Search Results - "Loizides, Charalambos"

Targeted capture enrichment assay for non-invasive prenatal testing of large and small size sub-chromosomal deletions and duplications by Neofytou, Maria C, Tsangaras, Kyriakos, Kypri, Elena, Loizides, Charalambos, Ioannides, Marios, Achilleos, Achilleas, Mina, Petros, Keravnou, Anna, Sismani, Carolina, Koumbaris, George, Patsalis, Philippos C

“…Noninvasive prenatal testing (NIPT) using whole genome and targeted sequencing has become increasingly accepted for clinical detection of Trisomy 21 and sex…”
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MeDIP combined with in-solution targeted enrichment followed by NGS: Inter-individual methylation variability of fetal-specific biomarkers and their implementation in a proof of concept study for NIPT by Keravnou, Anna, Ioannides, Marios, Loizides, Charalambos, Tsangaras, Kyriakos, Achilleos, Achilleas, Mina, Petros, Kypri, Elena, Hadjidaniel, Michael D, Neofytou, Maria, Kyriacou, Skevi, Sismani, Carolina, Koumbaris, George, Patsalis, Philippos C

“…DNA methylation is the most characterized epigenetic process exhibiting stochastic variation across different tissues and individuals. In non-invasive prenatal…”
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Investigation of Clinically Significant Molecular Aberrations in Patients with Prostate Cancer: Implications for Personalized Treatment, Prognosis and Genetic Testing by Fountzilas, Elena, Kouspou, Maria, Eliades, Alexia, Papadopoulou, Kyriaki, Bournakis, Evangelos, Goussia, Anna, Tsiatas, Marinos, Achilleos, Achilleas, Tsangaras, Kyriakos, Billioud, Gaetan, Loizides, Charalambos, Lemesios, Christos, Kypri, Elena, Ioannides, Marios, Koumbaris, George, Levva, Sofia, Vakalopoulos, Ioannis, Paliouras, Athanasios, Pervana, Stavroula, Koinis, Filippos, Bumci, Redi, Christopoulou, Athina, Meditskou, Soultana, Psyrri, Amanda, Boukovinas, Ioannis, Visvikis, Anastasios, Karavasilis, Vasilios, Koukoulis, George K, Kotsakis, Athanasios, Giannakis, Dimitrios, Fountzilas, George, Patsalis, Philippos C

“…The data on tumor molecular profiling of European patients with prostate cancer is limited. Our aim was to evaluate the prevalence and prognostic and…”
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Model-Based Tumor Growth Dynamics and Therapy Response in a Mouse Model of De Novo Carcinogenesis by Loizides, Charalambos, Iacovides, Demetris, Hadjiandreou, Marios M, Rizki, Gizem, Achilleos, Achilleas, Strati, Katerina, Mitsis, Georgios D

“…Tumorigenesis is a complex, multistep process that depends on numerous alterations within the cell and contribution from the surrounding stroma. The ability to…”
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Targeted capture enrichment followed by NGS: development and validation of a single comprehensive NIPT for chromosomal aneuploidies, microdeletion syndromes and monogenic diseases by Koumbaris, George, Achilleos, Achilleas, Nicolaou, Michalis, Loizides, Charalambos, Tsangaras, Kyriakos, Kypri, Elena, Mina, Petros, Sismani, Carolina, Velissariou, Voula, Christopoulou, Georgia, Constantoulakis, Pantelis, Manolakos, Emmanouil, Papoulidis, Ioannis, Stambouli, Danai, Ioannides, Marios, Patsalis, Philippos

“…Non-invasive prenatal testing (NIPT) has been widely adopted for the detection of fetal aneuploidies and microdeletion syndromes, nevertheless, limited…”
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Genomic Epidemiology of the SARS-CoV-2 Epidemic in Cyprus from November 2020 to October 2021: The Passage of Waves of Alpha and Delta Variants of Concern by Chrysostomou, Andreas C, Vrancken, Bram, Haralambous, Christos, Alexandrou, Maria, Aristokleous, Antonia, Christodoulou, Christina, Gregoriou, Ioanna, Ioannides, Marios, Kalakouta, Olga, Karagiannis, Christos, Koumbaris, George, Loizides, Charalambos, Mendris, Michail, Papastergiou, Panagiotis, Patsalis, Philippos C, Pieridou, Despo, Richter, Jan, Schmitt, Markus, Shammas, Christos, Stylianou, Dora C, Themistokleous, Giorgos, The Comessar Network, Lemey, Philippe, Kostrikis, Leondios G

“…The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in December 2019 resulted in the coronavirus disease 2019 (COVID-19) pandemic,…”
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EORTC-SPECTA Arcagen study, comprehensive genomic profiling and treatment adaptation of rare thoracic cancers by Tagliamento, Marco, Morfouace, Marie, Loizides, Charalambos, Oliveira, Julio, Greillier, Laurent, Raimbourg, Judith, Toffart, Anne-Claire, Chatellier, Thierry, Cloarec, Nicolas, Sullivan, Ivana, Brasiuniene, Birute, Duruisseaux, Michael, Oselin, Kersti, Robert, Marie-Sophie, Fernandes, Carolina, Poncin, Arnaud, Blay, Jean-Yves, Besse, Benjamin, Girard, Nicolas

“…Arcagen (NCT02834884) is a European prospective study aiming at defining the molecular landscape of rare cancers for treatment guidance. We present data from…”
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Whole transcriptome sequence data of 5-FU sensitive and 5-FU resistant tumors generated in a mouse model of de novo carcinogenesis by Iacovides, Demetris, Loizides, Charalambos, Mitsis, Georgios, Strati, Katerina

“…We have performed whole transcriptome sequencing of 5-FU resistant and 5-FU sensitive tumors generated in a mouse model of de novo carcinogenesis that closely…”
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Development of a new methylation‐based fetal fraction estimation assay using multiplex ddPCR by Ioannides, Marios, Achilleos, Achilleas, Kyriakou, Skevi, Kypri, Elena, Loizides, Charalambos, Tsangaras, Kyriakos, Constantinou, Louiza, Koumbaris, George, Patsalis, Philippos C.

“…Background Non‐invasive prenatal testing (NIPT) for fetal aneuploidies has rapidly been incorporated into clinical practice. Current NGS‐based methods can…”
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A mixed effects model framework for the assessment of nonlinear interactions in event-related potentials (ERPs) elicited by identical successive stimuli by Loizides, Charalambos, Achilleos, Achilleas, Iannetti, Gian Domenico, Mitsis, Georgios D.

“…The recording of brain event-related potentials (ERPs) is a widely used technique to investigate the neural basis of sensory perception and cognitive…”
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Assessment of nonlinear interactions in event-related potentials elicited by stimuli presented at short interstimulus intervals using single-trial data by Loizides, Charalambos, Achilleos, Achilleas, Iannetti, Gian Domenico, Mitsis, Georgios D

“…The recording of brain event-related potentials (ERPs) is a widely used technique to investigate the neural basis of sensory perception and cognitive…”
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Multiprocess Dynamic Modeling of Tumor Evolution with Bayesian Tumor-Specific Predictions by Achilleos, Achilleas, Loizides, Charalambos, Hadjiandreou, Marios, Stylianopoulos, Triantafyllos, Mitsis, Georgios D.

“…We propose a sequential probabilistic mixture model for individualized tumor growth forecasting. In contrast to conventional deterministic methods for…”
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Molecular profile and clinical features of patients with gliomas using a broad targeted next generation‑sequencing panel by Romanidou, Ourania, Apostolou, Paraskevi, Kouvelakis, Kyriakos, Tsangaras, Kyriakos, Eliades, Alexia, Achilleos, Achilleas, Loizides, Charalambos, Lemesios, Christos, Ioannides, Marios, Kypri, Elena, Koumbaris, George, Papadopoulou, Kyriaki, Papathanasiou, Athanasios, Rigakos, Georgios, Xanthakis, Ioannis, Afostira, Florenti, Kotoula, Vassiliki, Fountzilas, George, Patsalps, Philippos C

“…Gliomas are the most common malignant primary brain tumors characterized by poor prognosis. The genotyping of tumors using next generation sequencing (NGS)…”
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Clinical Significance of Germline Cancer Predisposing Variants in Unselected Patients with Pancreatic Adenocarcinoma by Fountzilas, Elena, Eliades, Alexia, Koliou, Georgia-Angeliki, Achilleos, Achilleas, Loizides, Charalambos, Tsangaras, Kyriakos, Pectasides, Dimitrios, Sgouros, Joseph, Papakostas, Pavlos, Rallis, Grigorios, Psyrri, Amanda, Papadimitriou, Christos, Oikonomopoulos, Georgios, Ferentinos, Konstantinos, Koumarianou, Anna, Zarkavelis, George, Dervenis, Christos, Aravantinos, Gerasimos, Bafaloukos, Dimitrios, Kosmidis, Paris, Papaxoinis, George, Theochari, Maria, Varthalitis, Ioannis, Kentepozidis, Nikolaos, Rigakos, Georgios, Saridaki, Zacharenia, Nikolaidi, Adamantia, Christopoulou, Athina, Fostira, Florentia, Samantas, Epaminontas, Kypri, Elena, Ioannides, Marios, Koumbaris, George, Fountzilas, George, Patsalis, Philippos C

“…Our aim was to determine the prevalence, prognostic and predictive role of germline pathogenic/likely pathogenic variants (P/LPVs) in cancer predisposing genes…”
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Extensions of the case-control design in genome-wide association studies by Loizides, Charalambos

“…The case-control design is one of the most commonly used designs in genome- wide asociation studies. When we increase the sample size of either the controls…”
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Whole-genome fetal and maternal DNA methylation analysis using MeDIP-NGS for the identification of differentially methylated regions by KERAVNOU, ANNA, IOANNIDES, MARIOS, TSANGARAS, KYRIAKOS, LOIZIDES, CHARALAMBOS, HADJIDANIEL, MICHAEL D., PAPAGEORGIOU, ELISAVET A., KYRIAKOU, SKEVI, ANTONIOU, PAVLOS, MINA, PETROS, ACHILLEOS, ACHILLEAS, NEOFYTOU, MARIA, KYPRI, ELENA, SISMANI, CAROLINA, KOUMBARIS, GEORGE, PATSALIS, PHILIPPOS C.

“…DNA methylation is an epigenetic marker that has been shown to vary significantly across different tissues. Taking advantage of the methylation differences…”
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