Search Results - "Loi, Melissa"
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CDK8 and CDK19 regulate intestinal differentiation and homeostasis via the chromatin remodeling complex SWI/SNF
Published in The Journal of clinical investigation (17-10-2022)“…Initiation and maintenance of transcriptional states are critical for controlling normal tissue homeostasis and differentiation. The cyclin dependent kinases…”
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BIOL-01. GENERATION AND MULTI-OMICS CHARACTERIZATION OF 203 PEDIATRIC CNS TUMOUR MODELS REVEALS NEW THERAPEUTIC VULNERABILITIES
Published in Neuro-oncology (Charlottesville, Va.) (12-06-2023)“…Abstract Pediatric Central Nervous System (CNS) tumors are the leading cause of cancer-related death among children. Identifying new targeted therapies…”
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MODL-17. The Childhood Brain Cancer Cell Line Atlas: A Resource for Biomarker Identification and Therapeutic Development
Published in Neuro-oncology (Charlottesville, Va.) (03-06-2022)“…Abstract Cell lines represent the most versatile and widely used models of cancer and, as such, are critical for identifying and advancing new therapies…”
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SYST-15 GENERATION AND MULTI-DIMENSIONAL PROFILING OF A CHILDHOOD CANCER CELL LINE ATLAS DEFINES NEW THERAPEUTIC OPPORTUNITIES
Published in Neuro-oncology advances (04-08-2023)“…Abstract Paediatric solid tumours are the leading cause of cancer related death amongst children. Identification of paediatric-specific targeted therapies…”
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