Factors Affecting Survival in Severe and Very Severe COPD after Admission in ICUs of Tertiary Care Centers of India (FAST COPD): Study Protocol for a Multicentric Cohort Study

Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide. However, there is a lack of comprehensive data from low- and middle-income countries (LMICs) regarding factors influencing COPD outcomes, particularly in regions where biomass exposure is prevalent....

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Published in:	Indian journal of critical care medicine Vol. 28; no. 6; pp. 552 - 560
Main Authors:	Arunachala, Sumalatha, Devapal, Sindhuja, Swamy, Dayana Shre N, Greeshma, Mandya V, Ul Hussain, Imaad, Siddaiah, Jayaraj B, Christopher, Devasahayam J, Malamardi, Sowmya, Ullah, Mohammed Kaleem, Saeed, Mohammed, Parthasarathi, Ashwaghosha, Jeevan, J, Kumar, Jeevan, Harsha, N, Laxmegowda, Basavaraj, Chetak K, Raghavendra, Pongali B, Lokesh, Komarla S, Raj, L Nischal, Suneetha, D K, Basavaraju, M M, Kumar, R Madhu, Basavanagowdappa, H, Suma, M N, Vishwanath, Prashanth M, Babu, Suresh, Ashok, P, Varsha, Tandure, Chandran, Shreya, Venkataraman, Hariharan, Dinesh, H N, Swaroop, Skanda, Ganguly, Koustav, Upadhyay, Swapna, Mahesh, Padukudru A
Format:	Journal Article
Language:	English
Published:	India 01-06-2024
Subjects:	Medicin och hälsovetenskap Obesity Phenotypes Severe and very severe COPD Acute exacerbation Malnutrition Survival Intensive care unit Morbidity
Online Access:	Get full text
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Summary:	Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide. However, there is a lack of comprehensive data from low- and middle-income countries (LMICs) regarding factors influencing COPD outcomes, particularly in regions where biomass exposure is prevalent. The Factors Affecting Survival in Severe and Very Severe COPD Patients Admitted to Tertiary Centers of India (FAST) study aims to address this gap by evaluating factors impacting survival and exacerbation rates among COPD patients in LMICs like India, with a specific focus on biomass exposure, clinical phenotypes, and nutritional status in patients admitted to the Intensive Care Unit (ICU). The FAST study is an observational cohort study conducted in university teaching hospitals across India. The study aims to enroll 1000 COPD patients admitted to the ICU meeting specific inclusion criteria, with follow-up assessments conducted every 6 months over a 2-year period. Data collection includes demographic information, clinical manifestations, laboratory investigations, pulmonary function tests, medications, nutritional status, mental health, and health-related quality of life. Adjudication of exacerbations and mortality will also be undertaken. The FAST study seeks to provide crucial insights into COPD outcomes in LMICs, informing more precise management strategies and mitigating the burden of COPD in these settings. By evaluating factors such as biomass exposure, clinical phenotypes, and nutritional status, the study aims to address key knowledge gaps in COPD research. Arunachala S, Devapal S, Swamy DSN, Greeshma MV, Ul Hussain I, Siddaiah JB, . Factors Affecting Survival in Severe and Very Severe COPD after Admission in ICUs of Tertiary Care Centers of India (FAST COPD): Study Protocol for a Multicentric Cohort Study. Indian J Crit Care Med 2024;28(6):552-560.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0972-5229 1998-359X
DOI:	10.5005/jp-journals-10071-24728