Search Results - "Lois, Cristina"
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Performance evaluation of the 5‐Ring GE Discovery MI PET/CT system using the national electrical manufacturers association NU 2‐2012 Standard
Published in Medical physics (Lancaster) (01-07-2019)“…The GE Discovery MI PET/CT system has a modular digital detector design allowing three, four, or five detector block rings that extend the axial field‐of‐view…”
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Menopause Status Moderates Sex Differences in Tau Burden: A Framingham PET Study
Published in Annals of neurology (01-07-2022)“…Objective Women have a higher lifetime risk of Alzheimer's disease (AD) than men. Among cognitively normal (CN) older adults, women exhibit elevated tau…”
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PET imaging of tau protein targets: a methodology perspective
Published in Brain imaging and behavior (01-04-2019)“…The two neuropathological hallmarks of Alzheimer’s disease (AD) are amyloid- β plaques and neurofibrillary tangles of tau protein. Fifteen years ago, Positron…”
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Quantitative PET in the 2020s: a roadmap
Published in Physics in medicine & biology (12-03-2021)“…Positron emission tomography (PET) plays an increasingly important role in research and clinical applications, catalysed by remarkable technical advances and a…”
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Pathological correlates of impaired self-awareness of memory function in Alzheimer's disease
Published in Alzheimer's research & therapy (25-06-2021)“…Impaired self-awareness of memory function, a.k.a. anosognosia, is a common symptom in Alzheimer's disease (AD); however, its pathological correlates remain…”
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Impact of Time-of-Flight on PET Tumor Detection
Published in Journal of Nuclear Medicine (01-08-2009)“…Time-of-flight (TOF) PET uses very fast detectors to improve localization of events along coincidence lines-of-response. This information is then utilized to…”
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Association of cortical microstructure with amyloid-β and tau: impact on cognitive decline, neurodegeneration, and clinical progression in older adults
Published in Molecular psychiatry (01-12-2021)“…Noninvasive biomarkers of early neuronal injury may help identify cognitively normal individuals at risk of developing Alzheimer’s disease (AD). A recent…”
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Nonlinear Distributional Mapping (NoDiM) for harmonization across amyloid-PET radiotracers
Published in NeuroImage (Orlando, Fla.) (01-02-2019)“…There is a growing need in clinical research domains for direct comparability between amyloid-beta (Aβ) Positron Emission Tomography (PET) measures obtained…”
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Associations Between Brainstem Volume and Alzheimer's Disease Pathology in Middle-Aged Individuals of the Framingham Heart Study
Published in Journal of Alzheimer's disease (2022)“…The brainstem is among the first regions to accumulate Alzheimer's disease (AD)-related hyperphosphorylated tau pathology during aging. We aimed to examine…”
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Cortical microstructural changes predict tau accumulation and episodic memory decline in older adults harboring amyloid
Published in Communications medicine (01-08-2023)“…Introduction Non-invasive diffusion-weighted imaging (DWI) to assess brain microstructural changes via cortical mean diffusivity (cMD) has been shown to be…”
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Analytical Study of the Effect of the System Geometry on Photon Sensitivity and Depth of Interaction of Positron Emission Mammography
Published in Journal of Oncology (01-01-2012)“…Positron emission mammography (PEM) cameras are novel-dedicated PET systems optimized to image the breast. For these cameras it is essential to achieve an…”
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Biomass to plastics: From HMF to fructose for the synthesis of 2,5-furandicarboxylic acid over Au/TiO2
Published in Catalysis today (01-02-2025)“…This study focuses on the catalytic synthesis of 2,5-furandicarboxylic acid (FDCA) from 5-hydroxymethylfurfural (HMF). The influences of temperature, O2…”
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Association of cortical microstructure with amyloid-[beta] and tau: impact on cognitive decline, neurodegeneration, and clinical progression in older adults
Published in Molecular psychiatry (01-12-2021)“…Noninvasive biomarkers of early neuronal injury may help identify cognitively normal individuals at risk of developing Alzheimer's disease (AD). A recent…”
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Impact of motion correction on [ 18 F]-MK6240 tau PET imaging
Published in Physics in medicine & biology (15-05-2023)“… Positron emission tomography (PET) imaging of tau deposition using [ F]-MK6240 often involves long acquisitions in older subjects, many of whom exhibit…”
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Pathological correlates of impaired self‐awareness of memory function in dementia: Developing topics
Published in Alzheimer's & dementia (01-12-2020)“…Abstract Background Impaired self‐awareness of memory function (a.k.a. anosognosia) is a common symptom observed in Alzheimer’s disease (AD), however it’s…”
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Pathological correlates of impaired self‐awareness of memory function in dementia
Published in Alzheimer's & dementia (01-12-2020)“…Background Impaired self‐awareness of memory function (a.k.a. anosognosia) is a common symptom observed in Alzheimer’s disease (AD), however it’s pathological…”
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An Assessment of the Impact of Incorporating Time-of-Flight Information into Clinical PET/CT Imaging
Published in Journal of Nuclear Medicine (01-02-2010)“…The introduction of fast scintillators with good stopping power for 511-keV photons has renewed interest in time-of-flight (TOF) PET. The ability to measure…”
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Measurement of Cerebral Perfusion Indices from the Early Phase of [ 18 F]MK6240 Dynamic Tau PET Imaging
Published in Journal of Nuclear Medicine (01-06-2023)“…6-(fluoro- F)-3-(1H-pyrrolo[2,3-c]pyridin-1-yl)isoquinolin-5-amine ([ F]MK6240) has high affinity and selectivity for hyperphosphorylated tau and readily…”
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Kinetic evaluation and assessment of longitudinal changes in reference region and extracerebral [18F]MK-6240 PET uptake
Published in Journal of cerebral blood flow and metabolism (01-04-2023)“…[18F]MK-6240 meningeal/extracerebral off-target binding may impact tau quantification. We examined the kinetics and longitudinal changes of extracerebral and…”
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Silicon sensor probing and radiation studies for the LHCb silicon tracker
Published in Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment (30-11-2006)“…The LHCb Silicon Tracker (ST) will be built using silicon micro-strip technology. A total of 1400 sensors, with strip pitches of approximately 200 μ m and…”
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