Search Results - "Loi, Marisa"

ESCRT-III-driven piecemeal micro-ER-phagy remodels the ER during recovery from ER stress by Loi, Marisa, Raimondi, Andrea, Morone, Diego, Molinari, Maurizio

“…The endoplasmic reticulum (ER) produces about 40% of the nucleated cell’s proteome. ER size and content in molecular chaperones increase upon physiologic and…”
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Translocon component Sec62 acts in endoplasmic reticulum turnover during stress recovery by Fumagalli, Fiorenza, Noack, Julia, Bergmann, Timothy J., Cebollero, Eduardo, Pisoni, Giorgia Brambilla, Fasana, Elisa, Fregno, Ilaria, Galli, Carmela, Loi, Marisa, Soldà, Tatiana, D’Antuono, Rocco, Raimondi, Andrea, Jung, Martin, Melnyk, Armin, Schorr, Stefan, Schreiber, Anne, Simonelli, Luca, Varani, Luca, Wilson-Zbinden, Caroline, Zerbe, Oliver, Hofmann, Kay, Peter, Matthias, Quadroni, Manfredo, Zimmermann, Richard, Molinari, Maurizio

“…The endoplasmic reticulum (ER) is a site of protein biogenesis in eukaryotic cells. Perturbing ER homeostasis activates stress programs collectively called the…”
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Identification of signal peptide features for substrate specificity in human Sec62/Sec63‐dependent ER protein import by Schorr, Stefan, Nguyen, Duy, Haßdenteufel, Sarah, Nagaraj, Nagarjuna, Cavalié, Adolfo, Greiner, Markus, Weissgerber, Petra, Loi, Marisa, Paton, Adrienne W., Paton, James C., Molinari, Maurizio, Förster, Friedrich, Dudek, Johanna, Lang, Sven, Helms, Volkhard, Zimmermann, Richard

“…In mammalian cells, one‐third of all polypeptides are integrated into the membrane or translocated into the lumen of the endoplasmic reticulum (ER) via the…”
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Role of SEC62 in ER maintenance: A link with ER stress tolerance in SEC62-overexpressing tumors? by Bergmann, Timothy J., Fumagalli, Fiorenza, Loi, Marisa, Molinari, Maurizio

“…Amplification of the candidate oncogene TLOC1/SEC62 in tumors correlates with reduced patient survival. The recently reported role of SEC62 as an autophagy…”
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Mechanistic insights in recov-ER-phagy: micro-ER-phagy to recover from stress by Loi, Marisa, Molinari, Maurizio

“…Physiological and pathological stresses may cause swelling of the endoplasmic reticulum (ER), a biosynthetic organelle in eukaryotic cells. Upon conclusion of…”
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Erratum: Corrigendum: Translocon component Sec62 acts in endoplasmic reticulum turnover during stress recovery by Fumagalli, Fiorenza, Noack, Julia, Bergmann, Timothy J., Cebollero, Eduardo, Pisoni, Giorgia Brambilla, Fasana, Elisa, Fregno, Ilaria, Galli, Carmela, Loi, Marisa, Soldà, Tatiana, D'Antuono, Rocco, Raimondi, Andrea, Jung, Martin, Melnyk, Armin, Schorr, Stefan, Schreiber, Anne, Simonelli, Luca, Varani, Luca, Wilson-Zbinden, Caroline, Zerbe, Oliver, Hofmann, Kay, Peter, Matthias, Quadroni, Manfredo, Zimmermann, Richard, Molinari, Maurizio

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ER‐to‐lysosome‐associated degradation of proteasome‐resistant ATZ polymers occurs via receptor‐mediated vesicular transport by Fregno, Ilaria, Fasana, Elisa, Bergmann, Timothy J, Raimondi, Andrea, Loi, Marisa, Soldà, Tatiana, Galli, Carmela, D'Antuono, Rocco, Morone, Diego, Danieli, Alberto, Paganetti, Paolo, van Anken, Eelco, Molinari, Maurizio

“…Maintenance of cellular proteostasis relies on efficient clearance of defective gene products. For misfolded secretory proteins, this involves dislocation from…”
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Abstract LB027: Tracking and decoding the antigen specificity of peripherally derived T cells that infiltrate into solid tumors in patients treated with an autologous T cell therapy, PRIME IL-15 (RPTR-147) by Pajerowski, John David, Gordon, William, Bardwell, Phil, McInnis, Christine, Hwang, Ji Young, Huseni, Tabasum, Agnihotri, Parul, Francis, Josh, Tarr, Christina, Renoux, Florian, Heer, Sebastian, Cerreghetti-Terraneo, Nastassja, Loi, Marisa, Hamilton, Erika, Nikiforow, Sarah, Blumenschein, George, Christea, Mihaela, Osman, Keren, Shields, Anthony, Kluger, Harriet, Obermair, Franz-Josef, Pregibon, Daniel, Kisielow, Jan, Coyle, Anthony, Skoberne, Mojca

“…Abstract PRIME IL-15 (RPTR-147) is a novel non-genetically modified, autologous, multi-clonal T cell product loaded with an IL-15Fc nanogel. The product is…”
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High-resolution profiling of MHC II peptide presentation capacity reveals SARS-CoV-2 CD4 T cell targets and mechanisms of immune escape by Obermair, Franz-Josef, Renoux, Florian, Heer, Sebastian, Lee, Chloe H, Cereghetti, Nastassja, Loi, Marisa, Maestri, Giulia, Haldner, Yannick, Wuigk, Robin, Iosefson, Ohad, Patel, Pooja, Triebel, Katherine, Kopf, Manfred, Swain, Joanna, Kisielow, Jan

“…Understanding peptide presentation by specific MHC alleles is fundamental for controlling physiological functions of T cells and harnessing them for…”
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Correction: Corrigendum: Translocon component Sec62 acts in endoplasmic reticulum turnover during stress recovery by Fumagalli, Fiorenza, Noack, Julia, Bergmann, Timothy J., Cebollero, Eduardo, Pisoni, Giorgia Brambilla, Fasana, Elisa, Fregno, Ilaria, Galli, Carmela, Loi, Marisa, Soldà, Tatiana, D'Antuono, Rocco, Raimondi, Andrea, Jung, Martin, Melnyk, Armin, Schorr, Stefan, Schreiber, Anne, Simonelli, Luca, Varani, Luca, Wilson-Zbinden, Caroline, Zerbe, Oliver, Hofmann, Kay, Peter, Matthias, Quadroni, Manfredo, Zimmermann, Richard, Molinari, Maurizio

“…Nature Cell Biology 18, 1173–1184 (2016); published online 17 October 2016; corrected after print 18 November 2016. In the version of this Article originally…”
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Corrigendum: Translocon component Sec62 acts in endoplasmic reticulum turnover during stress recovery by Fumagalli, Fiorenza, Noack, Julia, Bergmann, Timothy J, Cebollero, Eduardo, Pisoni, Giorgia Brambilla, Fasana, Elisa, Fregno, Ilaria, Galli, Carmela, Loi, Marisa, Soldà, Tatiana, D'Antuono, Rocco, Raimondi, Andrea, Jung, Martin, Melnyk, Armin, Schorr, Stefan, Schreiber, Anne, Simonelli, Luca, Varani, Luca, Wilson-Zbinden, Caroline, Zerbe, Oliver, Hofmann, Kay, Peter, Matthias, Quadroni, Manfredo, Zimmermann, Richard, Molinari, Maurizio

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