”
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Quality of life, symptom profile and clinical efficacy of second-line treatment with dasatinib in patients with imatinib-resistant or -intolerant chronic myeloid leukemia: results of 2-year follow-up
Published in Onkogematologii͡a (07-10-2015)“…The article is focused on the results of the multicenter observational study “Quality of life and symptom profile in patients with chronic myeloid leukemia in…”
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Ponatinib dose-ranging study in chronic-phase chronic myeloid leukemia: a randomized, open-label phase 2 clinical trial
Published in Blood (25-11-2021)“…In PACE (Ponatinib Ph+ ALL and CML Evaluation), a phase 2 trial of ponatinib that included patients with chronic-phase chronic myeloid leukemia (CP-CML)…”
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Chronic myeloid leukemia — before and after imatinib (First part)
Published in Onkogematologii͡a (01-11-2022)“…The first successful experience effective target therapy has been achieved at imatinib administration in chronic myeloid leukemia (CML) treatment. Disease…”
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Chronic myeloid leukemia — before and after imatinib (Third part)
Published in Onkogematologii͡a (01-11-2022)“…Imatinib (IM) appearance has changed approaches to chronic myeloid leukemia (CML) therapy. Second generation tyrosine kinase inhibitors (TKI) — nilotinib and…”
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Nilotinib - new step of success in CML therapy
Published in Onkogematologii͡a (01-11-2022)Get full text
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CASC5 Gene Expression Changes Correlate with Targeted Mutations in Leukemia
Published in Molekuliarnaia biologiia (01-01-2021)“…Dysfunction of genes that control mitosis and are responsible for the correct segregation of sister chromatids in anaphase is often accompanied by aneuploidy,…”
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CML-047 Post Hoc Analysis of Responses to Ponatinib in Patients With Chronic-Phase Chronic Myeloid Leukemia (CP-CML) by Baseline BCR::ABL1 Level and Baseline Mutation Status in the OPTIC Trial
Published in Clinical lymphoma, myeloma and leukemia (01-10-2022)“…Objectives: OPTIC (NCT02467270) is a Phase 2 trial evaluating the safety and efficacy of ponatinib in patients with CP-CML resistant to ≥2 TKIs or have a T315I…”
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Chronic myeloid leukemia — before and after imatinib (part II)
Published in Onkogematologii͡a (01-11-2022)Get full text
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Efficacy and safety of tyrosine kinase inhibitors (dasatinib, nilotinib) in the treatment of chronic phase chronic myeloid leukemia
Published in Onkogematologii͡a (01-07-2014)“…Current treatment options for chronic myeloid leukemia (CML) with imatinib allowed achieving long-term progression-free and overall survival and improved…”
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Efficacy and safety of tyrosine kinase inhibitors (dasatinib, nilotinib) in the treatment of chronic phase chronic myeloid leukemia
Published in Onkogematologii͡a (01-07-2014)“…Current treatment options for chronic myeloid leukemia (CML) with imatinib allowed achieving long-term progression-free and overall survival and improved…”
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Prognosis factors in imatinib mesilate therapy in patients with a chronic phase of Ph-positive chronic myeloid leukemia: data from a multicenter non-randomized trial in Russia
Published in Terapevtic̆eskii arhiv (2007)“…To reveal prognostically significant factors affecting efficacy of glivek therapy in untreated (duration of the disease < or = 6 months) and pretreated…”
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