Search Results - "Lokhande, Megha"
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Adaptive immune response during hepatitis C virus infection
Published in World journal of gastroenterology : WJG (07-04-2014)“…Hepatitis C virus(HCV)infection affects about 170 million people worldwide and it is a major cause of liver cirrhosis and hepatocellular carcinoma.HCV is a…”
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Methodologies for the Analysis of HCV-Specific CD4(+) T Cells
Published in Frontiers in immunology (25-02-2015)“…Virus-specific CD4(+) T cells play a major role in viral infections, such as hepatitis C virus (HCV). Viral clearance is associated with vigorous and…”
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Role of T cell death in maintaining immune tolerance during persistent viral hepatitis
Published in World journal of gastroenterology : WJG (28-03-2013)“…Virus-specific T cells play an important role in the resolution of hepatic infection. However, during chronic hepatitis infection these cells lack their…”
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HCV-specific CD8+ cell detection at week 12 of chronic hepatitis C treatment with PEG-interferon-α2b/ribavirin correlates with infection resolution
Published in Cellular immunology (01-11-2013)“…•Correlation between HCV-specific CTL response restoration and SVR in HCV treatment.•Specific CTL detection during HCV treatment depends on viral load…”
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Bim-mediated apoptosis and PD-1/PD-L1 pathway impair reactivity of PD1 +/CD127 − HCV-specific CD8 + cells targeting the virus in chronic hepatitis C virus infection
Published in Cellular immunology (2011)“…PD-1 molecule promotes anergy and IL-7 receptor (CD127) induces an anti-apoptotic effect on T cells. Correlation between PD-1/CD127 phenotype and hepatitis C…”
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