Search Results - "Lokhov, Sergey G."

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    3'-minor groove binder-DNA probes increase sequence specificity at PCR extension temperatures by Kutyavin, I V, Afonina, I A, Mills, A, Gorn, V V, Lukhtanov, E A, Belousov, E S, Singer, M J, Walburger, D K, Lokhov, S G, Gall, A A, Dempcy, R, Reed, M W, Meyer, R B, Hedgpeth, J

    Published in Nucleic acids research (15-01-2000)
    “…DNA probes with conjugated minor groove binder (MGB) groups form extremely stable duplexes with single-stranded DNA targets, allowing shorter probes to be used…”
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    Journal Article
  2. 2

    Novel DNA probes with low background and high hybridization-triggered fluorescence by Lukhtanov, Eugeny A, Lokhov, Sergey G, Gorn, Vladimir V, Podyminogin, Mikhail A, Mahoney, Walt

    Published in Nucleic acids research (01-03-2007)
    “…Novel fluorogenic DNA probes are described. The probes (called Pleiades) have a minor groove binder (MGB) and a fluorophore at the 5'-end and a non-fluorescent…”
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    Exceptional and selective stabilization of A-T rich DNA-DNA duplexes by N-methylpyrrole carboxamide peptides conjugated to oligodeoxynucleotides by Sinyakov, AN, Lokhov, S G, Kutyavin, I V, Gamper, H B, Meyer, RB Jr

    Published in Journal of the American Chemical Society (01-05-1995)
    “…We now report that covalent attachment of a class of minor groove binding agents, the N-methylpyrrolecarboxamide (MPC) peptides, to short thymidylate or…”
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    Journal Article