Search Results - "Lokumcu, Tolga"

The pro-apoptotic Bcl-2 family member Harakiri (HRK) induces cell death in glioblastoma multiforme by Kaya-Aksoy, Ezgi, Cingoz, Ahmet, Senbabaoglu, Filiz, Seker, Fidan, Sur-Erdem, Ilknur, Kayabolen, Alisan, Lokumcu, Tolga, Sahin, Gizem Nur, Karahuseyinoglu, Sercin, Bagci-Onder, Tugba

“…Harakiri (HRK) is a BH3-only protein of the Bcl-2 family and regulates apoptosis by interfering with anti-apoptotic Bcl-2 and Bcl-xL proteins. While its…”
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Proteomic, Metabolomic, and Fatty Acid Profiling of Small Extracellular Vesicles from Glioblastoma Stem-Like Cells and Their Role in Tumor Heterogeneity by Lokumcu, Tolga, Iskar, Murat, Schneider, Martin, Helm, Dominic, Klinke, Glynis, Schlicker, Lisa, Bethke, Frederic, Müller, Gabriele, Richter, Karsten, Poschet, Gernot, Phillips, Emma, Goidts, Violaine

“…Glioblastoma is a deadly brain tumor for which there is no cure. The presence of glioblastoma stem-like cells (GSCs) contributes to the heterogeneous nature of…”
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Integration of transcriptomics, proteomics and loss-of-function screening reveals WEE1 as a target for combination with dasatinib against proneural glioblastoma by Alhalabi, Obada T., Göttmann, Mona, Gold, Maxwell P., Schlue, Silja, Hielscher, Thomas, Iskar, Murat, Kessler, Tobias, Hai, Ling, Lokumcu, Tolga, Cousins, Clara C., Herold-Mende, Christel, Heßling, Bernd, Horschitz, Sandra, Jabali, Ammar, Koch, Philipp, Baumgartner, Ulrich, Day, Bryan W., Wick, Wolfgang, Sahm, Felix, Krieg, Sandro M., Fraenkel, Ernest, Phillips, Emma, Goidts, Violaine

“…Glioblastoma is characterized by a pronounced resistance to therapy with dismal prognosis. Transcriptomics classify glioblastoma into proneural (PN),…”
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A novel patient stratification strategy to enhance the therapeutic efficacy of dasatinib in glioblastoma by Alhalabi, Obada T, Fletcher, Michael N C, Hielscher, Thomas, Kessler, Tobias, Lokumcu, Tolga, Baumgartner, Ulrich, Wittmann, Elena, Schlue, Silja, Göttmann, Mona, Rahman, Shaman, Hai, Ling, Hansen-Palmus, Lea, Puccio, Laura, Nakano, Ichiro, Herold-Mende, Christel, Day, Bryan W, Wick, Wolfgang, Sahm, Felix, Phillips, Emma, Goidts, Violaine

“…Abstract Background Glioblastoma is the most common primary malignancy of the central nervous system with a dismal prognosis. Genomic signatures classify…”
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PDTB-16. ASSESSING THE FUNCTION OF CHROMATIN MODIFYING ENZYMES IN MEDULLOBLASTOMA by Lokumcu, Tolga, Senbabaoglu, Filiz, Oppermann, Udo, Bagci-Onder, Tugba

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