Search Results - "Lohr, Christiane V"

Rapamycin inhibits the secretory phenotype of senescent cells by a Nrf2‐independent mechanism by Wang, Rong, Yu, Zhen, Sunchu, Bharath, Shoaf, James, Dang, Ivana, Zhao, Stephanie, Caples, Kelsey, Bradley, Lynda, Beaver, Laura M., Ho, Emily, Löhr, Christiane V., Perez, Viviana I.

“…Summary Senescent cells contribute to age‐related pathology and loss of function, and their selective removal improves physiological function and extends…”
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Polycyclic aromatic hydrocarbons as skin carcinogens: Comparison of benzo[a]pyrene, dibenzo[def,p]chrysene and three environmental mixtures in the FVB/N mouse by Siddens, Lisbeth K., Larkin, Andrew, Krueger, Sharon K., Bradfield, Christopher A., Waters, Katrina M., Tilton, Susan C., Pereira, Cliff B., Löhr, Christiane V., Arlt, Volker M., Phillips, David H., Williams, David E., Baird, William M.

“…The polycyclic aromatic hydrocarbon (PAH), benzo[a]pyrene (BaP), was compared to dibenzo[def,p]chrysene (DBC) and combinations of three environmental PAH…”
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Ablation of epidermal RXRα in cooperation with activated CDK4 and oncogenic NRAS generates spontaneous and acute neonatal UVB induced malignant metastatic melanomas by Chagani, Sharmeen, Wang, Rong, Carpenter, Evan L, Löhr, Christiane V, Ganguli-Indra, Gitali, Indra, Arup K

“…Understanding the underlying molecular mechanisms involved in the formation of cutaneous malignant melanoma is critical for improved diagnosis and treatment…”
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Reciprocal regulation of BMF and BIRC5 (Survivin) linked to Eomes overexpression in colorectal cancer by Wang, Rong, Kang, Yuki, Löhr, Christiane V, Fischer, Kay A, Bradford, C. Samuel, Johnson, Gavin, Dashwood, Wan Mohaiza, Williams, David E, Ho, Emily, Dashwood, Roderick H

“…Highlights • Eomes, a T-box transcription factor, was found to be overexpressed in human primary colon cancers and colon tumors from a rat preclinical model. •…”
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Activation of the Aryl Hydrocarbon Receptor by 10-Cl-BBQ Prevents Insulitis and Effector T Cell Development Independently of Foxp3+ Regulatory T Cells in Nonobese Diabetic Mice by Ehrlich, Allison K, Pennington, Jamie M, Wang, Xisheng, Rohlman, Diana, Punj, Sumit, Löhr, Christiane V, Newman, Matthew T, Kolluri, Siva K, Kerkvliet, Nancy I

“…Aryl hydrocarbon receptor (AhR) activation by high-affinity ligands mediates immunosuppression in association with increased regulatory T cells (Tregs), making…”
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Epigenetic inactivation of endothelin‐2 and endothelin‐3 in colon cancer by Wang, Rong, Löhr, Christiane V., Fischer, Kay, Dashwood, W. Mohaiza, Greenwood, Jeffrey A., Ho, Emily, Williams, David E., Ashktorab, Hassan, Dashwood, Michael R., Dashwood, Roderick H.

“…Endothelin‐1 (ET‐1) and its receptors are overexpressed in human cancers, but much less is known about the roles of ET‐2 and ET‐3 in cancer etiology. We sought…”
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Cytochrome P450 1b1 in polycyclic aromatic hydrocarbon (PAH)-induced skin carcinogenesis: Tumorigenicity of individual PAHs and coal-tar extract, DNA adduction and expression of select genes in the Cyp1b1 knockout mouse by Siddens, Lisbeth K., Bunde, Kristi L., Harper, Tod A., McQuistan, Tammie J., Löhr, Christiane V., Bramer, Lisa M., Waters, Katrina M., Tilton, Susan C., Krueger, Sharon K., Williams, David E., Baird, William M.

“…FVB/N mice wild-type, heterozygous or null for Cyp 1b1 were used in a two-stage skin tumor study comparing PAH, benzo[a]pyrene (BaP), dibenzo[def,p]chrysene…”
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Divergent roles of p120‐catenin isoforms linked to altered cell viability, proliferation, and invasiveness in carcinogen‐induced rat skin tumors by Wang, Rong, Chen, Ying‐Shiuan, Dashwood, Wan‐Mohaiza, Li, Qingjie, Löhr, Christiane V., Fischer, Kay, Ho, Emily, Williams, David E., Dashwood, Roderick H.

“…The heterocyclic amine 2‐amino‐1‐methyl‐6‐phenylimidazo[4,5‐b]pyridine (PhIP) targets multiple organs for tumorigenesis in the rat, including the colon and the…”
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Nrf2 status affects tumor growth, HDAC3 gene promoter associations, and the response to sulforaphane in the colon by Rajendran, Praveen, Dashwood, Wan-Mohaiza, Li, Li, Kang, Yuki, Kim, Eunah, Johnson, Gavin, Fischer, Kay A, Löhr, Christiane V, Williams, David E, Ho, Emily, Yamamoto, Masayuki, Lieberman, David A, Dashwood, Roderick H

“…The dietary agent sulforaphane (SFN) has been reported to induce nuclear factor erythroid 2 (NF-E2)-related factor 2 (Nrf2)-dependent pathways as well as…”
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Antiproliferative effects of masitinib and imatinib against canine oral fibrosarcoma in vitro by Milovancev, Milan, Helfand, Stuart C, Marley, Kevin, Goodall, Cheri P, Löhr, Christiane V, Bracha, Shay

“…Canine oral fibrosarcoma (COF) is one of the most common oral tumors in dogs and carries a guarded prognosis due to a lack of effective systemic therapeutic…”
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Dibenzo[def,p]chrysene transplacental carcinogenesis in wild‐type, Cyp1b1 knockout, and CYP1B1 humanized mice by Madeen, Erin P., Löhr, Christiane V., You, Hannah, Siddens, Lisbeth K., Krueger, Sharon K., Dashwood, Roderick H., Gonzalez, Frank J., Baird, William M., Ho, Emily, Bramer, Lisa, Waters, Katrina M., Williams, David E.

“…The cytochrome P450 (CYP) 1 family is active toward numerous environmental pollutants, including polycyclic aromatic hydrocarbons (PAHs). Utilizing a mouse…”
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Transcriptome analysis reveals a dynamic and differential transcriptional response to sulforaphane in normal and prostate cancer cells and suggests a role for Sp1 in chemoprevention by Beaver, Laura M., Buchanan, Alex, Sokolowski, Elizabeth I., Riscoe, Allison N., Wong, Carmen P., Chang, Jeff H., Löhr, Christiane V., Williams, David E., Dashwood, Roderick H., Ho, Emily

“…Scope Epidemiological studies provide evidence that consumption of cruciferous vegetables, like broccoli, can reduce the risk of cancer development…”
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Immunohistochemical characterization of intestinal neoplasia in zebrafish Danio rerio indicates epithelial origin by Paquette, Colleen E, Kent, Michael L, Peterson, Tracy S, Wang, Rong, Dashwood, Roderick H, Löhr, Christiane V

“…Spontaneous neoplasia of the intestinal tract in sentinel and moribund zebrafish Danio rerio is common in some zebrafish facilities. We previously classified…”
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A comparison of microscopic ink characteristics of 35 commercially available surgical margin inks by Milovancev, Milan, Löhr, Christiane V., Bildfell, Robert J., Gelberg, Howard B., Heidel, Jerry R., Valentine, Beth A.

“…Objective To compare microscopic characteristics of commercially available surgical margin inks used for surgical pathology specimens. Study Design Prospective…”
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Protective versus promotional effects of white tea and caffeine on PhIP-induced tumorigenesis and β-catenin expression in the rat by Wang, Rong, Dashwood, W.Mohaiza, Löhr, Christiane V., Fischer, Kay A., Pereira, Clifford B., Louderback, Mandy, Nakagama, Hitoshi, Bailey, George S., Williams, David E., Dashwood, Roderick H.

“…A 1 year carcinogenicity bioassay was conducted in rats treated with three short cycles of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)/high-fat (HF)…”
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Esophageal dysfunction in four alpaca crias and a llama cria with vascular ring anomalies by McKenzie, Erica C, Seguin, Bernard, Cebra, Christopher K, Margiocco, Marco L, Anderson, David E, Lohr, Christiane V

“…3 alpaca crias and cadavers of an alpaca cria and a llama cria were evaluated for evidence of esophageal dysfunction. All 5 crias were between 3 and 5 months…”
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Pulmonary arteriovenous malformation in two adult alpacas (Vicugna pacos) by Piripi, Susan, Hustace, Jaime, Carney, Katelyn R, Heidel, Jerry R, Lohr, Christiane V

“…Two cases of pulmonary vascular anomaly in unrelated adult alpacas (Vicugna pacos) are described. In the first case, a 9-year-old intact male alpaca presented…”
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Docosahexaenoic acid (22:6 n-3)-rich microalgae along with methionine supplementation in broiler chickens: effects on production performance, breast muscle quality attributes, lipid profile, and incidence of white striping and myopathy by Khan, Ibrahim A., Parker, Nathan B., Löhr, Christiane V., Cherian, Gita

“…The effect of docosahexaenoic acid (DHA, 22:6 n-3)-rich microalgae and methionine (Met) supplementation on production performance, incidence of breast muscle…”
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Activator protein-2α functions as a master regulator of multiple transcription factors in the mouse liver by Li, Qingjie, Luo, Cunhui, Löhr, Christiane V., Dashwood, Roderick H.

“…Aim:  Activator protein 2α (AP‐2α) belongs to the AP‐2 family of transcription factors that are involved in the regulation of cell proliferation,…”
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Evaluating the impact of organic chromium with flax seed in broiler diets: effects on production performance, breast muscle pathology, and meat quality aspects by Fraz, Ahmad, Parker, Nathan B., Löhr, Christiane V., Cherian, Gita

“…The study investigated the impact of organic chromium (Cr) and flax seed supplementation on live performance, carcass yield, muscle lipid profile,…”
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