Search Results - "Loll, Bernhard"

Towards complete cofactor arrangement in the 3.0 Å resolution structure of photosystem II by Saenger, Wolfram, Zouni, Athina, Loll, Bernhard, Kern, Jan, Biesiadka, Jacek

“…Oxygenic photosynthesis in plants, algae and cyanobacteria is initiated at photosystem II, a homodimeric multisubunit protein-cofactor complex embedded in the…”
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Exchange catalysis by tapasin exploits conserved and allele-specific features of MHC-I molecules by Lan, Huan, Abualrous, Esam T., Sticht, Jana, Fernandez, Laura Maria Arroyo, Werk, Tamina, Weise, Christoph, Ballaschk, Martin, Schmieder, Peter, Loll, Bernhard, Freund, Christian

“…The repertoire of peptides presented by major histocompatibility complex class I (MHC-I) molecules on the cell surface is tailored by the ER-resident peptide…”
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The δ subunit and NTPase HelD institute a two-pronged mechanism for RNA polymerase recycling by Pei, Hao-Hong, Hilal, Tarek, Chen, Zhuo A., Huang, Yong-Heng, Gao, Yuan, Said, Nelly, Loll, Bernhard, Rappsilber, Juri, Belogurov, Georgiy A., Artsimovitch, Irina, Wahl, Markus C.

“…Cellular RNA polymerases (RNAPs) can become trapped on DNA or RNA, threatening genome stability and limiting free enzyme pools, but how RNAP recycling into…”
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Structural Basis for the Action of an All-Purpose Transcription Anti-termination Factor by Krupp, Ferdinand, Said, Nelly, Huang, Yong-Heng, Loll, Bernhard, Bürger, Jörg, Mielke, Thorsten, Spahn, Christian M.T., Wahl, Markus C.

“…Bacteriophage λN protein, a model anti-termination factor, binds nascent RNA and host Nus factors, rendering RNA polymerase resistant to all pause and…”
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The Impression of a Nonexisting Catalytic Effect: The Role of CotB2 in Guiding the Complex Biosynthesis of Cyclooctat-9-en-7-ol by Raz, Keren, Driller, Ronja, Dimos, Nicole, Ringel, Marion, Brück, Thomas, Loll, Bernhard, Major, Dan Thomas

“…Terpene synthases generate terpenes employing diversified carbocation chemistry, including highly specific ring formations, proton and hydride transfers, and…”
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Molecular basis of antibiotic self-resistance in a bee larvae pathogen by Dang, Tam, Loll, Bernhard, Müller, Sebastian, Skobalj, Ranko, Ebeling, Julia, Bulatov, Timur, Gensel, Sebastian, Göbel, Josefine, Wahl, Markus C., Genersch, Elke, Mainz, Andi, Süssmuth, Roderich D.

“…Paenibacillus larvae , the causative agent of the devastating honey-bee disease American Foulbrood, produces the cationic polyketide-peptide hybrid…”
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Towards a comprehensive understanding of the structural dynamics of a bacterial diterpene synthase during catalysis by Driller, Ronja, Janke, Sophie, Fuchs, Monika, Warner, Evelyn, Mhashal, Anil R., Major, Dan Thomas, Christmann, Mathias, Brück, Thomas, Loll, Bernhard

“…Terpenes constitute the largest and structurally most diverse natural product family. Most terpenoids exhibit a stereochemically complex macrocyclic core,…”
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Active zone scaffolds differentially accumulate Unc13 isoforms to tune Ca2+ channel–vesicle coupling by Böhme, Mathias A, Beis, Christina, Reddy-Alla, Suneel, Reynolds, Eric, Mampell, Malou M, Grasskamp, Andreas T, Lützkendorf, Janine, Bergeron, Dominique Dufour, Driller, Jan H, Babikir, Husam, Göttfert, Fabian, Robinson, Iain M, O'Kane, Cahir J, Hell, Stefan W, Wahl, Markus C, Stelzl, Ulrich, Loll, Bernhard, Walter, Alexander M, Sigrist, Stephan J

“…Coupling distances between synaptic vesicles and Ca 2+ channels determine the efficacy of neurotransmission. Böhme et al . find that presynaptic scaffold…”
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Where Water Is Oxidized to Dioxygen: Structure of the Photosynthetic Mn₄Ca Cluster by Yano, Junko, Kern, Jan, Sauer, Kenneth, Latimer, Matthew J, Pushkar, Yulia, Biesiadka, Jacek, Loll, Bernhard, Saenger, Wolfram, Messinger, Johannes, Zouni, Athina, Yachandra, Vittal K

“…The oxidation of water to dioxygen is catalyzed within photosystem II (PSII) by a Mn₄Ca cluster, the structure of which remains elusive. Polarized extended…”
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Biotechnological potential and initial characterization of two novel sesquiterpene synthases from Basidiomycota Coniophora puteana for heterologous production of δ-cadinol by Ringel, Marion, Dimos, Nicole, Himpich, Stephanie, Haack, Martina, Huber, Claudia, Eisenreich, Wolfgang, Schenk, Gerhard, Loll, Bernhard, Brück, Thomas

“…Terpene synthases are versatile catalysts in all domains of life, catalyzing the formation of an enormous variety of different terpenoid secondary metabolites…”
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Understanding the role of active site residues in CotB2 catalysis using a cluster model by Raz, Keren, Driller, Ronja, Brück, Thomas, Loll, Bernhard, Major, Dan T

“…Terpene cyclases are responsible for the initial cyclization cascade in the multistep synthesis of a large number of terpenes. CotB2 is a diterpene cyclase…”
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Concerted transformation of a hyper-paused transcription complex and its reinforcing protein by Zuber, Philipp K., Said, Nelly, Hilal, Tarek, Wang, Bing, Loll, Bernhard, González-Higueras, Jorge, Ramírez-Sarmiento, César A., Belogurov, Georgiy A., Artsimovitch, Irina, Wahl, Markus C., Knauer, Stefan H.

“…RfaH, a paralog of the universally conserved NusG, binds to RNA polymerases (RNAP) and ribosomes to activate expression of virulence genes. In free,…”
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Conformational Plasticity of HLA-B27 Molecules Correlates Inversely With Efficiency of Negative T Cell Selection by Loll, Bernhard, Rückert, Christine, Uchanska-Ziegler, Barbara, Ziegler, Andreas

“…The development of autoimmune disorders is incompletely understood. Inefficient thymic T cell selection against self-peptides presented by major…”
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The first structure of a bacterial diterpene cyclase: CotB2 by Janke, Ronja, Görner, Christian, Hirte, Max, Brück, Thomas, Loll, Bernhard

“…Sesquiterpenes and diterpenes are a diverse class of secondary metabolites that are predominantly derived from plants and some prokaryotes. The properties of…”
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Current understanding and biotechnological application of the bacterial diterpene synthase CotB2 by Driller, Ronja, Garbe, Daniel, Mehlmer, Norbert, Fuchs, Monika, Raz, Keren, Major, Dan Thomas, Brück, Thomas, Loll, Bernhard

“…CotB2 catalyzes the first committed step in cyclooctatin biosynthesis of the soil bacterium To date, CotB2 represents the best studied bacterial diterpene…”
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Towards an understanding of oleate hydratases and their application in industrial processes by Prem, Sophia, Helmer, Carl P O, Dimos, Nicole, Himpich, Stephanie, Brück, Thomas, Garbe, Daniel, Loll, Bernhard

“…Fatty acid hydratases are unique to microorganisms. Their native function is the oxidation of unsaturated C-C bonds to enable detoxification of environmental…”
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Extended DNA threading through a dual-engine motor module of the activating signal co-integrator 1 complex by Jia, Junqiao, Hilal, Tarek, Bohnsack, Katherine E., Chernev, Aleksandar, Tsao, Ning, Bethmann, Juliane, Arumugam, Aruna, Parmely, Lane, Holton, Nicole, Loll, Bernhard, Mosammaparast, Nima, Bohnsack, Markus T., Urlaub, Henning, Wahl, Markus C.

“…Activating signal co-integrator 1 complex (ASCC) subunit 3 (ASCC3) supports diverse genome maintenance and gene expression processes, and contains tandem…”
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Molecular insights into antibiotic resistance - how a binding protein traps albicidin by Rostock, Lida, Driller, Ronja, Grätz, Stefan, Kerwat, Dennis, von Eckardstein, Leonard, Petras, Daniel, Kunert, Maria, Alings, Claudia, Schmitt, Franz-Josef, Friedrich, Thomas, Wahl, Markus C., Loll, Bernhard, Mainz, Andi, Süssmuth, Roderich D.

“…The worldwide emergence of antibiotic resistance poses a serious threat to human health. A molecular understanding of resistance strategies employed by…”
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Bacterial Polysaccharide Specificity of the Pattern Recognition Receptor Langerin Is Highly Species-dependent by Hanske, Jonas, Schulze, Jessica, Aretz, Jonas, McBride, Ryan, Loll, Bernhard, Schmidt, Henrik, Knirel, Yuriy, Rabsch, Wolfgang, Wahl, Markus C., Paulson, James C., Rademacher, Christoph

“…The recognition of pathogen surface polysaccharides by glycan-binding proteins is a cornerstone of innate host defense. Many members of the C-type lectin…”
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X-Ray Damage to the Mn4Ca Complex in Single Crystals of Photosystem II: A Case Study for Metalloprotein Crystallography by Yano, Junko, Kern, Jan, Irrgang, Klaus-Dieter, Latimer, Matthew J, Bergmann, Uwe, Glatzel, Pieter, Pushkar, Yulia, Biesiadka, Jacek, Loll, Bernhard, Sauer, Kenneth, Messinger, Johannes, Zouni, Athina, Yachandra, Vittal K

“…X-ray absorption spectroscopy was used to measure the damage caused by exposure to x-rays to the Mn4Ca active site in single crystals of photosystem II as a…”
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