Search Results - "Loi, A G"

Antiviral l-Nucleosides Specific for Hepatitis B Virus Infection by BRYANT, Martin L, BRIDGES, Edward G, JUODAWLKIS, Amy, TENNANT, Bud, KORBA, Brent, COTE, Paul, MARION, Pat, CRETTON-SCOTT, Erika, SCHINAZI, Raymond F, SOMMADOSSI, Jean-Pierre, PLACIDI, Laurent, FARAJ, Abdesslem, LOI, Anna-Giulia, PIERRA, Claire, DUKHAN, David, GOSSELIN, Gilles, IMBACH, Jean-Louis, HERNANDEZ, Brenda

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Dihydro(alkylthio)(naphthylmethyl)oxopyrimidines:  Novel Non-Nucleoside Reverse Transcriptase Inhibitors of the S-DABO Series by Mai, Antonello, Artico, Marino, Sbardella, Gianluca, Quartarone, Silvana, Massa, Silvio, Loi, Anna G, De Montis, Antonella, Scintu, Franca, Putzolu, Monica, La Colla, Paolo

“…Novel compounds related to 2-(cyclohexylthio)-3,4-dihydro-5-methyl-6-(3-methylbenzyl)-4-oxopyrimidine (3c, MC 639) have been synthesized and tested as…”
Get full text

2-Sulfonyl-4-chloroanilino Moiety:  A Potent Pharmacophore for the Anti-Human Immunodeficiency Virus Type 1 Activity of Pyrrolyl Aryl Sulfones by Artico, Marino, Silvestri, Romano, Massa, Silvio, Loi, Anna G, Corrias, Simona, Piras, Giovanna, La Colla, Paolo

“…The synthesis and the evaluation of cytotoxicity and anti-HIV-1 activity of new aryl pyrrolyl (8) and aryl indolyl (9) sulfones are reported. Preparation of…”
Get full text

Synthesis and anti-HIV-1 activity of thio analogues of dihydroalkoxybenzyloxopyrimidines by MAI, A, ARTICO, M, SBARDELLA, G, MASSA, S, LOI, A. G, TRAMONTANO, E, SCANO, P, LA COLLA, P

“…Various thio analogues of dihydroalkoxybenzyloxopyrimidines (DABOs), a new class of non-nucleoside reverse transcriptase inhibitors, were found to selectively…”
Get full text

Decomposition Pathways and in Vitro HIV Inhibitory Effects of IsoddA Pronucleotides:  Toward a Rational Approach for Intracellular Delivery of Nucleoside 5‘-Monophosphates by Valette, Gilles, Pompon, Alain, Girardet, Jean-Luc, Cappellacci, Loredana, Franchetti, Palmarisa, Grifantini, Mario, La Colla, Paolo, Loi, Anna Giulia, Périgaud, Christian, Gosselin, Gilles, Imbach, Jean-Louis

“…The decomposition pathways and kinetics in various biological media and the in vitro anti-HIV-1 and anti-HIV-2 activities of four derivatives of the…”
Get full text

5-Alkyl-2-(alkylthio)-6-(2,6-dihalophenylmethyl)-3,4-dihydropyrimidin-4(3H)-ones:  Novel Potent and Selective Dihydro-alkoxy-benzyl-oxopyrimidine Derivatives by Mai, Antonello, Artico, Marino, Sbardella, Gianluca, Massa, Silvio, Novellino, Ettore, Greco, Giovanni, Loi, Anna Giulia, Tramontano, Enzo, Marongiu, Maria Elena, La Colla, Paolo

“…Molecular modeling analysis of compounds belonging to the recently published series of dihydro-alkoxy-benzyl-oxopyrimidines (DABOs), such as S-DABOs and…”
Get full text

Synthesis, Structure, and Antiproliferative Activity of Selenophenfurin, an Inosine 5‘-Monophosphate Dehydrogenase Inhibitor Analogue of Selenazofurin by Franchetti, Palmarisa, Cappellacci, Loredana, Sheikha, Ghassan Abu, Jayaram, Hiremagalur N, Gurudutt, Vivek V, Sint, Thaw, Schneider, Bryan P, Jones, William D, Goldstein, Barry M, Perra, Graziella, De Montis, Antonella, Loi, Anna Giulia, La Colla, Paolo, Grifantini, Mario

“…The synthesis and biological activity of selenophenfurin (5-β-d-ribofuranosylselenophene-3-carboxamide, 1), the selenophene analogue of selenazofurin, are…”
Get full text

1,2,5-Benzothiadiazepine and Pyrrolo[2,1-d]-[1,2,5]Benzothiadiazepine Derivatives with Specific Anti-Human Immunodeficiency Virus Type 1 Activity by Di Santo, R, Costi, R, Artico, M, Massa, S, Marongiu, ME, Loi, AG, De Montis, A, La Colla, P

“…We synthesized and tested as novel inhibitors of human immunodeficiency virus type 1 (HIV-1) bi- and tricyclic thiadiazine ring homologues of…”
Get full text

Phthalein Derivatives as a New Tool for Selectivity in Thymidylate Synthase Inhibition by Costi, Paola M, Rinaldi, Marcella, Tondi, Donatella, Pecorari, Piergiorgio, Barlocco, Daniela, Ghelli, Stefano, Stroud, Robert M, Santi, Daniel V, Stout, Thomas J, Musiu, Chiara, Marangiu, Elena M, Pani, Alessandra, Congiu, Donatella, Loi, Giulia A, La Colla, Paolo

“…A new set of phthalein derivatives stemming from the lead compound, phenolphthalein, were designed to specifically complement structural features of a…”
Get full text

4′- C -Methyl-β-D-ribofuranosyl Purine and Pyrimidine Nucleosides Revisited by Griffon, J.-F., Dukhan, D., Pierra, C., Benzaria, S., Loi, A. G., La Colla, P., Sommadossi, J.-P., Gosselin, G.

“…In order to evaluate their antiviral properties, a series of 4′-C-methyl- β -D-ribofuranosyl purine and pyrimidine nucleosides has been prepared…”
Get full text

Synthesis and antiviral evaluation of some β- l-2′,3′-dideoxy-5-chloropyrimidine nucleosides and pronucleotides by Pierra, Claire, Imbach, Jean-Louis, De Clercq, Erik, Balzarini, Jan, Van Aerschot, Arthur, Herdewijn, Piet, Faraj, Abdesslem, Loi, Anna G., Sommadossi, Jean-Pierre, Gosselin, Gilles

“…The synthesis and in vitro anti human immunodeficiency virus (HIV) and anti-hepatitis B virus (HBV) activities of some unnatural β- l-nucleoside enantiomers…”
Get full text

ANTI-HBV SPECIFIC β-L-2′-DEOXYNUCLEOSIDES by Bryant, Martin L., Bridges, Edward G., Placidi, Laurent, Faraj, Abdesslem, Loi, Anna-Giulia, Pierra, Claire, Dukhan, David, Gosselin, Gilles, Imbach, Jean-Louis, Hernandez, Brenda, Juodawlkis, Amy, Tennant, Bud, Korba, Brent, Cote, Paul, Cretton-Scott, Erika, Schinazi, Raymond F., Sommadossi, Jean-Pierre

“…A unique series of simple unnatural L-nucleosides that specifically inhibit hepatitis B virus (HBV) replication has been discovered. These molecules have in…”
Get full text

Synthesis and Antiviral Activity of 8-Aza Analogs of Chiral [2-(Phosphonomethoxy)propyl]guanines by Franchetti, Palmarisa, Abu Sheikha, Ghassan, Cappellacci, Loredana, Grifantini, Mario, De Montis, Antonella, Piras, Giovanna, Loi, Anna Giulia, La Colla, Paolo

“…(R)- And (S)-8-aza-9(-)[2-(phosphonomethoxy)propyl]guanine [(R)-and (S)-8-aza-PMPG] were synthesized and tested in vitro for anti-human immunodeficiency virus…”
Get full text

Native oligodeoxynucleotides specifically active against human immunodeficiency virus type 1 in vitro: a G-quartet-driven effect? by TONDELLI, L, COLONNA, F. P, GARBESI, A, ZANELLA, S, MARONGIU, M. E, CORRIAS, S, LOI, A. G, LA COLLA, P

“…Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon…”
Get full text

20 IN VITRO ACTIVITY AND PHARMACOLOGIC PROPERTIES OF TWO NOVEL SERIES OF HCV PROTEASE INHIBITORS by Standring, D.N, Parsy, C, Alexandre, F.-R, Derock, M, Leroy, F, Convard, T, La Colla, M, Lallos, L, Loi, A.-G, Musiu, C, Marceddu, T, Poddesu, B, Vargiu, L, Liuzzi, M, Surleraux, D

Get full text

Potent and selective inhibitors of human immunodeficiency virus protease structurally related to L-694,746 by FRANCHETTI, P, PERLINI, P, ABU SHEIKHA, G, CAPPELLACCI, L, GRIFANTINI, M, LOI, A. G, DE MONTIS, A, PANI, A, MARONGIU, M. E, LA COLLA, P

“…A series of human immunodeficiency virus (HIV) protease inhibitors, which are analogues of N-[2(R)-hydroxy-1(S)-…”
Get full text

Novel Indolyl Aryl Sulfones Active against HIV-1 Carrying NNRTI Resistance Mutations:  Synthesis and SAR Studies by Silvestri, Romano, De Martino, Gabriella, La Regina, Giuseppe, Artico, Marino, Massa, Silvio, Vargiu, Laura, Mura, Massimo, Loi, Anna Giulia, Marceddu, Tiziana, La Colla, Paolo

“…The potent anti-HIV-1 activities of L-737,126 (2) and PAS sulfones prompted us to design and test against HIV-1 in acutely infected MT-4 cells a number of…”
Get full text

Antiviral activity and intracellular metabolism of Bis(tButyISATE) phosphotriester of beta -L-2',3' dideoxyadenosine, a potent inhibitor of HIV and HBV replication by Placidi, L, Faraj, A, Loi, A G, Pierra, C, Egron, D, Cretton-Scott, E, Gosselin, G, Perigaud, C, Martin, L T, Schinazi, R F, Imbach, J L, el Kouni, MH, Bryant, M L, Sommadossi, J P

“…The beta -L-nucleoside analogue beta -L-2',3'-dideoxy adenosine ( beta -L-ddA) has been shown to exhibit limited antiviral activities. This was attributed to…”
Get full text

Synthesis, Biological Evaluation, and Binding Mode of Novel 1-[2-(Diarylmethoxy)ethyl]-2-methyl-5-nitroimidazoles Targeted at the HIV-1 Reverse Transcriptase by Silvestri, Romano, Artico, Marino, De Martino, Gabriella, Ragno, Rino, Massa, Silvio, Loddo, Roberta, Murgioni, Chiara, Loi, Anna Giulia, La Colla, Paolo, Pani, Alessandra

“…A novel series of 1-[2-(diarylmethoxy)ethyl]-2-methyl-5-nitroimidazole (DAMNI) analogues were synthesized and tested in cell-based assays and in enzyme assays…”
Get full text

Characterization of the anti-HIV-1 activity of 3,4-dihydro-2-alkoxy-6-benzyl-4-oxopyrimidines (DABOs), new non-nucleoside reverse transcriptase inhibitors by Tramontano, E, Marongiu, M E, de Montis, A, Loi, A G, Artico, M, Massa, S, Mai, A, la Colla, P

“…Novel 3,4-dihydro-6-benzyl-4-oxopyrimidines (DABOs), variously substituted at both the C-2 and C-5 positions of the pyrimidine ring, proved to be specific…”
Get more information