Search Results - "Lolli, Ivan"
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1
Crohn’s Disease Following Rituximab Treatment for Follicular Lymphoma in a Patient with Synchronous Gastric Signet Ring Cells Carcinoma: A Case Report and Literature Review
Published in Cancer research and treatment (01-10-2020)“…Recently, there have been a few reports of rituximab (RTX)-induced Crohn’s disease, but there is no literature available on successful long-term treatment and…”
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2
Unexpected response to palliative radiotherapy for subcutaneous metastases of an advanced small cell pancreatic neuroendocrine carcinoma: a case report of two different radiation schedules
Published in BMC cancer (15-04-2020)“…Skin metastases from pancreatic neuroendocrine carcinoma (PNEC) are rare and their palliative treatment is challenging. We report our experience in the…”
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Randomised phase II trial of CAPTEM or FOLFIRI as SEcond-line therapy in NEuroendocrine CArcinomas and exploratory analysis of predictive role of PET/CT imaging and biological markers (SENECA trial): a study protocol
Published in BMJ open (19-07-2020)“…IntroductionPatients with metastatic or locally advanced, non-resectable, grade 3 poorly differentiated gastroenteropancreatic (GEP) and lung neuroendocrine…”
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Quality of life, compliance, safety and effectiveness in fit older metastatic colorectal patients with cancer treated in first-line with chemotherapy plus cetuximab: A restrospective analysis from the ObservEr study
Published in Journal of geriatric oncology (01-05-2018)“…The influence of age (<70 years and ≥70 years) was retrospectively studied on the quality of life (QoL), incidence of side effects (including skin reactions)…”
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Observational study on quality of life, safety, and effectiveness of first‐line cetuximab plus chemotherapy in KRAS wild‐type metastatic colorectal cancer patients: the ObservEr Study
Published in Cancer medicine (Malden, MA) (01-11-2016)“…Cetuximab improves efficacy when added to chemotherapy for metastatic colorectal cancer (mCRC). Effective management of skin reactions from cetuximab improves…”
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Corrigendum: Variations in circulating levels of angiopoietin-2 over time are predictive of ramucirumab-paclitaxel therapy outcome in advanced gastric cancer: results of prospective study
Published in Frontiers in oncology (14-04-2023)“…[This corrects the article DOI: 10.3389/fonc.2022.862116.]…”
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Variations in Circulating Levels of Angiopoietin-2 Over Time Are Predictive of Ramucirumab-Paclitaxel Therapy Outcome in Advanced Gastric Cancer: Results of Prospective Study
Published in Frontiers in oncology (06-04-2022)“…The combination of paclitaxel and ramucirumab is the second-line therapy of choice in the treatment of advanced gastric cancer. To date, no biomarkers are…”
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A retrospective pooled analysis of response patterns and risk factors in recurrent malignant glioma patients receiving a nitrosourea-based chemotherapy
Published in Journal of translational medicine (14-05-2012)“…At recurrence the use of nitrosoureas is widely-used as a therapeutic option for glioblastoma (GBM) patients. The efficacy of fotemustine (FTM) has been…”
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9
Long lasting octreotide LAR therapy in non functioning pancreatic neuroendocrine carcinoma
Published in Clinical management issues (13-10-2015)“…Non functioning endocrine pancreatic tumors (NF-PETs) have absent or low hormone secretion without symptoms and constitue ~60% of PETs. At diagnosis more than…”
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10
A ruptured gastrointestinal stromal tumour of the small intestine: a case report
Published in Clinical management issues (13-10-2015)“…The management of Gastrointestinal Stromal Tumours (GISTs) has evolved rapidly since imatinib was introduced. Surgery remains the first-line treatment for…”
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11
Epidermal growth factor receptor serum levels and prognostic value in malignant gliomas
Published in Tumori (01-05-2007)“…The epidermal growth factor receptor (EGFR) is a member of a family of cell membrane receptors that use tyrosine kinase activity as the signal transduction…”
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Regorafenib compared with lomustine in patients with relapsed glioblastoma (REGOMA): a multicentre, open-label, randomised, controlled, phase 2 trial
Published in The lancet oncology (01-01-2019)“…Glioblastoma is a highly vascularised tumour and there are few treatment options after disease recurrence. Regorafenib is an oral multikinase inhibitor of…”
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Anaplastic Classic Kaposi Sarcoma: PD-L1 Expression and Response to Immunotherapy: A Case Report and Review of the Literature
Published in Journal of the National Comprehensive Cancer Network (01-05-2023)“…Anaplastic classic Kaposi sarcoma (CKS) is an extremely rare pathologic variant of CKS characterized by high aggressiveness and poor prognosis. We report the…”
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Molecular mechanisms of synergistic action of Ramucirumab and Paclitaxel in Gastric Cancers cell lines
Published in Scientific reports (28-04-2020)“…Ramucirumab is approved both as monotherapy and in combination with Paclitaxel for advanced gastric cancer in patients with disease progression after…”
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A molecular signature associated with prolonged survival in glioblastoma patients treated with regorafenib
Published in Neuro-oncology (Charlottesville, Va.) (25-02-2021)“…Abstract Background Patients with glioblastoma (GBM) have a dramatically poor prognosis. The recent REGOMA trial suggested an overall survival (OS) benefit of…”
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Patient-reported outcomes in a phase II randomised study of regorafenib compared with lomustine in patients with relapsed glioblastoma (the REGOMA trial)
Published in European journal of cancer (1990) (01-09-2021)“…The REGOMA trial showed that regorafenib significantly improved overall survival in patients with recurrent glioblastoma compared with lomustine. Patients…”
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Phosphorylated Acetyl-CoA Carboxylase Is Associated with Clinical Benefit with Regorafenib in Relapsed Glioblastoma: REGOMA Trial Biomarker Analysis
Published in Clinical cancer research (01-09-2020)“…Preclinical studies show that antiangiogenic therapy exacerbates tumor glycolysis and activates liver kinase B1/AMP kinase (AMPK), a pathway involved in the…”
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18
A randomized phase II trial of Captem or Folfiri as second-line therapy in neuroendocrine carcinomas
Published in European journal of cancer (1990) (01-09-2024)“…Neuroendocrine Carcinomas (NECs) prognosis is poor.No standard second-line therapy is currently recognized after failure of platinum-based first-line…”
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Bevacizumab and fotemustine for recurrent glioblastoma: a phase II study of AINO (Italian Association of Neuro-Oncology)
Published in Journal of neuro-oncology (01-02-2014)“…The optimal combination of bevacizumab with cytotoxic or cytostatic drugs in recurrent glioblastoma is unknown. We performed a phase 2 trial of combined…”
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Intermittent or continuous panitumumab plus FOLFIRI (FOLFIRI/PANI) for first-line treatment of patients (pts) with RAS/BRAF wild-type (wt) metastatic colorectal cancer (mCRC): An update of survival/toxicity and preliminary results of genomic alterations from IMPROVE study
Published in Journal of clinical oncology (01-06-2023)“…3571 Background: IMPROVE is a randomized, non-comparative multicenter, phase 2 study which evaluated continuous, until progressive disease (PD), or…”
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