Search Results - "Loke, J"

Placental DNA methylation signatures of maternal smoking during pregnancy and potential impacts on fetal growth by Everson, Todd M., Vives-Usano, Marta, Seyve, Emie, Cardenas, Andres, Lacasaña, Marina, Craig, Jeffrey M., Lesseur, Corina, Baker, Emily R., Fernandez-Jimenez, Nora, Heude, Barbara, Perron, Patrice, Gónzalez-Alzaga, Beatriz, Halliday, Jane, Deyssenroth, Maya A., Karagas, Margaret R., Íñiguez, Carmen, Bouchard, Luigi, Carmona-Sáez, Pedro, Loke, Yuk J., Hao, Ke, Belmonte, Thalia, Charles, Marie A., Martorell-Marugán, Jordi, Muggli, Evelyne, Chen, Jia, Fernández, Mariana F., Tost, Jorg, Gómez-Martín, Antonio, London, Stephanie J., Sunyer, Jordi, Marsit, Carmen J., Lepeule, Johanna, Hivert, Marie-France, Bustamante, Mariona

“…Maternal smoking during pregnancy (MSDP) contributes to poor birth outcomes, in part through disrupted placental functions, which may be reflected in the…”
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Mylotarg has potent anti-leukaemic effect: a systematic review and meta-analysis of anti-CD33 antibody treatment in acute myeloid leukaemia by Loke, J., Khan, J. N., Wilson, J. S., Craddock, C., Wheatley, K.

“…Conventional chemotherapy is ineffective in the majority of patients with acute myeloid leukaemia (AML), and monoclonal antibodies recognising CD33 expressed…”
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FLT3 inhibitors in acute myeloid leukaemia: assessment of clinical effectiveness, adverse events and future research-a systematic review and meta-analysis by Majothi, S, Adams, D, Loke, J, Stevens, S P, Wheatley, K, Wilson, J S

“…FMS-like tyrosine kinase 3 (FLT3) is the most frequent mutation in AML. With two FLT3 inhibitors recently approved by the FDA (midostaurin and gilteritinib),…”
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Blood-derived lysophospholipid sustains hepatic phospholipids and fat storage necessary for hepatoprotection in overnutrition by Chin, Cheen Fei, Galam, Dwight LA, Gao, Liang, Tan, Bryan C, Wong, Bernice H, Chua, Geok-Lin, Y J Loke, Randy, Lim, Yen Ching, Wenk, Markus R, Lim, Miao Shan, Leow, Wei-Qiang, Goh, George Bb, Torta, Federico, Silver, David L

“…The liver has a high demand for phosphatidylcholine (PC) particularly in overnutrition where reduced phospholipid levels have been implicated in the…”
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The myelin water imaging transcriptome: myelin water fraction regionally varies with oligodendrocyte-specific gene expression by Lee, Jaimie J, Scheuren, Paulina S, Liu, Hanwen, Loke, Ryan W J, Laule, Cornelia, Loucks, Catrina M, Kramer, John L K

“…Identifying sensitive and specific measures that can quantify myelin are instrumental in characterizing microstructural changes in neurological conditions…”
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Biallelic mutations in FLNB cause a skeletal dysplasia with 46,XY gonadal dysgenesis by activating β‐catenin by Upadhyay, K., Loke, J., O, V., Taragin, B., Ostrer, H.

“…Filamin B (FLNB) functions as a switch that can affect chrondrocyte development and endochondral bone formation through a series of signaling molecules and…”
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Epigenome-wide analysis in newborn blood spots from monozygotic twins discordant for cerebral palsy reveals consistent regional differences in DNA methylation by Mohandas, Namitha, Bass-Stringer, Sebastian, Maksimovic, Jovana, Crompton, Kylie, Loke, Yuk J, Walstab, Janet, Reid, Susan M, Amor, David J, Reddihough, Dinah, Craig, Jeffrey M

“…Cerebral palsy (CP) is a clinical description for a group of motor disorders that are heterogeneous with respect to causes, symptoms and severity. A diagnosis…”
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Impact of patient: donor HLA disparity on reduced-intensity-conditioned allogeneic stem cell transplants from HLA mismatched unrelated donors for AML: from the ALWP of the EBMT by Loke, J., Labopin, M., Craddock, C., Niederwieser, D., Cornelissen, J., Afansayev, B., Jindra, P., Maertens, J., Blaise, D., Boriskina, K., Gramatzki, M., Ganser, A., Savani, B., Mohty, M., Nagler, A.

“…Patients with acute myeloid leukaemia (AML) who lack a matched sibling or unrelated donor commonly undergo transplantation from a donor matched at 9/10 HLA-A,…”
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Leadership behaviours: effects on job satisfaction, productivity and organizational commitment by CHIOK FOONG LOKE, J.

“…Background  Research in the west has shown that job satisfaction, productivity and organizational commitment are affected by leadership behaviours. The purpose…”
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Rapidly screening variants of uncertain significance in the MAP3K1 gene for phenotypic effects by Loke, J, Ostrer, H

“…Loke J, Ostrer H. Rapidly screening variants of uncertain significance in the MAP3K1 gene for phenotypic effects. DNA sequencing of candidate genes or whole…”
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Acquired isodisomy on chromosome 13 at diagnosis results in impaired overall survival in patients with FLT3-ITD mutant acute myeloid leukaemia by Loke, J C T, Akiki, S, Borrow, J, Ewing, J, Bokhari, S W, Chandra, D, Arrazi, J, Hazlewood, P, Arthur, K, Walsh, J, Membwange, Y, Wandroo, F A, Watts, A, Borg, A, Brock, K, Ferguson, P, Craddock, C, Griffiths, M, Raghavan, M

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DURABLE LONG‐TERM REMISSION IN HIGH‐RISK RELAPSE REFRACTORY LYMPHOMA—20 YEARS’ EXPERIENCE OF ALLOGENEIC HAEMOPOIETIC STEM CELL TRANSPLANT IN SINGAPORE by Loke, J., Low, C. L., Lim, F., Quek, J., Than, H., Goh, Y. T., Linn, Y. C., Diong, C. P., Ho, A., Hwang, W., Hwang, C. C., Koh, L. P., Tan, L. K., Lee, J., Catapia, J., Poon, M., Ng, L.

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Impact of patient support programmes among patients with severe asthma treated with biological therapies: a systematic literature review and indirect treatment comparison by Rabe, Adrian P J, Loke, Wei J, Kielar, Danuta, Morris, Tamsin, Shih, Vivian H, Olinger, Lynda, Musat, Mihaela G, Lan, Zhiyi, Harricharan, Sharada, Fulton, Olivia, Majeed, Azeem, Heaney, Liam G

“…IntroductionEffective treatment of severe asthma requires patient adherence to inhaled and biological medications. Previous work has shown that patient support…”
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Spectroscopic detection of exogenous materials in latent fingerprints treated with powders and lifted off with adhesive tapes by Banas, A., Banas, K., Breese, M. B. H., Loke, J., Lim, S. K.

“…Fingerprint evidence offers great value to criminal investigations since it is an internationally recognized and established means of human identification…”
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Chemical Stabilization of 1T′ Phase Transition Metal Dichalcogenides with Giant Optical Kerr Nonlinearity by Tan, Sherman J. R, Abdelwahab, Ibrahim, Ding, Zijing, Zhao, Xiaoxu, Yang, Tieshan, Loke, Gabriel Z. J, Lin, Han, Verzhbitskiy, Ivan, Poh, Sock Mui, Xu, Hai, Nai, Chang Tai, Zhou, Wu, Eda, Goki, Jia, Baohua, Loh, Kian Ping

“…The 2H-to-1T′ phase transition in transition metal dichalcogenides (TMDs) has been exploited to phase-engineer TMDs for applications in which the metallicity…”
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Health-Promoting Behaviors and Psychosocial Well-Being of University Students in Hong Kong by Lee, Regina L. T., Loke, Alice J. T. Yuen

“…The objective of this study was to examine health‐promoting behaviors and psychosocial well‐being of university students in Hong Kong. A cross‐sectional study…”
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Outcomes of EAM conditioned autologous haematopoietic SCT for lymphoma. A matched pairs retrospective single-centre study analysis by Loke, J, Ward, J, Mahendra, P, Chaganti, S, Malladi, R

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Detection of microscopic particles present as contaminants in latent fingerprints by means of synchrotron radiation-based Fourier transform infra-red micro-imaging by Banas, A, Banas, K, Breese, M B H, Loke, J, Heng Teo, B, Lim, S K

“…Synchrotron radiation-based Fourier transform infra-red (SR-FTIR) micro-imaging has been developed as a rapid, direct and non-destructive technique. This…”
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Correlations between genotype and pharmacological, histological, functional, and clinical phenotypes in malignant hyperthermia susceptibility by Monnier, Nicole, Kozak-Ribbens, Geneviève, Krivosic-Horber, Renée, Nivoche, Yves, Qi, Dong, Kraev, Natasha, Loke, Julian, Sharma, Parveen, Tegazzin, Vincenzo, Figarella-Branger, Dominique, Roméro, Norma, Mezin, Paulette, Bendahan, David, Payen, Jean-François, Depret, Thierry, Maclennan, David H., Lunardi, Joël

“…Malignant hyperthermia susceptibility (MHS) is a subclinical pharmacogenetic disorder caused by an impairment of skeletal muscle calcium homeostasis in…”
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Low-dose Intrathecal Local Anesthetic Does Not Increase the Threshold Current for the Epidural Stimulation Test: A Prospective Observational Trial of Neuraxial Analgesia in Laboring Women by Carvalho, J.C.A, Khemka, R, Loke, J, Tsui, B.C.H

“…(Can J Anesth. 2015;62:265–270)Correct placement of epidural catheters can be confirmed by using the epidural stimulation test (EST), a procedure that has been…”
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